Dekorationsartikel gehören nicht zum Leistungsumfang.
Sprache:
Englisch
178,50 €*
Versandkostenfrei per Post / DHL
Aktuell nicht verfügbar
Kategorien:
Beschreibung
The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updated
Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism.
The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource:
* Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science
* Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers
* Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics
* Presents a new companion website with useful supplementary materials at [...]
Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.
Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism.
The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource:
* Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science
* Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers
* Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics
* Presents a new companion website with useful supplementary materials at [...]
Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.
The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updated
Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism.
The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource:
* Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science
* Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers
* Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics
* Presents a new companion website with useful supplementary materials at [...]
Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.
Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism.
The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource:
* Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science
* Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers
* Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics
* Presents a new companion website with useful supplementary materials at [...]
Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.
Über den Autor
John P. Bilezikian is the Dorothy L. and Daniel H. Silberberg Professor of Medicine and Professor of Pharmacology at the College of Physicians & Surgeons, Columbia University. He is Chief Emeritus of the Division of Endocrinology and Vice-chair of the Department of Medicine for International Research and Education. He is also Director Emeritus of the Metabolic Bone Diseases Program at Columbia University Medical Center.
Inhaltsverzeichnis
Contributors xi Preface to the Ninth Edition of the Primer:
John P. Bilezikian xxiv About ASBMR xxv President's Preface Michael J. Econs xxvi About the Companion Website xxvii Section I Molecular and Cellular Determinants of Bone Structure and Function 1Section Editor Karen Lyons 1 Early Skeletal Morphogenesis in Embryonic Development 3
Yingzi Yang 2 Endochondral Ossification 12
Courtney M. Karner and Matthew J. Hilton 3 Local and Circulating Osteoprogenitor Cells and Lineages 20
Naomi Dirckx and Christa Maes 4 Osteoblasts Function, Development, and Regulation 31
Elizabeth W. Bradley, Jennifer J. Westendorf, Andre J. van Wijnen, and Amel Dudakovic 5 Osteocytes 38
Lynda F. Bonewald 6 Osteoclast Biology and Bone Resorption 46
Hiroshi Takayanagi 7 Signal Transduction Cascades Controlling Osteoblast Differentiation 54
David J.J. de Gorter, Gonzalo Sánchez¿Duffhues, and Peter ten Dijke 8 The TGF¿ß Superfamily in Bone Formation and Maintenance 60
Ce Shi and Yuji Mishina 9 Recent Developments in Understanding the Role of Wnt Signaling in Skeletal Development and Disease 68
Zhendong A. Zhong, Nicole J. Ethen, and Bart O. Williams 10 Mechanotransduction in Bone Formation and Maintenance 75
