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TRANSCATHETER MITRAL VALVE THERAPIES
An essential survey of the advancing field of transcatheter mitral valve repair and replacement
Minimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat's most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapy--though they are getting closer and closer to this goal.
Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement's widespread adoption, the book's international group of contributors discuss the improvements to be made in repair and replacement procedures, as well as the adjunctive use of imaging and pharmacologic therapies. This ground-breaking text:
* Provides detailed explanations of transcatheter repair, transcatheter replacement, and adjunctive procedures
* Features chapters on the use of imaging to aid in patient selection, procedure planning, and intra-operative guidance
* Discusses the importance of minimally invasive approaches for mitral valve repair
* Examines anticoagulation following transcatheter mitral valve interventions
* Outlines the possible future of transcatheter mitral valve therapy
Transcatheter Mitral Valve Therapies is an important, up-to-date resource for interventional cardiologists, as well as all clinical researchers and practitioners seeking information on this vital and developing treatment.
An essential survey of the advancing field of transcatheter mitral valve repair and replacement
Minimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat's most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapy--though they are getting closer and closer to this goal.
Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement's widespread adoption, the book's international group of contributors discuss the improvements to be made in repair and replacement procedures, as well as the adjunctive use of imaging and pharmacologic therapies. This ground-breaking text:
* Provides detailed explanations of transcatheter repair, transcatheter replacement, and adjunctive procedures
* Features chapters on the use of imaging to aid in patient selection, procedure planning, and intra-operative guidance
* Discusses the importance of minimally invasive approaches for mitral valve repair
* Examines anticoagulation following transcatheter mitral valve interventions
* Outlines the possible future of transcatheter mitral valve therapy
Transcatheter Mitral Valve Therapies is an important, up-to-date resource for interventional cardiologists, as well as all clinical researchers and practitioners seeking information on this vital and developing treatment.
TRANSCATHETER MITRAL VALVE THERAPIES
An essential survey of the advancing field of transcatheter mitral valve repair and replacement
Minimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat's most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapy--though they are getting closer and closer to this goal.
Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement's widespread adoption, the book's international group of contributors discuss the improvements to be made in repair and replacement procedures, as well as the adjunctive use of imaging and pharmacologic therapies. This ground-breaking text:
* Provides detailed explanations of transcatheter repair, transcatheter replacement, and adjunctive procedures
* Features chapters on the use of imaging to aid in patient selection, procedure planning, and intra-operative guidance
* Discusses the importance of minimally invasive approaches for mitral valve repair
* Examines anticoagulation following transcatheter mitral valve interventions
* Outlines the possible future of transcatheter mitral valve therapy
Transcatheter Mitral Valve Therapies is an important, up-to-date resource for interventional cardiologists, as well as all clinical researchers and practitioners seeking information on this vital and developing treatment.
An essential survey of the advancing field of transcatheter mitral valve repair and replacement
Minimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat's most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapy--though they are getting closer and closer to this goal.
Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement's widespread adoption, the book's international group of contributors discuss the improvements to be made in repair and replacement procedures, as well as the adjunctive use of imaging and pharmacologic therapies. This ground-breaking text:
* Provides detailed explanations of transcatheter repair, transcatheter replacement, and adjunctive procedures
* Features chapters on the use of imaging to aid in patient selection, procedure planning, and intra-operative guidance
* Discusses the importance of minimally invasive approaches for mitral valve repair
* Examines anticoagulation following transcatheter mitral valve interventions
* Outlines the possible future of transcatheter mitral valve therapy
Transcatheter Mitral Valve Therapies is an important, up-to-date resource for interventional cardiologists, as well as all clinical researchers and practitioners seeking information on this vital and developing treatment.
Über den Autor
Edited by
Ron Waksman, MD, Director of Clinical Research and Advanced Education, MedStar Cardiovascular Research Network, Cleveland Clinic, Washington, DC, USA.
Toby Rogers, MD, PhD, Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC; Cardiovascular and Pulmonary Branch, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Inhaltsverzeichnis
List of Contributors xvii
Introduction--The Mitral Book xxiii
1 The Pathology of Mitral Valve Disease 1
Maria E. Romero, Sho Torii, and Renu Virmani
1.1 Introduction 1
1.2 General Anatomy of the Mitral Valve 1
1.2.1 Mitral Annulus 1
1.2.2 Leaflets 3
1.2.3 Chordae Tendineae and Papillary Muscles 5
1.2.4 Papillary Muscles and Left Ventricle 5
1.3 Pathology of Mitral Valve 5
1.3.1 Mitral Valve Stenosis 5
1.3.2 Aging Changes and Mitral Annulus Calcification (MAC) 6
1.3.3 Acute Mitral Regurgitation 8
1.3.4 Chronic Mitral Regurgitation 8
1.3.5 Degenerative MR; Myxomatous Degeneration of the Mitral Valve 8
1.3.6 Functional MR 10
References 11
2 The Importance of Minimally Invasive Approaches for Mitral Valve Repair 15
