Peptide and Protein Engineering | Buch

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Cover: 9781071607190 | Peptide and Protein Engineering | Ana Cecília Roque (u. a.) | Buch

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Sprache: Englisch

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Beschreibung

This thorough book aims to present the methods that have enabled the success of peptides and proteins in a wide variety of applications. It opens with a section on chemical tools applied to the production or engineering of peptides and proteins, and concludes with a collection of chapters on biological approaches used to engineer structure and function in peptides and proteins. As a book in the Springer Protocols Handbooks series, chapters include the kind of detailed descriptions and tips necessary for successful results in practice.

Authoritative and practical, Peptide and Protein Engineering: From Concepts to Biotechnological Applications will be of great use to scientists in academia and industry seeking a better understanding of the emerging principles and methodologies in peptide and protein engineering.

Zusammenfassung

Includes cutting-edge techniques

Provides important details essential for successful results

Contains key implementation advice from the experts

Inhaltsverzeichnis

SEA Ligation is Accelerated at Midly Acidic pH: Application to the Formation of Difficult Peptide Junctions.- The Problem of Aspartimide Formation during Protein Chemical Synthesis Using SEA-Mediated Ligation.- Using the Interactive Tool of the Protein Chemical Synthesis Database.- Only a "Click" Away: Development of Arginine-Rich Peptide-Based Materials Using Click Chemistry.- Fluoroglycoproteins by Copper-Free Strain-Promoted Azide-Alkyne Cycloaddition.- Hybrid Silylated Peptides for the Design of Bio-Functionalized Materials.- Synthesis of Peptide-Oligoethylene Glycol (OEG) Conjugates for Multivalent Modification of Nanomaterials.- Phage Display Methodologies.- Whole-Bacterium Ribosome Display Selection for Isolation of Anti-Bacterial Affitins.- CIS Display: DNA-Based Technology as a Platform for Discovery of Therapeutic Biologics.- Building Scarless Gene Libraries in the Chromosome of Bacteria.- Streptavidin (Sav)-Based Artificial Metalloenzymes: Cofactor Design Considerations and Large Scale Expression of Host Protein Variants.- Integrated Bacterial Production of Large Combinatorial Libraries of Cyclic Oligopeptides and Functional Screening for the Identification of Chemical Rescuers of Pathogenic Protein Misfolding and Aggregation.- Site-Specific Incorporation of Non-Canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli.

Details

Erscheinungsjahr:	2020
Fachbereich:	Biophysik
Genre:	Biologie
Rubrik:	Naturwissenschaften & Technik
Medium:	Buch
Seiten:	304
Reihe:	Springer Protocols Handbooks
Inhalt:	xi 289 S. 17 s/w Illustr. 54 farbige Illustr. 289 p. 71 illus. 54 illus. in color.
ISBN-13:	9781071607190
ISBN-10:	1071607197
Sprache:	Englisch
Ausstattung / Beilage:	HC runder Rücken kaschiert
Einband:	Gebunden
Redaktion:	Roque, Ana Cecília Iranzo, Olga
Herausgeber:	Olga Iranzo/Ana Cecília Roque
Auflage:	1st ed. 2020
Hersteller:	Springer US Springer US, New York, N.Y. Springer Protocols Handbooks
Maße:	260 x 183 x 22 mm
Von/Mit:	Ana Cecília Roque (u. a.)
Erscheinungsdatum:	09.07.2020
Gewicht:	0,772 kg