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Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them.
The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.
Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them.
The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.
GENERAL ASPECTS OF ANALOGUE-BASED DRUG DISCOVERY
Analogues as a Means of Discovering New Drugs
Drug Likeness and Analogue-Based Drug Discovery
Privileged Structures and Analog-Based Drug Discovery
SELECTED EXAMPLES FROM THE ANALOGUE-BASED DRUG DISCOVERIES
Development of Anti-Ulcer H2-Receptor Histamine Antagonists
Esomeprazole in the Framework of Proton-Pump Inhibitor Development
The Development of a New Proton-Pump Inhibitor: The Case History of Pantoprazole
Optimizing the Clinical Pharmacologic Properties of the HMG-CoA Reductase Inhibitors
Optimizing Antihypertensive Therapy by Angiotensin Receptor Blockers
Optimizing Antihypertensive Therapy by Angiotensin-Converting Enzyme Inhibitors
Case Study of Lacidipine in the Research of New Calcium Antagonists
Selective Beta-Adrenergic Receptor-Blocking Agents
Case Study: "Esmolol Stat" [1]
Development of Organic Nitrates for Coronary Heart Disease
Development of Opioid Receptor Ligands
Stigmines
Structural Analogues of Clozapine
Quinolone Antibiotics: The Development of Moxifloxacin
The Development of Bisphosphonates as Drugs
Cisplatin and its Analogs for Cancer Chemotherapy
The History of Drospirenone
Histamine H1 Blockers: From Relative Failures to Blockbusters Within Series of Analogues
Corticosteroids: From Natural Products to Useful Analogues
| Fachbereich: | Toxikologie |
|---|---|
| Genre: | Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Buch |
| ISBN-13: | 9783527312573 |
| ISBN-10: | 3527312579 |
| Sprache: | Englisch |
| Herstellernummer: | 1131257 000 |
| Redaktion: |
IUPAC
Fischer, János Ganellin, C. Robin |
| Auflage: | 1. Auflage |
| Hersteller: | Wiley-VCH |
| Abbildungen: | 262 SW-Abb., 39 Tabellen |
| Maße: | 246 x 186 x 35 mm |
| Von/Mit: | IUPAC (u. a.) |
| Gewicht: | 1,172 kg |
GENERAL ASPECTS OF ANALOGUE-BASED DRUG DISCOVERY
Analogues as a Means of Discovering New Drugs
Drug Likeness and Analogue-Based Drug Discovery
Privileged Structures and Analog-Based Drug Discovery
SELECTED EXAMPLES FROM THE ANALOGUE-BASED DRUG DISCOVERIES
Development of Anti-Ulcer H2-Receptor Histamine Antagonists
Esomeprazole in the Framework of Proton-Pump Inhibitor Development
The Development of a New Proton-Pump Inhibitor: The Case History of Pantoprazole
Optimizing the Clinical Pharmacologic Properties of the HMG-CoA Reductase Inhibitors
Optimizing Antihypertensive Therapy by Angiotensin Receptor Blockers
Optimizing Antihypertensive Therapy by Angiotensin-Converting Enzyme Inhibitors
Case Study of Lacidipine in the Research of New Calcium Antagonists
Selective Beta-Adrenergic Receptor-Blocking Agents
Case Study: "Esmolol Stat" [1]
Development of Organic Nitrates for Coronary Heart Disease
Development of Opioid Receptor Ligands
Stigmines
Structural Analogues of Clozapine
Quinolone Antibiotics: The Development of Moxifloxacin
The Development of Bisphosphonates as Drugs
Cisplatin and its Analogs for Cancer Chemotherapy
The History of Drospirenone
Histamine H1 Blockers: From Relative Failures to Blockbusters Within Series of Analogues
Corticosteroids: From Natural Products to Useful Analogues
| Fachbereich: | Toxikologie |
|---|---|
| Genre: | Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Buch |
| ISBN-13: | 9783527312573 |
| ISBN-10: | 3527312579 |
| Sprache: | Englisch |
| Herstellernummer: | 1131257 000 |
| Redaktion: |
IUPAC
Fischer, János Ganellin, C. Robin |
| Auflage: | 1. Auflage |
| Hersteller: | Wiley-VCH |
| Abbildungen: | 262 SW-Abb., 39 Tabellen |
| Maße: | 246 x 186 x 35 mm |
| Von/Mit: | IUPAC (u. a.) |
| Gewicht: | 1,172 kg |
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