Bobby Yanagawa and Niv Ad
2.1 Introduction to Minimally Invasive Mitral Valve Surgery 15
2.2 The Importance of MICS MVS 16
2.3 Patient Selection 17
2.4 Surgical Setup--Fibrillating Heart MVS 18
2.5 Alternatives for Cannulation 19
2.6 Alternatives to Myocardial Protection 19
2.7 Mitral Valve Repair 20
2.8 Outcomes 20
2.9 Initiating Minimally Invasive Mitral Valve Repair Program 21
2.10 Conclusion 22
References 22
3 When to Intervene--Should Surgical Guidelines Apply to Transcatheter Techniques in Treating Mitral
Regurgitation? 25
Samir Kapadia, Rishi Puri, Kinjal Banerjee, and Lars G. Svensson
3.1 Introduction 25
3.2 Primary MR 25
3.2.1 Current Guideline Recommendations 25
3.2.2 Transcatheter Therapies--New Guideline Applications? 26
3.3 Secondary MR 29
3.3.1 Current Guideline Recommendations 29
3.4 Conclusions 31
References 32
4 Transcatheter Mitral Valve Therapies: A Three-Dimensional Echocardiographic View 35
Shmuel Schwartzenberg, Chaim Yosefy, and Alexander Sagie
4.1 Introduction 35
4.1.1 Mitral Valve Anatomy 35
4.1.2 Mitral Valve Structure and Function 35
4.1.3 Mitral Regurgitation Severity 36
4.1.4 Diagnosis of MR Severity: Proximal Isovelocity Surface Area Method 36
4.1.5 Diagnosis of MR Severity: Vena Contracta Method 37
4.1.6 Primary and Secondary MR 37
4.1.7 Mitral Regurgitation and Cardiovascular Death and Morbidity 38
4.1.8 Screening for MitraClip Suitability 40
4.1.9 MitraClip Procedure Guidance 41
4.1.10 Transseptal Puncture 41
4.1.11 MitraClip Delivery Guidance 42
4.1.12 Adequacy of MitraClip Implantation Assessment 43
4.1.13 Other Technologies 45
4.2 Conclusions 45
References 45
5 CMR Assessment of Mitral Regurgitation 51
Daniel Knight and Vivek Muthurangu
5.1 Introduction 51
5.2 Pulse Sequences Used in CMR 52
5.2.1 Cine Imaging 52
5.2.2 Phase Contrast Imaging 52
5.3 Assessment of MR Severity 52
5.3.1 Qualitative Assessment 52
5.3.2 Quantitative Assessment 55
5.3.3 Technical Considerations for the Quantitative Assessment of MR by CMR 56
5.4 Identification of MR Etiology 57
5.4.1 Primary MR 57
5.4.2 Secondary MR 57
5.5 The Role of CMR Assessment of MR in Clinical Practice 58
5.6 Conclusions 58
References 58
6 CT Planning for TMVR and Predicting LVOT Obstruction 63
Dee Dee Wang, Mayra Guerrero, Brian O'Neill, Pedro A. Villablanca Spinetto, James Lee, Tiberio Frisoli, Marvin Eng, and William O'Neill
6.1 Introduction 63
6.2 History of Imaging for Mitral Valve Disease 63
6.2.1 TAVR CT Planning 63
6.2.2 Surgical and Transcatheter Mitral Interventions 63
6.3 Concept of Aortic and Mitral Valve Technology Development 64
6.4 Basics of CT Imaging Acquisition 66
6.5 Definition of Mitral Valve and TMVR device Landing Zone 66
6.6 Definition of LVOT 66
6.7 CT Methods for Neo-LVOT prediction modeling 67
6.8 CT Validation of Neo-LVOT Prediction Modeling Post-TMVR 68
6.9 Correlation Between Pre- and Post-TMVR CT Neo-LVOT Prediction Modeling 69
6.10 What Else Has CT Planning for TMVR Taught Us? 70
Acknowledgments 72
References 72
7 General Principles and State-of-the-Art Echocardiographic Evaluation of the Mitral Valve 75
Federico M. Asch and Diego Medvedofsky
7.1 Introduction 75
7.2 Mechanism and Etiology of Chronic MR 75
7.2.1 Transthoracic Echocardiography 76
7.2.1.1 Assessment of MR Severity 76
7.2.2 Qualitative Assessment 76
7.2.2.1 Color Flow Doppler 76
7.3 Continuous Wave (CW) Density Jet 79
7.3.1 Semi-Quantitative Assessment 79
7.3.1.1 VC Width 79
7.4 Pulmonary Vein Flow/Mitral Inflow 79
7.4.1 Quantitative Assessment 80
7.5 Selection of Best Candidates for Interventions of the Mitral Valve 82
7.5.1 Echocardiographic Criteria of COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) Trial 84
References 84
8 Intraprocedural Echocardiography for MitraClip 87
Philip Haines and Sumbal A. Janjua
8.1 Introduction 87
8.2 Pre-Procedure Evaluation 88
8.3 Importance of the Baseline Study - TEE 88
8.4 The Transseptal Puncture 95
8.5 Guiding MitraClip System to Mitral Valve 98
8.6 Intraprocedural Guidance of Clip within Mitral Valve and Leaflets 102
8.7 Post-Clip-Deployment Assessment of Mitral Valve Function 103
8.8 Assessment of Complications and Iatrogenic ASD 105
References 112
9 Intraprocedural Echocardiography for Transcatheter Mitral Valve Replacement 115
Patrick T. Gleason, John C. Lisko, and Stamatios Lerakis
9.1 Introduction 115
9.2 Baseline Mitral Valve Assessment 115
9.3 Access to the Left Atrium, Left Ventricle, and Mitral Valve 116
9.4 Predeployment and Deployment Monitoring 118
9.5 Postdeployment Evaluation 120
References 122
10 Transcatheter Repair: MitraClip for Degenerative Mitral Regurgitation 125
Ted Feldman
10.1 Surgery for Degenerative Mitral Regurgitation 125
10.2 Evidence Base for MitraClip 125
10.3 Challenges for the MitraClip Procedure 130
10.4 Evaluation of MitraClip for Less than Prohibitive-Risk DMR Patients 131
10.5 Future Directions for MitraClip and Alternative Approaches for Leaflet Repair 133
10.6 Summary 135
References 136
11 MitraClip(TM) for Secondary Mitral Regurgitation 139
Brian J. Forrestal and Toby Rogers
11.1 Introduction 139
[...]opean and US Clinical Practice Guidelines 139
11.3 The MitraClip System 140
11.4 MitraClip Preprocedural Planning 140
11.5 Surgical Outcomes Data 140
11.6 The COAPT and MITRA-FR Trials 141
11.7 Summary and Conclusions 144
References 144
12 The Edwards PASCAL Transcatheter Valve Repair System 147
Mirjam Winkel, Stephan Windecker, and Fabien Praz
12.1 Introduction 147
12.2 The Edwards PASCAL(TM) Transcatheter Valve Repair System 147
12.3 Implantation Procedure 148
12.4 Compassionate-Use and Early Feasibility Data 150
12.5 Future Developments 151
References 152
13 The Development of a Novel Percutaneous Treatment for Secondary Mitral Regurgitation--The Carillon(r) Mitral Contour System(r) 153
Steven L. Goldberg
13.1 Introduction 153
13.2 REDUCE-FMR 157
13.3 The CARILLON Trial 160
13.4 Summary 161
References 161
14 A Fully Percutaneous Mitral Ring: The Cardioband System 163
Antonio Mangieri, Enrico Poletti, and Azeem Latib
14.1 Introduction 163
14.2 Mitral Annulus Anatomy 163
14.3 Pathophysiological Role of the Mitral Annulus in Mitral Regurgitation 164
14.3.1 Mitral Annulus in FMR 164
14.3.2 Mitral Annulus in DMR 164
