PART I Common Problems
1 Sudden Deterioration in Neurologic Status
2 Agitation and Delirium
3 Management of Acute Pain in the Intensive Care Unit
4 Fever and Hyperthermia
5 Very High Systemic Arterial Blood Pressure
6 Low Systemic Arterial Blood Pressure
7 Tachycardia and Bradycardia
8 Arterial Hypoxemia
9 Acute Respiratory Failure
10 Hyperbaric Oxygen in Critical Care
11 Pulmonary Edema
12 Pleural Effusion in the Intensive Care Unit
13 Polyuria
14 Oliguria
15 Metabolic Acidosis and Alkalosis
16 Hyperkalemia and Hypokalemia
17 Hyperphosphatemia and Hypophosphatemia
18 Hypomagnesemia
19 Hypocalcemia and Hypercalcemia
20 Disorders of Glucose Control or Blood Glucose Disorders
21 Anemia
22 Coagulopathy in the Intensive Care Unit
23 Jaundice
24 Ascites
25 Acute Abdominal Pain
26 Ileus in Critical Illness
27 Diarrhea
28 Chest Pain
29 Biochemical or Electrocardiographic Evidence of Acute Myocardial Injury
PART II Common Approaches for Organ Support, Diagnosis, and Monitoring
30 Point-of-Care Ultrasound
31 Echocardiography
32 Cardiovascular Monitoring
33 Bedside Monitoring of Pulmonary Function
34 Arterial Blood Gas Interpretation
35 Tracheal Intubation
36 Tracheostomy
37 Basic Principles of Mechanical Ventilation
38 Basic Principles of Renal Replacement Therapy
39 Target Temperature Management in Critically Ill Patients
40 Extracorporeal Membrane Oxygenation (Venovenous and Venoarterial ECMO)
41 Nutritional Support
PART III Central Nervous System
42 Advanced Bedside Neuromonitoring
43 Coma
44 Use of Brain Injury Biomarkers in Critical Care Settings
45 Cardiopulmonary Cerebral Resuscitation
46 Management of Acute Ischemic Stroke
47 Nontraumatic Intracerebral and Subarachnoid Hemorrhage
48 Seizures in the Critically Ill
49 Neuromuscular Disorders in the Critically Ill
50 Traumatic Brain Injury
51 Spinal Cord Injury
52 Neuroimaging
PART IV Pulmonary
53 Core Principles of Respiratory Physiology and Pathophysiology in Critical Illness
54 Patient-Ventilator Interaction
55 Noninvasive Positive-Pressure Ventilation
56 Advanced Techniques in Mechanical Ventilation
57 Weaning from Mechanical Ventilation
58 Adjunctive Respiratory Therapy
59 Intensive Care Unit Imaging
60 Acute Respiratory Distress Syndrome
61 Drowning
62 Aspiration Pneumonitis and Pneumonia
63 Severe Asthma Exacerbation in Adults
64 Chronic Obstructive Pulmonary Disease
65 Pulmonary Embolism
66 Pneumothorax
67 Community-Acquired Pneumonia
68 Nosocomial Pneumonia
PART V Cardiovascular
69 Core Principles of Cardiovascular Physiology and Pathophysiology in Critical Illness
70 Acute Coronary Syndromes: Therapy
71 Supraventricular Arrhythmias
72 Ventricular Arrhythmias
73 Conduction Disturbances and Cardiac Pacemakers
74 Myocarditis and Acute Myopathies
75 Pericardial Diseases
76 Emergency Heart Valve Disorders
77 Pulmonary Hypertension and Right Ventricular Failure
78 Hypertensive Crisis: Emergency and Urgency
79 Pathophysiology and Classification of Shock States
80 Resuscitation From Circulatory Shock
81 Inotropic Therapy
82 Mechanical Support in Cardiogenic Shock
PART VI Gastrointestinal
83 Portal Hypertension: Critical Care Considerations
84 Hepatorenal Syndrome
85 Hepatopulmonary Syndrome
86 Hepatic Encephalopathy
87 Acute Liver Failure
88 Calculous and Acalculous Cholecystitis
89 Acute Pancreatitis
90 Abdominal Sepsis
91 Mechanical Bowel Obstruction
92 Toxic Megacolon and Ogilvie's Syndrome
93 Severe Gastrointestinal Bleeding
PART VII Renal
94 Core Principles of Renal Physiology and Pathophysiology in Critical Illness
95 Clinical Assessment of Renal Function
96 Biomarkers of Acute Kidney Injury
97 Water Metabolism
98 Advanced Techniques in Blood Purification
99 Fluid and Volume Therapy in the ICU
100 Acute Kidney Injury
101 Urinary Tract Obstruction
102 Contrast-Induced Acute Kidney Injury
103 Glomerulonephritis
104 Interstitial Nephritis
PART VIII Infectious Diseases
105 Antimicrobial Stewardship
106 Prevention and Control of Nosocomial Pneumonia
107 Antimicrobial Agents With Primary Activity Against Gram-Negative Bacteria
