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Peptide and Protein Engineering
From Concepts to Biotechnological Applications
Buch von Ana Cecília Roque (u. a.)
Sprache: Englisch

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Beschreibung
This thorough book aims to present the methods that have enabled the success of peptides and proteins in a wide variety of applications. It opens with a section on chemical tools applied to the production or engineering of peptides and proteins, and concludes with a collection of chapters on biological approaches used to engineer structure and function in peptides and proteins. As a book in the Springer Protocols Handbooks series, chapters include the kind of detailed descriptions and tips necessary for successful results in practice.
Authoritative and practical, Peptide and Protein Engineering: From Concepts to Biotechnological Applications will be of great use to scientists in academia and industry seeking a better understanding of the emerging principles and methodologies in peptide and protein engineering.
This thorough book aims to present the methods that have enabled the success of peptides and proteins in a wide variety of applications. It opens with a section on chemical tools applied to the production or engineering of peptides and proteins, and concludes with a collection of chapters on biological approaches used to engineer structure and function in peptides and proteins. As a book in the Springer Protocols Handbooks series, chapters include the kind of detailed descriptions and tips necessary for successful results in practice.
Authoritative and practical, Peptide and Protein Engineering: From Concepts to Biotechnological Applications will be of great use to scientists in academia and industry seeking a better understanding of the emerging principles and methodologies in peptide and protein engineering.
Zusammenfassung

Includes cutting-edge techniques

Provides important details essential for successful results

Contains key implementation advice from the experts

Inhaltsverzeichnis

SEA Ligation is Accelerated at Midly Acidic pH: Application to the Formation of Difficult Peptide Junctions.- The Problem of Aspartimide Formation during Protein Chemical Synthesis Using SEA-Mediated Ligation.- Using the Interactive Tool of the Protein Chemical Synthesis Database.- Only a "Click" Away: Development of Arginine-Rich Peptide-Based Materials Using Click Chemistry.- Fluoroglycoproteins by Copper-Free Strain-Promoted Azide-Alkyne Cycloaddition.- Hybrid Silylated Peptides for the Design of Bio-Functionalized Materials.- Synthesis of Peptide-Oligoethylene Glycol (OEG) Conjugates for Multivalent Modification of Nanomaterials.- Phage Display Methodologies.- Whole-Bacterium Ribosome Display Selection for Isolation of Anti-Bacterial Affitins.- CIS Display: DNA-Based Technology as a Platform for Discovery of Therapeutic Biologics.- Building Scarless Gene Libraries in the Chromosome of Bacteria.- Streptavidin (Sav)-Based Artificial Metalloenzymes: Cofactor Design Considerations and Large Scale Expression of Host Protein Variants.- Integrated Bacterial Production of Large Combinatorial Libraries of Cyclic Oligopeptides and Functional Screening for the Identification of Chemical Rescuers of Pathogenic Protein Misfolding and Aggregation.- Site-Specific Incorporation of Non-Canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli.

Details
Erscheinungsjahr: 2020
Fachbereich: Biophysik
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Buch
Reihe: Springer Protocols Handbooks
Inhalt: xi
289 S.
17 s/w Illustr.
54 farbige Illustr.
289 p. 71 illus.
54 illus. in color.
ISBN-13: 9781071607190
ISBN-10: 1071607197
Sprache: Englisch
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Roque, Ana Cecília
Iranzo, Olga
Herausgeber: Olga Iranzo/Ana Cecília Roque
Auflage: 1st ed. 2020
Hersteller: Springer US
Springer US, New York, N.Y.
Springer Protocols Handbooks
Maße: 260 x 183 x 22 mm
Von/Mit: Ana Cecília Roque (u. a.)
Erscheinungsdatum: 09.07.2020
Gewicht: 0,772 kg
Artikel-ID: 118070866
Zusammenfassung

Includes cutting-edge techniques

Provides important details essential for successful results

Contains key implementation advice from the experts

Inhaltsverzeichnis

SEA Ligation is Accelerated at Midly Acidic pH: Application to the Formation of Difficult Peptide Junctions.- The Problem of Aspartimide Formation during Protein Chemical Synthesis Using SEA-Mediated Ligation.- Using the Interactive Tool of the Protein Chemical Synthesis Database.- Only a "Click" Away: Development of Arginine-Rich Peptide-Based Materials Using Click Chemistry.- Fluoroglycoproteins by Copper-Free Strain-Promoted Azide-Alkyne Cycloaddition.- Hybrid Silylated Peptides for the Design of Bio-Functionalized Materials.- Synthesis of Peptide-Oligoethylene Glycol (OEG) Conjugates for Multivalent Modification of Nanomaterials.- Phage Display Methodologies.- Whole-Bacterium Ribosome Display Selection for Isolation of Anti-Bacterial Affitins.- CIS Display: DNA-Based Technology as a Platform for Discovery of Therapeutic Biologics.- Building Scarless Gene Libraries in the Chromosome of Bacteria.- Streptavidin (Sav)-Based Artificial Metalloenzymes: Cofactor Design Considerations and Large Scale Expression of Host Protein Variants.- Integrated Bacterial Production of Large Combinatorial Libraries of Cyclic Oligopeptides and Functional Screening for the Identification of Chemical Rescuers of Pathogenic Protein Misfolding and Aggregation.- Site-Specific Incorporation of Non-Canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli.

Details
Erscheinungsjahr: 2020
Fachbereich: Biophysik
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Buch
Reihe: Springer Protocols Handbooks
Inhalt: xi
289 S.
17 s/w Illustr.
54 farbige Illustr.
289 p. 71 illus.
54 illus. in color.
ISBN-13: 9781071607190
ISBN-10: 1071607197
Sprache: Englisch
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Roque, Ana Cecília
Iranzo, Olga
Herausgeber: Olga Iranzo/Ana Cecília Roque
Auflage: 1st ed. 2020
Hersteller: Springer US
Springer US, New York, N.Y.
Springer Protocols Handbooks
Maße: 260 x 183 x 22 mm
Von/Mit: Ana Cecília Roque (u. a.)
Erscheinungsdatum: 09.07.2020
Gewicht: 0,772 kg
Artikel-ID: 118070866
Warnhinweis