14.4 Surgical Annuloplasty in Mitral Regurgitation 164
14.5 The Cardioband System: Description of the Device 165
14.6 Procedural Planning 165
14.7 Clinical Studies 168
14.8 Possible Complications Related to the Implantation of Cardioband 170
14.9 Recurrence of Mitral Regurgitation Following Cardioband Implantation 171
14.10 Cardioband in Combination with Other Devices 172
14.11 Conclusions 173
References 173
15 Transcatheter Mitral Cerclage Annuloplasty 175
Christopher Bruce, June-Hong Kim, Toby Rogers, and Robert J. Lederman
15.1 Introduction 175
15.2 Cerclage Anatomy and Function 175
15.3 Limitations of Coronary Sinus Annuloplasty 176
15.4 Cerclage Annuloplasty Device 177
15.5 The Cerclage Procedure 177
15.6 Preclinical Experiments 178
15.7 Initial Human Experience 178
15.8 Future Directions 180
15.9 Summary 182
Competing Interests 183
References 183
16 The Transapical Off-Pump Mitral Valve Repair with the NeoChord Implantation (TOP-MINI) 185
Stefan Bertog, Laura Vaskelyte, Nalan Schnelle, Iris Grunwald, Ilona Hofmann, Sameer Gafoor, Markus Reinartz, Predrag Matic, Bojan Jovanovic, Kolja Sievert, Michèle Jaqueline Lembens, and Horst Sievert
16.1 Introduction 185
16.2 Technology 185
16.3 Patient Selection 186
16.4 Procedure 186
16.5 Echocardiographic Guidance 191
16.6 Examples 191
16.6.1 Ideal Anatomy 191
16.6.2 Acceptable Anatomy 191
16.6.3 Challenging Anatomy 192
16.6.4 Data 192
16.7 Conclusion 194
References 195
17 AltaValve(TM)--A Transcatheter Mitral Valve Regurgitation Treatment Technology 197
Katherine Kumar, PhD and Saravana Kumar, PhD
17.1 Clinical Need 197
17.2 Device Description 198
17.2.1 Principle of Operation 198
17.2.2 Device Construction 199
17.2.2.1 Stent 200
17.2.2.2 Stent Cap 200
17.2.2.3 Tissue Valve 200
17.2.2.4 Fabric Skirts and Sutures 200
17.2.3 Delivery Systems 200
17.3 Anatomical Imaging and Sizing 202
17.4 Preclinical and Clinical Experience 203
17.4.1 Animal Studies 203
17.5 Human Clinical Experience 204
17.6 Summary 205
References 206
18 The ARTO Transcatheter Mitral Valve Repair System 209
Andrejs Erglis, Inga Narbute, Agnese Strenge, and Samantha E. Greene
18.1 Device Description 209
18.2 Procedural Details 209
18.3 Clinical Experience with the ARTO System 212
18.4 Unique Features of the ARTO System 216
References 216
19 Transcatheter Mitral Annuloplasty: The Millipede Device 219
Jason H. Rogers and Steven F. Bolling
19.1 Background 219
19.2 The Millipede Device 219
19.3 Millipede Implantation Procedure 220
19.4 Surgical Millipede Implants 220
19.5 Millipede Clinical Results 222
19.6 Clinical Implications 223
19.7 Summary 226
Author Disclosures 226
References 226
20 Transapical and Transseptal Access for Transcatheter Mitral Valve Replacement: Techniques and Devices 227
James Edelman and Vinod...
Introduction--The Mitral Book xxiii
1 The Pathology of Mitral Valve Disease 1
Maria E. Romero, Sho Torii, and Renu Virmani
1.1 Introduction 1
1.2 General Anatomy of the Mitral Valve 1
1.2.1 Mitral Annulus 1
1.2.2 Leaflets 3
1.2.3 Chordae Tendineae and Papillary Muscles 5
1.2.4 Papillary Muscles and Left Ventricle 5
1.3 Pathology of Mitral Valve 5
1.3.1 Mitral Valve Stenosis 5
1.3.2 Aging Changes and Mitral Annulus Calcification (MAC) 6
1.3.3 Acute Mitral Regurgitation 8
1.3.4 Chronic Mitral Regurgitation 8
1.3.5 Degenerative MR; Myxomatous Degeneration of the Mitral Valve 8
1.3.6 Functional MR 10
References 11
2 The Importance of Minimally Invasive Approaches for Mitral Valve Repair 15
Bobby Yanagawa and Niv Ad
2.1 Introduction to Minimally Invasive Mitral Valve Surgery 15
2.2 The Importance of MICS MVS 16
2.3 Patient Selection 17
2.4 Surgical Setup--Fibrillating Heart MVS 18
2.5 Alternatives for Cannulation 19
2.6 Alternatives to Myocardial Protection 19
2.7 Mitral Valve Repair 20
2.8 Outcomes 20
2.9 Initiating Minimally Invasive Mitral Valve Repair Program 21
2.10 Conclusion 22
References 22
3 When to Intervene--Should Surgical Guidelines Apply to Transcatheter Techniques in Treating Mitral
Regurgitation? 25
Samir Kapadia, Rishi Puri, Kinjal Banerjee, and Lars G. Svensson
3.1 Introduction 25
3.2 Primary MR 25
3.2.1 Current Guideline Recommendations 25
3.2.2 Transcatheter Therapies--New Guideline Applications? 26
3.3 Secondary MR 29
3.3.1 Current Guideline Recommendations 29
3.4 Conclusions 31
References 32
4 Transcatheter Mitral Valve Therapies: A Three-Dimensional Echocardiographic View 35
Shmuel Schwartzenberg, Chaim Yosefy, and Alexander Sagie
4.1 Introduction 35
4.1.1 Mitral Valve Anatomy 35
4.1.2 Mitral Valve Structure and Function 35
4.1.3 Mitral Regurgitation Severity 36
4.1.4 Diagnosis of MR Severity: Proximal Isovelocity Surface Area Method 36
4.1.5 Diagnosis of MR Severity: Vena Contracta Method 37
4.1.6 Primary and Secondary MR 37
4.1.7 Mitral Regurgitation and Cardiovascular Death and Morbidity 38
4.1.8 Screening for MitraClip Suitability 40
4.1.9 MitraClip Procedure Guidance 41
4.1.10 Transseptal Puncture 41
4.1.11 MitraClip Delivery Guidance 42
4.1.12 Adequacy of MitraClip Implantation Assessment 43
4.1.13 Other Technologies 45
4.2 Conclusions 45
References 45
5 CMR Assessment of Mitral Regurgitation 51
Daniel Knight and Vivek Muthurangu
5.1 Introduction 51
5.2 Pulse Sequences Used in CMR 52
5.2.1 Cine Imaging 52
5.2.2 Phase Contrast Imaging 52
5.3 Assessment of MR Severity 52
5.3.1 Qualitative Assessment 52
5.3.2 Quantitative Assessment 55
5.3.3 Technical Considerations for the Quantitative Assessment of MR by CMR 56
5.4 Identification of MR Etiology 57
5.4.1 Primary MR 57
5.4.2 Secondary MR 57
5.5 The Role of CMR Assessment of MR in Clinical Practice 58
5.6 Conclusions 58
References 58
6 CT Planning for TMVR and Predicting LVOT Obstruction 63
Dee Dee Wang, Mayra Guerrero, Brian O'Neill, Pedro A. Villablanca Spinetto, James Lee, Tiberio Frisoli, Marvin Eng, and William O'Neill
6.1 Introduction 63
6.2 History of Imaging for Mitral Valve Disease 63
6.2.1 TAVR CT Planning 63
6.2.2 Surgical and Transcatheter Mitral Interventions 63
6.3 Concept of Aortic and Mitral Valve Technology Development 64
6.4 Basics of CT Imaging Acquisition 66
6.5 Definition of Mitral Valve and TMVR device Landing Zone 66
6.6 Definition of LVOT 66
6.7 CT Methods for Neo-LVOT prediction modeling 67