Whitney A. Bullock, Lilian I. Plotkin, Alexander G. Robling, and Fredrick M. Pavalko 11 The Composition of Bone 84
Adele L. Boskey and Pamela G. Robey 12 Assessment of Bone Mass, Structure, and Quality in Rodents 93
Jeffry S. Nyman and Deepak Vashishth 13 Skeletal Healing Cellular and Molecular Determinants 101
Alayna E. Loiselle and Michael J. Zuscik 14 Biomechanics of Fracture Healing 108
Elise F. Morgan, Amira I. Hussein, and Thomas A. Einhorn Section II Skeletal Physiology 115Section Editor Ego Seeman 15 Human Fetal and Neonatal Bone Development 117
Tao Yang, Monica Grover, Kyu Sang Joeng, and Brendan Lee 16 Skeletal Growth a Major Determinant of Bone's Structural Diversity in Women and Men 123
Ego Seeman 17 Racial Differences in the Acquisition and Age¿related Loss of Bone Strength 131
Shane A. Norris, Marcella D. Walker, Kate Ward, Lisa K. Micklesfield, and John M. Pettifor 18 Calcium, Vitamin D, and Other Nutrients During Growth 135
Tania Winzenberg and Graeme Jones 19 Mechanical Loading and the Developing Skeleton 141
Mark R. Forwood 20 Pregnancy and Lactation 147
Christopher S. Kovacs and Henry M. Kronenberg 21 Menopause and Age¿related Bone Loss 155
Carlos M. Isales and Ego Seeman Section III Mineral Homeostasis 163Section Editors David Goltzman and Harald Jüppner 22 Regulation of Calcium Homeostasis 165
Line Vautour and David Goltzman 23 Magnesium Homeostasis 173
Aliya Aziz Khan, Asiya Sbayi, and Karl Peter Schlingmann 24 Fetal Calcium Metabolism 179
Christopher S. Kovacs 25 FGF23 and the Regulation of Phosphorus Metabolism 187
Kenneth E. White and Michael J. Econs 26 Gonadal Steroids 194
Stavros C. Manolagas and Maria Schuller Almeida 27 Parathyroid Hormone 205
Thomas J. Gardella, Robert A. Nissenson, and Harald Jüppner 28 Parathyroid Hormone¿Related Protein 212
John J. Wysolmerski and T. John Martin 29 Calcium¿Sensing Receptor 221
Geoffrey N. Hendy 30 Vitamin D Production, Metabolism, Action, and Clinical Requirements 230
Daniel D. Bikle, John S. Adams, and Sylvia Christakos Section IV Investigation of Metabolic Bone Diseases 241Section Editors Douglas C. Bauer and Klaus Engelke 31 Techniques of Bone Mass Measurement in Children with Risk Factors for Osteoporosis 243
Nicola J. Crabtree and Leanne M. Ward 32 Standard Techniques of Bone Mass Measurement in Adults 252
E. Michael Lewiecki, Paul D. Miller, and Nelson B. Watts 33 Advanced Techniques of Bone Mass Measurements and Strength in Adults 260
Kyle K. Nishiyama, Enrico Dall'Ara, and Klaus Engelke 34 Magnetic Resonance Imaging of Bone 272
Sharmila Majumdar 35 Trabecular Bone Score 277
Barbara C. Silva and William D. Leslie 36 Reference Point Indentation 287
Adolfo Diez¿Perez and Joshua N. Farr 37 Biochemical Markers of Bone Turnover in Osteoporosis 293
Pawel Szulc, Douglas C. Bauer, and Richard Eastell 38 Scintigraphy and PET in Metabolic Bone Disease 302
Lorenzo Nardo, Paola A. Erba, and Benjamin L. Franc 39 Bone Histomorphometry in Clinical Practice 310
Robert R. Recker and Carolina Aguiar Moreira 40 Diagnosis and Classification of Vertebral Fracture 319
James F. Griffith and Harry K. Genant 41 FRAX Assessment of Fracture Risk 331
John A. Kanis, Eugene V. McCloskey, Nicholas C. Harvey, and William D. Leslie Section V Genetics of Bone 341Section Editor Rajesh V. Thakker 42 Introduction to Genetics 343
Paul J. Newey, Michael P. Whyte, and Rajesh V. Thakker 43 Animal Models Genetic Manipulation 351
Karen Lyons 44 Animal Models Allelic Determinants for Bone Mineral Density 359
J. H. Duncan Bassett, Graham R. Williams, and Robert D. Blank 45 Transcriptional Profiling for Genetic Assessment 367
Aimy Sebastian and Gabriela G. Loots 46 Approaches to Genetic Testing 373