108 Antimicrobial Agents With Primary Activity Against Gram-Positive Bacteria
109 Antimicrobial Agents Active Against Anaerobic Bacteria
110 Selective Decontamination of the Digestive Tract
111 Intravascular Catheter-Related Infections
112 Septic Shock
113 Infections of the Urogenital Tract
114 Central Nervous System Infections
115 Infections of Skin, Muscle, and Necrotizing Soft Tissue Infections
116 Head and Neck Infections
117 Infectious Endocarditis
118 Fungal Infections
119 Influenza and Acute Viral Syndromes
120 Human Immunodeficiency Virus Infection
121 Infections in the Immunocompromised Patient
122 Tuberculosis
123 Malaria and Other Tropical Infections in the Intensive Care Unit
124 Clostridioides difficile Infection
PART IX Hematology
125 Anemia and RBC Transfusion
126 Guidelines for Blood Component Therapy
127 Venous Thromboembolism
128 Anticoagulation in the Intensive Care Unit
129 Monitoring of Coagulation Status
130 Critical Care of the Hematopoietic Stem Cell Transplant Recipient
PART X Obstetrics
131 Cardiovascular and Endocrinologic Changes Associated With Pregnancy
132 Hypertensive Disorders in Pregnancy
133 Acute Pulmonary Complications During Pregnancy
134 Postpartum Hemorrhage
PART XI Endocrine
135 Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State
136 Adrenal Insufficiency
137 Thyroid Disorders
138 Diabetes Insipidus
PART XII Pharmacology and Toxicology
139 General Principles of Pharmacokinetics and Pharmacodynamics
140 Poisoning: Overview of Approaches for Evaluation and Treatment
PART XIII Surgery/Trauma
141 Resuscitation of Hypovolemic Shock
142 Mediastinitis
143 Epistaxis
144 Management of the Postoperative Cardiac Surgical Patient
145 Intensive Care Unit Management of Lung Transplant Patients
146 Perioperative Management of the Liver Transplant Patient
147 Intestinal and Multivisceral Transplantation: The Ultimate Treatment for Intestinal Failure
148 Aortic Dissection
149 Mesenteric Ischemia
150 Abdominal Compartment Syndrome
151 Extremity Compartment Syndromes
152 Thromboembolization and Thrombolytic Therapy
153 Atheroembolization
154 Pressure Ulcers
155 Burns, Including Inhalation Injury
156 Thoracic Trauma
157 Abdominal Trauma
158 Pelvic Fractures and Long Bone Fractures
159 Determination of Brain Death and Management of the Brain-Dead Organ Donor
160 Donation After Cardiac Death (Non-Heart-Beating Donation)
PART XIV Ethical and End-of-Life Issues
161 Conversations With Families of Critically Ill Patients
162 Resource Allocation in the Intensive Care Unit
163 Basic Ethical Principles in Critical Care
PART XV Organization and Management
164 Building Teamwork to Improve Outcomes
165 Severity of Illness Indices and Outcome Prediction
166 Long-Term Outcomes of Critical Illness
167 Early Ambulation in the ICU
168 Mass Critical Care
169 Telemedicine in Intensive Care
170 Teaching Critical Care
Online Chapters
E1 Difficult Airway Management for Intensivists, 1370.e1
E2 Bedside Ultrasonography, 1370.e36
E3 Central Venous Catheterization, 1370.e67
E4 Arterial Cannulation and Invasive Blood Pressure Measurement, 1370.e71
E5 Bedside Pulmonary Artery Catheterization, 1370.e80
E6 Cardioversion and Defibrillation, 1370.e83
E7 Transvenous and Transcutaneous Cardiac Pacing, 1370.e85
E8 Ventricular Assist Device Implantation, 1370.e87
E9 Pericardiocentesis, 1370.e90
E10 Paracentesis and Diagnostic Peritoneal Lavage, 1370.e95
E11 Thoracentesis, 1370.e99
E12 Chest Tube Placement, Care, and Removal, 1370.e101
E13 Fiber-Optic Bronchoscopy, 1370.e105
E14 Bronchoalveolar Lavage and Protected Specimen Bronchial Brushing, 1370.e111
E15 Percutaneous Dilatational Tracheostomy, 1370.e114
E16 Esophageal Balloon Tamponade, 1370.e118
E17 Nasoenteric Feeding Tube Insertion, 1370.e120
E18 Lumbar Puncture, 1370.e122
E19 Jugular Venous and Brain Tissue Oxygen Tension Monitoring, 1370.e124
E20 Intracranial Pressure Monitoring, 1370.e130
E21 Indirect Calorimetry, 1370.e133
E22 Extracorporeal Membrane Oxygenation Cannulation, 1370.e134
Index