6.8 CT Validation of Neo-LVOT Prediction Modeling Post-TMVR 68
6.9 Correlation Between Pre- and Post-TMVR CT Neo-LVOT Prediction Modeling 69
6.10 What Else Has CT Planning for TMVR Taught Us? 70
Acknowledgments 72
References 72
7 General Principles and State-of-the-Art Echocardiographic Evaluation of the Mitral Valve 75
Federico M. Asch and Diego Medvedofsky
7.1 Introduction 75
7.2 Mechanism and Etiology of Chronic MR 75
7.2.1 Transthoracic Echocardiography 76
7.2.1.1 Assessment of MR Severity 76
7.2.2 Qualitative Assessment 76
7.2.2.1 Color Flow Doppler 76
7.3 Continuous Wave (CW) Density Jet 79
7.3.1 Semi-Quantitative Assessment 79
7.3.1.1 VC Width 79
7.4 Pulmonary Vein Flow/Mitral Inflow 79
7.4.1 Quantitative Assessment 80
7.5 Selection of Best Candidates for Interventions of the Mitral Valve 82
7.5.1 Echocardiographic Criteria of COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) Trial 84
References 84
8 Intraprocedural Echocardiography for MitraClip 87
Philip Haines and Sumbal A. Janjua
8.1 Introduction 87
8.2 Pre-Procedure Evaluation 88
8.3 Importance of the Baseline Study - TEE 88
8.4 The Transseptal Puncture 95
8.5 Guiding MitraClip System to Mitral Valve 98
8.6 Intraprocedural Guidance of Clip within Mitral Valve and Leaflets 102
8.7 Post-Clip-Deployment Assessment of Mitral Valve Function 103
8.8 Assessment of Complications and Iatrogenic ASD 105
References 112
9 Intraprocedural Echocardiography for Transcatheter Mitral Valve Replacement 115
Patrick T. Gleason, John C. Lisko, and Stamatios Lerakis
9.1 Introduction 115
9.2 Baseline Mitral Valve Assessment 115
9.3 Access to the Left Atrium, Left Ventricle, and Mitral Valve 116
9.4 Predeployment and Deployment Monitoring 118
9.5 Postdeployment Evaluation 120
References 122
10 Transcatheter Repair: MitraClip for Degenerative Mitral Regurgitation 125
Ted Feldman
10.1 Surgery for Degenerative Mitral Regurgitation 125
10.2 Evidence Base for MitraClip 125
10.3 Challenges for the MitraClip Procedure 130
10.4 Evaluation of MitraClip for Less than Prohibitive-Risk DMR Patients 131
10.5 Future Directions for MitraClip and Alternative Approaches for Leaflet Repair 133
10.6 Summary 135
References 136
11 MitraClip(TM) for Secondary Mitral Regurgitation 139
Brian J. Forrestal and Toby Rogers
11.1 Introduction 139
[...]opean and US Clinical Practice Guidelines 139
11.3 The MitraClip System 140
11.4 MitraClip Preprocedural Planning 140
11.5 Surgical Outcomes Data 140
11.6 The COAPT and MITRA-FR Trials 141
11.7 Summary and Conclusions 144
References 144
12 The Edwards PASCAL Transcatheter Valve Repair System 147
Mirjam Winkel, Stephan Windecker, and Fabien Praz
12.1 Introduction 147
12.2 The Edwards PASCAL(TM) Transcatheter Valve Repair System 147
12.3 Implantation Procedure 148
12.4 Compassionate-Use and Early Feasibility Data 150
12.5 Future Developments 151
References 152
13 The Development of a Novel Percutaneous Treatment for Secondary Mitral Regurgitation--The Carillon(r) Mitral Contour System(r) 153
Steven L. Goldberg
13.1 Introduction 153
13.2 REDUCE-FMR 157
13.3 The CARILLON Trial 160
13.4 Summary 161
References 161
14 A Fully Percutaneous Mitral Ring: The Cardioband System 163
Antonio Mangieri, Enrico Poletti, and Azeem Latib
14.1 Introduction 163
14.2 Mitral Annulus Anatomy 163
14.3 Pathophysiological Role of the Mitral Annulus in Mitral Regurgitation 164
14.3.1 Mitral Annulus in FMR 164
14.3.2 Mitral Annulus in DMR 164
14.4 Surgical Annuloplasty in Mitral Regurgitation 164
14.5 The Cardioband System: Description of the Device 165
14.6 Procedural Planning 165
14.7 Clinical Studies 168
14.8 Possible Complications Related to the Implantation of Cardioband 170
14.9 Recurrence of Mitral Regurgitation Following Cardioband Implantation 171
14.10 Cardioband in Combination with Other Devices 172
14.11 Conclusions 173
References 173
15 Transcatheter Mitral Cerclage Annuloplasty 175
Christopher Bruce, June-Hong Kim, Toby Rogers, and Robert J. Lederman
15.1 Introduction 175
15.2 Cerclage Anatomy and Function 175
15.3 Limitations of Coronary Sinus Annuloplasty 176
15.4 Cerclage Annuloplasty Device 177
15.5 The Cerclage Procedure 177
15.6 Preclinical Experiments 178
15.7 Initial Human Experience 178
15.8 Future Directions 180
15.9 Summary 182
Competing Interests 183
References 183
16 The Transapical Off-Pump Mitral Valve Repair with the NeoChord Implantation (TOP-MINI) 185
Stefan Bertog, Laura Vaskelyte, Nalan Schnelle, Iris Grunwald, Ilona Hofmann, Sameer Gafoor, Markus Reinartz, Predrag Matic, Bojan Jovanovic, Kolja Sievert, Michèle Jaqueline Lembens, and Horst Sievert
16.1 Introduction 185
16.2 Technology 185
16.3 Patient Selection 186
16.4 Procedure 186
16.5 Echocardiographic Guidance 191
16.6 Examples 191
16.6.1 Ideal Anatomy 191
16.6.2 Acceptable Anatomy 191
16.6.3 Challenging Anatomy 192
16.6.4 Data 192
16.7 Conclusion 194
References 195
17 AltaValve(TM)--A Transcatheter Mitral Valve Regurgitation Treatment Technology 197
Katherine Kumar, PhD and Saravana Kumar, PhD
17.1 Clinical Need 197
17.2 Device Description 198
17.2.1 Principle of Operation 198
17.2.2 Device Construction 199
17.2.2.1 Stent 200
17.2.2.2 Stent Cap 200
17.2.2.3 Tissue Valve 200
17.2.2.4 Fabric Skirts and Sutures 200
17.2.3 Delivery Systems 200
17.3 Anatomical Imaging and Sizing 202
17.4 Preclinical and Clinical Experience 203
17.4.1 Animal Studies 203
17.5 Human Clinical Experience 204
17.6 Summary 205
References 206
18 The ARTO Transcatheter Mitral Valve Repair System 209
Andrejs Erglis, Inga Narbute, Agnese Strenge, and Samantha E. Greene
18.1 Device Description 209
18.2 Procedural Details 209
18.3 Clinical Experience with the ARTO System 212
18.4 Unique Features of the ARTO System 216
References 216
19 Transcatheter Mitral Annuloplasty: The Millipede Device 219
Jason H. Rogers and Steven F. Bolling
19.1 Background 219
19.2 The Millipede Device 219
19.3 Millipede Implantation Procedure 220
19.4 Surgical Millipede Implants 220
19.5 Millipede Clinical Results 222
19.6 Clinical Implications 223
19.7 Summary 226
Author Disclosures 226
References 226
20 Transapical and Transseptal Access for Transcatheter Mitral Valve Replacement: Techniques and Devices 227
James Edelman and Vinod...
Details
| Erscheinungsjahr: | 2021 |
|---|---|
| Fachbereich: | Allgemeine Lexika |
| Genre: | Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Buch |
| Seiten: | 400 |
| Inhalt: | 400 S. |
| ISBN-13: | 9781119490685 |
| ISBN-10: | 1119490685 |
| Sprache: | Englisch |
| Herstellernummer: | 1W119490680 |
| Einband: | Gebunden |
| Redaktion: |
Waksman, Ron
Rogers, Toby |
| Herausgeber: | Ron Waksman/Toby Rogers |
| Hersteller: | Wiley |
| Maße: | 257 x 188 x 28 mm |
| Von/Mit: | Ron Waksman (u. a.) |
| Erscheinungsdatum: | 24.05.2021 |
| Gewicht: | 1,021 kg |
Über den Autor
Edited by
Ron Waksman, MD, Director of Clinical Research and Advanced Education, MedStar Cardiovascular Research Network, Cleveland Clinic, Washington, DC, USA.
Toby Rogers, MD, PhD, Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC; Cardiovascular and Pulmonary Branch, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Inhaltsverzeichnis
List of Contributors xvii
Introduction--The Mitral Book xxiii
1 The Pathology of Mitral Valve Disease 1
Maria E. Romero, Sho Torii, and Renu Virmani
1.1 Introduction 1
1.2 General Anatomy of the Mitral Valve 1
1.2.1 Mitral Annulus 1
1.2.2 Leaflets 3
1.2.3 Chordae Tendineae and Papillary Muscles 5
1.2.4 Papillary Muscles and Left Ventricle 5
1.3 Pathology of Mitral Valve 5
1.3.1 Mitral Valve Stenosis 5
1.3.2 Aging Changes and Mitral Annulus Calcification (MAC) 6
1.3.3 Acute Mitral Regurgitation 8
1.3.4 Chronic Mitral Regurgitation 8
1.3.5 Degenerative MR; Myxomatous Degeneration of the Mitral Valve 8
1.3.6 Functional MR 10
References 11
2 The Importance of Minimally Invasive Approaches for Mitral Valve Repair 15
Bobby Yanagawa and Niv Ad
2.1 Introduction to Minimally Invasive Mitral Valve Surgery 15
2.2 The Importance of MICS MVS 16
2.3 Patient Selection 17
2.4 Surgical Setup--Fibrillating Heart MVS 18
2.5 Alternatives for Cannulation 19
2.6 Alternatives to Myocardial Protection 19
2.7 Mitral Valve Repair 20
2.8 Outcomes 20
2.9 Initiating Minimally Invasive Mitral Valve Repair Program 21
2.10 Conclusion 22
References 22
3 When to Intervene--Should Surgical Guidelines Apply to Transcatheter Techniques in Treating Mitral
Regurgitation? 25
Samir Kapadia, Rishi Puri, Kinjal Banerjee, and Lars G. Svensson
3.1 Introduction 25
3.2 Primary MR 25
3.2.1 Current Guideline Recommendations 25
3.2.2 Transcatheter Therapies--New Guideline Applications? 26
3.3 Secondary MR 29
3.3.1 Current Guideline Recommendations 29
3.4 Conclusions 31
References 32
4 Transcatheter Mitral Valve Therapies: A Three-Dimensional Echocardiographic View 35
Shmuel Schwartzenberg, Chaim Yosefy, and Alexander Sagie
4.1 Introduction 35
4.1.1 Mitral Valve Anatomy 35
4.1.2 Mitral Valve Structure and Function 35
4.1.3 Mitral Regurgitation Severity 36
4.1.4 Diagnosis of MR Severity: Proximal Isovelocity Surface Area Method 36
4.1.5 Diagnosis of MR Severity: Vena Contracta Method 37
4.1.6 Primary and Secondary MR 37
4.1.7 Mitral Regurgitation and Cardiovascular Death and Morbidity 38
4.1.8 Screening for MitraClip Suitability 40
4.1.9 MitraClip Procedure Guidance 41
4.1.10 Transseptal Puncture 41
4.1.11 MitraClip Delivery Guidance 42
4.1.12 Adequacy of MitraClip Implantation Assessment 43
4.1.13 Other Technologies 45
4.2 Conclusions 45
References 45
5 CMR Assessment of Mitral Regurgitation 51
Daniel Knight and Vivek Muthurangu
5.1 Introduction 51
5.2 Pulse Sequences Used in CMR 52
5.2.1 Cine Imaging 52
5.2.2 Phase Contrast Imaging 52
5.3 Assessment of MR Severity 52
5.3.1 Qualitative Assessment 52
5.3.2 Quantitative Assessment 55
5.3.3 Technical Considerations for the Quantitative Assessment of MR by CMR 56
5.4 Identification of MR Etiology 57
5.4.1 Primary MR 57
5.4.2 Secondary MR 57
5.5 The Role of CMR Assessment of MR in Clinical Practice 58
5.6 Conclusions 58
References 58
6 CT Planning for TMVR and Predicting LVOT Obstruction 63
Dee Dee Wang, Mayra Guerrero, Brian O'Neill, Pedro A. Villablanca Spinetto, James Lee, Tiberio Frisoli, Marvin Eng, and William O'Neill
6.1 Introduction 63
6.2 History of Imaging for Mitral Valve Disease 63
6.2.1 TAVR CT Planning 63
6.2.2 Surgical and Transcatheter Mitral Interventions 63
6.3 Concept of Aortic and Mitral Valve Technology Development 64
6.4 Basics of CT Imaging Acquisition 66
6.5 Definition of Mitral Valve and TMVR device Landing Zone 66
6.6 Definition of LVOT 66
6.7 CT Methods for Neo-LVOT prediction modeling 67
6.8 CT Validation of Neo-LVOT Prediction Modeling Post-TMVR 68
6.9 Correlation Between Pre- and Post-TMVR CT Neo-LVOT Prediction Modeling 69
6.10 What Else Has CT Planning for TMVR Taught Us? 70
Acknowledgments 72
References 72
7 General Principles and State-of-the-Art Echocardiographic Evaluation of the Mitral Valve 75
Federico M. Asch and Diego Medvedofsky
7.1 Introduction 75
7.2 Mechanism and Etiology of Chronic MR 75
7.2.1 Transthoracic Echocardiography 76
7.2.1.1 Assessment of MR Severity 76
7.2.2 Qualitative Assessment 76
7.2.2.1 Color Flow Doppler 76
7.3 Continuous Wave (CW) Density Jet 79
7.3.1 Semi-Quantitative Assessment 79
7.3.1.1 VC Width 79
7.4 Pulmonary Vein Flow/Mitral Inflow 79
7.4.1 Quantitative Assessment 80
7.5 Selection of Best Candidates for Interventions of the Mitral Valve 82
7.5.1 Echocardiographic Criteria of COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) Trial 84
References 84
8 Intraprocedural Echocardiography for MitraClip 87
Philip Haines and Sumbal A. Janjua
8.1 Introduction 87
8.2 Pre-Procedure Evaluation 88
8.3 Importance of the Baseline Study - TEE 88
8.4 The Transseptal Puncture 95
8.5 Guiding MitraClip System to Mitral Valve 98
8.6 Intraprocedural Guidance of Clip within Mitral Valve and Leaflets 102
8.7 Post-Clip-Deployment Assessment of Mitral Valve Function 103
8.8 Assessment of Complications and Iatrogenic ASD 105
References 112
9 Intraprocedural Echocardiography for Transcatheter Mitral Valve Replacement 115
Patrick T. Gleason, John C. Lisko, and Stamatios Lerakis
9.1 Introduction 115
9.2 Baseline Mitral Valve Assessment 115
9.3 Access to the Left Atrium, Left Ventricle, and Mitral Valve 116
9.4 Predeployment and Deployment Monitoring 118
9.5 Postdeployment Evaluation 120
References 122
10 Transcatheter Repair: MitraClip for Degenerative Mitral Regurgitation 125
Ted Feldman
10.1 Surgery for Degenerative Mitral Regurgitation 125
10.2 Evidence Base for MitraClip 125
10.3 Challenges for the MitraClip Procedure 130
10.4 Evaluation of MitraClip for Less than Prohibitive-Risk DMR Patients 131
10.5 Future Directions for MitraClip and Alternative Approaches for Leaflet Repair 133
10.6 Summary 135
References 136
11 MitraClip(TM) for Secondary Mitral Regurgitation 139
Brian J. Forrestal and Toby Rogers
11.1 Introduction 139
[...]opean and US Clinical Practice Guidelines 139
11.3 The MitraClip System 140
11.4 MitraClip Preprocedural Planning 140
11.5 Surgical Outcomes Data 140
11.6 The COAPT and MITRA-FR Trials 141
11.7 Summary and Conclusions 144
References 144
12 The Edwards PASCAL Transcatheter Valve Repair System 147
Mirjam Winkel, Stephan Windecker, and Fabien Praz
12.1 Introduction 147
12.2 The Edwards PASCAL(TM) Transcatheter Valve Repair System 147
12.3 Implantation Procedure 148
12.4 Compassionate-Use and Early Feasibility Data 150
12.5 Future Developments 151
References 152
13 The Development of a Novel Percutaneous Treatment for Secondary Mitral Regurgitation--The Carillon(r) Mitral Contour System(r) 153
Steven L. Goldberg
13.1 Introduction 153
13.2 REDUCE-FMR 157
13.3 The CARILLON Trial 160
13.4 Summary 161
References 161
14 A Fully Percutaneous Mitral Ring: The Cardioband System 163
Antonio Mangieri, Enrico Poletti, and Azeem Latib
14.1 Introduction 163
14.2 Mitral Annulus Anatomy 163
14.3 Pathophysiological Role of the Mitral Annulus in Mitral Regurgitation 164
14.3.1 Mitral Annulus in FMR 164
14.3.2 Mitral Annulus in DMR 164
14.4 Surgical Annuloplasty in Mitral Regurgitation 164
14.5 The Cardioband System: Description of the Device 165
14.6 Procedural Planning 165
14.7 Clinical Studies 168
14.8 Possible Complications Related to the Implantation of Cardioband 170
14.9 Recurrence of Mitral Regurgitation Following Cardioband Implantation 171
14.10 Cardioband in Combination with Other Devices 172
14.11 Conclusions 173
References 173
15 Transcatheter Mitral Cerclage Annuloplasty 175
Christopher Bruce, June-Hong Kim, Toby Rogers, and Robert J. Lederman
15.1 Introduction 175
15.2 Cerclage Anatomy and Function 175
15.3 Limitations of Coronary Sinus Annuloplasty 176
15.4 Cerclage Annuloplasty Device 177
15.5 The Cerclage Procedure 177
15.6 Preclinical Experiments 178
15.7 Initial Human Experience 178
15.8 Future Directions 180
15.9 Summary 182
Competing Interests 183
References 183
16 The Transapical Off-Pump Mitral Valve Repair with the NeoChord Implantation (TOP-MINI) 185
Stefan Bertog, Laura Vaskelyte, Nalan Schnelle, Iris Grunwald, Ilona Hofmann, Sameer Gafoor, Markus Reinartz, Predrag Matic, Bojan Jovanovic, Kolja Sievert, Michèle Jaqueline Lembens, and Horst Sievert
16.1 Introduction 185
16.2 Technology 185
16.3 Patient Selection 186
16.4 Procedure 186
16.5 Echocardiographic Guidance 191
16.6 Examples 191
16.6.1 Ideal Anatomy 191
16.6.2 Acceptable Anatomy 191
16.6.3 Challenging Anatomy 192
16.6.4 Data 192
16.7 Conclusion 194
References 195
17 AltaValve(TM)--A Transcatheter Mitral Valve Regurgitation Treatment Technology 197
Katherine Kumar, PhD and Saravana Kumar, PhD
17.1 Clinical Need 197
17.2 Device Description 198
17.2.1 Principle of Operation 198
17.2.2 Device Construction 199
17.2.2.1 Stent 200
17.2.2.2 Stent Cap 200
17.2.2.3 Tissue Valve 200
17.2.2.4 Fabric Skirts and Sutures 200
17.2.3 Delivery Systems 200
17.3 Anatomical Imaging and Sizing 202
17.4 Preclinical and Clinical Experience 203
17.4.1 Animal Studies 203
17.5 Human Clinical Experience 204
17.6 Summary 205
References 206
18 The ARTO Transcatheter Mitral Valve Repair System 209
Andrejs Erglis, Inga Narbute, Agnese Strenge, and Samantha E. Greene
18.1 Device Description 209
18.2 Procedural Details 209
18.3 Clinical Experience with the ARTO System 212
18.4 Unique Features of the ARTO System 216
References 216
19 Transcatheter Mitral Annuloplasty: The Millipede Device 219
Jason H. Rogers and Steven F. Bolling
19.1 Background 219
19.2 The Millipede Device 219
19.3 Millipede Implantation Procedure 220
19.4 Surgical Millipede Implants 220
19.5 Millipede Clinical Results 222
19.6 Clinical Implications 223
19.7 Summary 226
Author Disclosures 226
References 226
20 Transapical and Transseptal Access for Transcatheter Mitral Valve Replacement: Techniques and Devices 227
James Edelman and Vinod...
Introduction--The Mitral Book xxiii
1 The Pathology of Mitral Valve Disease 1
Maria E. Romero, Sho Torii, and Renu Virmani
1.1 Introduction 1
1.2 General Anatomy of the Mitral Valve 1
1.2.1 Mitral Annulus 1
1.2.2 Leaflets 3
1.2.3 Chordae Tendineae and Papillary Muscles 5
1.2.4 Papillary Muscles and Left Ventricle 5
1.3 Pathology of Mitral Valve 5
1.3.1 Mitral Valve Stenosis 5
1.3.2 Aging Changes and Mitral Annulus Calcification (MAC) 6
1.3.3 Acute Mitral Regurgitation 8
1.3.4 Chronic Mitral Regurgitation 8
1.3.5 Degenerative MR; Myxomatous Degeneration of the Mitral Valve 8
1.3.6 Functional MR 10
References 11
2 The Importance of Minimally Invasive Approaches for Mitral Valve Repair 15
Bobby Yanagawa and Niv Ad
2.1 Introduction to Minimally Invasive Mitral Valve Surgery 15
2.2 The Importance of MICS MVS 16
2.3 Patient Selection 17
2.4 Surgical Setup--Fibrillating Heart MVS 18
2.5 Alternatives for Cannulation 19
2.6 Alternatives to Myocardial Protection 19
2.7 Mitral Valve Repair 20
2.8 Outcomes 20
2.9 Initiating Minimally Invasive Mitral Valve Repair Program 21
2.10 Conclusion 22
References 22
3 When to Intervene--Should Surgical Guidelines Apply to Transcatheter Techniques in Treating Mitral
Regurgitation? 25
Samir Kapadia, Rishi Puri, Kinjal Banerjee, and Lars G. Svensson
3.1 Introduction 25
3.2 Primary MR 25
3.2.1 Current Guideline Recommendations 25
3.2.2 Transcatheter Therapies--New Guideline Applications? 26
3.3 Secondary MR 29
3.3.1 Current Guideline Recommendations 29
3.4 Conclusions 31
References 32
4 Transcatheter Mitral Valve Therapies: A Three-Dimensional Echocardiographic View 35
Shmuel Schwartzenberg, Chaim Yosefy, and Alexander Sagie
4.1 Introduction 35
4.1.1 Mitral Valve Anatomy 35
4.1.2 Mitral Valve Structure and Function 35
4.1.3 Mitral Regurgitation Severity 36
4.1.4 Diagnosis of MR Severity: Proximal Isovelocity Surface Area Method 36
4.1.5 Diagnosis of MR Severity: Vena Contracta Method 37
4.1.6 Primary and Secondary MR 37
4.1.7 Mitral Regurgitation and Cardiovascular Death and Morbidity 38
4.1.8 Screening for MitraClip Suitability 40
4.1.9 MitraClip Procedure Guidance 41
4.1.10 Transseptal Puncture 41
4.1.11 MitraClip Delivery Guidance 42
4.1.12 Adequacy of MitraClip Implantation Assessment 43
4.1.13 Other Technologies 45
4.2 Conclusions 45
References 45
5 CMR Assessment of Mitral Regurgitation 51
Daniel Knight and Vivek Muthurangu
5.1 Introduction 51
5.2 Pulse Sequences Used in CMR 52
5.2.1 Cine Imaging 52
5.2.2 Phase Contrast Imaging 52
5.3 Assessment of MR Severity 52
5.3.1 Qualitative Assessment 52
5.3.2 Quantitative Assessment 55
5.3.3 Technical Considerations for the Quantitative Assessment of MR by CMR 56
5.4 Identification of MR Etiology 57
5.4.1 Primary MR 57
5.4.2 Secondary MR 57
5.5 The Role of CMR Assessment of MR in Clinical Practice 58
5.6 Conclusions 58
References 58
6 CT Planning for TMVR and Predicting LVOT Obstruction 63
Dee Dee Wang, Mayra Guerrero, Brian O'Neill, Pedro A. Villablanca Spinetto, James Lee, Tiberio Frisoli, Marvin Eng, and William O'Neill
6.1 Introduction 63
6.2 History of Imaging for Mitral Valve Disease 63
6.2.1 TAVR CT Planning 63
6.2.2 Surgical and Transcatheter Mitral Interventions 63
6.3 Concept of Aortic and Mitral Valve Technology Development 64
6.4 Basics of CT Imaging Acquisition 66
6.5 Definition of Mitral Valve and TMVR device Landing Zone 66
6.6 Definition of LVOT 66
6.7 CT Methods for Neo-LVOT prediction modeling 67
6.8 CT Validation of Neo-LVOT Prediction Modeling Post-TMVR 68
6.9 Correlation Between Pre- and Post-TMVR CT Neo-LVOT Prediction Modeling 69
6.10 What Else Has CT Planning for TMVR Taught Us? 70
Acknowledgments 72
References 72
7 General Principles and State-of-the-Art Echocardiographic Evaluation of the Mitral Valve 75
Federico M. Asch and Diego Medvedofsky
7.1 Introduction 75
7.2 Mechanism and Etiology of Chronic MR 75
7.2.1 Transthoracic Echocardiography 76
7.2.1.1 Assessment of MR Severity 76
7.2.2 Qualitative Assessment 76
7.2.2.1 Color Flow Doppler 76
7.3 Continuous Wave (CW) Density Jet 79
7.3.1 Semi-Quantitative Assessment 79
7.3.1.1 VC Width 79
7.4 Pulmonary Vein Flow/Mitral Inflow 79
7.4.1 Quantitative Assessment 80
7.5 Selection of Best Candidates for Interventions of the Mitral Valve 82
7.5.1 Echocardiographic Criteria of COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) Trial 84
References 84
8 Intraprocedural Echocardiography for MitraClip 87
Philip Haines and Sumbal A. Janjua
8.1 Introduction 87
8.2 Pre-Procedure Evaluation 88
8.3 Importance of the Baseline Study - TEE 88
8.4 The Transseptal Puncture 95
8.5 Guiding MitraClip System to Mitral Valve 98
8.6 Intraprocedural Guidance of Clip within Mitral Valve and Leaflets 102
8.7 Post-Clip-Deployment Assessment of Mitral Valve Function 103
8.8 Assessment of Complications and Iatrogenic ASD 105
References 112
9 Intraprocedural Echocardiography for Transcatheter Mitral Valve Replacement 115
Patrick T. Gleason, John C. Lisko, and Stamatios Lerakis
9.1 Introduction 115
9.2 Baseline Mitral Valve Assessment 115
9.3 Access to the Left Atrium, Left Ventricle, and Mitral Valve 116
9.4 Predeployment and Deployment Monitoring 118
9.5 Postdeployment Evaluation 120
References 122
10 Transcatheter Repair: MitraClip for Degenerative Mitral Regurgitation 125
Ted Feldman
10.1 Surgery for Degenerative Mitral Regurgitation 125
10.2 Evidence Base for MitraClip 125
10.3 Challenges for the MitraClip Procedure 130
10.4 Evaluation of MitraClip for Less than Prohibitive-Risk DMR Patients 131
10.5 Future Directions for MitraClip and Alternative Approaches for Leaflet Repair 133
10.6 Summary 135
References 136
11 MitraClip(TM) for Secondary Mitral Regurgitation 139
Brian J. Forrestal and Toby Rogers
11.1 Introduction 139
[...]opean and US Clinical Practice Guidelines 139
11.3 The MitraClip System 140
11.4 MitraClip Preprocedural Planning 140
11.5 Surgical Outcomes Data 140
11.6 The COAPT and MITRA-FR Trials 141
11.7 Summary and Conclusions 144
References 144
12 The Edwards PASCAL Transcatheter Valve Repair System 147
Mirjam Winkel, Stephan Windecker, and Fabien Praz
12.1 Introduction 147
12.2 The Edwards PASCAL(TM) Transcatheter Valve Repair System 147
12.3 Implantation Procedure 148
12.4 Compassionate-Use and Early Feasibility Data 150
12.5 Future Developments 151
References 152
13 The Development of a Novel Percutaneous Treatment for Secondary Mitral Regurgitation--The Carillon(r) Mitral Contour System(r) 153
Steven L. Goldberg
13.1 Introduction 153
13.2 REDUCE-FMR 157
13.3 The CARILLON Trial 160
13.4 Summary 161
References 161
14 A Fully Percutaneous Mitral Ring: The Cardioband System 163
Antonio Mangieri, Enrico Poletti, and Azeem Latib
14.1 Introduction 163
14.2 Mitral Annulus Anatomy 163
14.3 Pathophysiological Role of the Mitral Annulus in Mitral Regurgitation 164
14.3.1 Mitral Annulus in FMR 164
14.3.2 Mitral Annulus in DMR 164
14.4 Surgical Annuloplasty in Mitral Regurgitation 164
14.5 The Cardioband System: Description of the Device 165
14.6 Procedural Planning 165
14.7 Clinical Studies 168
14.8 Possible Complications Related to the Implantation of Cardioband 170
14.9 Recurrence of Mitral Regurgitation Following Cardioband Implantation 171
14.10 Cardioband in Combination with Other Devices 172
14.11 Conclusions 173
References 173
15 Transcatheter Mitral Cerclage Annuloplasty 175
Christopher Bruce, June-Hong Kim, Toby Rogers, and Robert J. Lederman
15.1 Introduction 175
15.2 Cerclage Anatomy and Function 175
15.3 Limitations of Coronary Sinus Annuloplasty 176
15.4 Cerclage Annuloplasty Device 177
15.5 The Cerclage Procedure 177
15.6 Preclinical Experiments 178
15.7 Initial Human Experience 178
15.8 Future Directions 180
15.9 Summary 182
Competing Interests 183
References 183
16 The Transapical Off-Pump Mitral Valve Repair with the NeoChord Implantation (TOP-MINI) 185
Stefan Bertog, Laura Vaskelyte, Nalan Schnelle, Iris Grunwald, Ilona Hofmann, Sameer Gafoor, Markus Reinartz, Predrag Matic, Bojan Jovanovic, Kolja Sievert, Michèle Jaqueline Lembens, and Horst Sievert
16.1 Introduction 185
16.2 Technology 185
16.3 Patient Selection 186
16.4 Procedure 186
16.5 Echocardiographic Guidance 191
16.6 Examples 191
16.6.1 Ideal Anatomy 191
16.6.2 Acceptable Anatomy 191
16.6.3 Challenging Anatomy 192
16.6.4 Data 192
16.7 Conclusion 194
References 195
17 AltaValve(TM)--A Transcatheter Mitral Valve Regurgitation Treatment Technology 197
Katherine Kumar, PhD and Saravana Kumar, PhD
17.1 Clinical Need 197
17.2 Device Description 198
17.2.1 Principle of Operation 198
17.2.2 Device Construction 199
17.2.2.1 Stent 200
17.2.2.2 Stent Cap 200
17.2.2.3 Tissue Valve 200
17.2.2.4 Fabric Skirts and Sutures 200
17.2.3 Delivery Systems 200
17.3 Anatomical Imaging and Sizing 202
17.4 Preclinical and Clinical Experience 203
17.4.1 Animal Studies 203
17.5 Human Clinical Experience 204
17.6 Summary 205
References 206
18 The ARTO Transcatheter Mitral Valve Repair System 209
Andrejs Erglis, Inga Narbute, Agnese Strenge, and Samantha E. Greene
18.1 Device Description 209
18.2 Procedural Details 209
18.3 Clinical Experience with the ARTO System 212
18.4 Unique Features of the ARTO System 216
References 216
19 Transcatheter Mitral Annuloplasty: The Millipede Device 219
Jason H. Rogers and Steven F. Bolling
19.1 Background 219
19.2 The Millipede Device 219
19.3 Millipede Implantation Procedure 220
19.4 Surgical Millipede Implants 220
19.5 Millipede Clinical Results 222
19.6 Clinical Implications 223
19.7 Summary 226
Author Disclosures 226
References 226
20 Transapical and Transseptal Access for Transcatheter Mitral Valve Replacement: Techniques and Devices 227
James Edelman and Vinod...
Details
| Erscheinungsjahr: | 2021 |
|---|---|
| Fachbereich: | Allgemeine Lexika |
| Genre: | Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Buch |
| Seiten: | 400 |
| Inhalt: | 400 S. |
| ISBN-13: | 9781119490685 |
| ISBN-10: | 1119490685 |
| Sprache: | Englisch |
| Herstellernummer: | 1W119490680 |
| Einband: | Gebunden |
| Redaktion: |
Waksman, Ron
Rogers, Toby |
| Herausgeber: | Ron Waksman/Toby Rogers |
| Hersteller: | Wiley |
| Maße: | 257 x 188 x 28 mm |
| Von/Mit: | Ron Waksman (u. a.) |
| Erscheinungsdatum: | 24.05.2021 |
| Gewicht: | 1,021 kg |
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