Christina Jacobsen, Yiping Shen, and Ingrid A. Holm 47 Human Genome¿Wide Association Studies 378
Douglas P. Kiel, Emma L. Duncan, and Fernando Rivadeneira 48 Translational Genetics of Osteoporosis From Population Association to Individualized Assessment 385
Bich Tran, Jacqueline R. Center, and Tuan V. Nguyen Section VI Osteoporosis 393Section Editors Paul D. Miller, Socrates E. Papapoulos, and Michael R. McClung 49 Osteoporosis an Overview 395
Michael R. McClung, Paul D. Miller, and Socrates E. Papapoulos 50 The Epidemiology of Osteoporotic Fractures 398
Nicholas C. Harvey, Elizabeth M. Curtis, Elaine M. Dennison, and Cyrus Cooper 51 Fracture Liaison Service 405
Piet Geusens, John A. Eisman, Andrea Singer, and Joop van den Bergh 52 Sex Steroids and the Pathogenesis of Osteoporosis 412
Matthew T. Drake and Sundeep Khosla 53 Juvenile Osteoporosis 419
Francis H. Glorieux and Craig Munns 54 Transplantation Osteoporosis 424
Peter R. Ebeling 55 Premenopausal Osteoporosis 436
Adi Cohen and Elizabeth Shane 56 Osteoporosis in Men 443
Eric S. Orwoll and Robert A. Adler 57 Bone Stress Injuries 450
Stuart J. Warden and David B. Burr 58 Inflammation¿Induced Bone Loss in the Rheumatic Diseases 459
Ellen M. Gravallese and Steven R. Goldring 59 Glucocorticoid¿Induced Osteoporosis 467
Kenneth Saag and Robert A. Adler 60 Human Immunodeficiency Virus and Bone 474
Michael T. Yin and Todd T. Brown 61 Effects on the Skeleton from Medications Used to Treat Nonskeletal Disorders 482
Nelson B. Watts 62 Diabetes and Fracture Risk 487
Serge Ferrari, Nicola Napoli, and Ann Schwartz 63 Obesity and Skeletal Health 492
Juliet Compston 64 Sarcopenia and Osteoporosis 498
Gustavo Duque and Neil Binkley 65 Management of Osteoporosis in Patients with Chronic Kidney Disease 505
Paul D. Miller 66 Other Secondary Causes of Osteoporosis 510
Neveen A. T. Hamdy and Natasha M. Appelman¿Dijkstra 67 Exercise for Osteoporotic Fracture Prevention and Management 517
Robin M. Daly and Lora Giangregorio 68 Prevention of Falls 526
Heike A. Bischoff¿Ferrari 69 Nutritional Support for Osteoporosis 534
Connie M. Weaver, Bess Dawson¿Hughes, Rene Rizzoli, and Robert P. Heaney 70 Estrogens, Selective Estrogen Receptor Modulators, and Tissue¿Selective Estrogen Complex 541
Tobias J. de Villiers 71 Bisphosphonates for Postmenopausal Osteoporosis 545
Andrea Giusti and Socrates E. Papapoulos 72 Denosumab 553
Aline Granja Costa, E. Michael Lewiecki, and John P. Bilezikian 73 Parathyroid Hormone and Abaloparatide Treatment for Osteoporosis 559
Felicia Cosman and Susan L. Greenspan 74 Combination Anabolic and Antiresorptive Therapy for Osteoporosis 567
Joy N. Tsai and Benjamin Z. Leder 75 Strontium Ranelate and Calcitonin 573
Leonardo Bandeira and E. Michael Lewiecki 76 Adverse Effects of Drugs for Osteoporosis 579
Bo Abrahamsen and Daniel PrietöAlhambra 77 Orthopedic Principles of Fracture Management 588
Manoj Ramachandran and David G. Little 78 Adherence to Osteoporosis Therapies 593
Stuart L. Silverman and Deborah T. Gold 79 Cost¿Effectiveness of Osteoporosis Treatment 597
Anna N.A. Tosteson 80 Future Therapies 603
Michael R. McClung Section VII Metabolic Bone Diseases 611Section Editors Suzanne M. Jan de Beur and Peter R. Ebeling 81 Approach to Parathyroid Disorders 613
John P. Bilezikian 82 Primary Hyperparathyroidism 619
Shonni J. Silverberg, Francisco Bandeira, Jianmin Liu, Claudio Marcocci, and Marcella D. Walker 83 Familial States of Primary Hyperparathyroidism 629
Andrew Arnold, Sunita K. Agarwal, and Rajesh V. Thakker 84 Non¿Parathyroid Hypercalcemia 639
Mara J. Horwitz 85 Hypocalcemia Definition, Etiology, Pathogenesis, Diagnosis, and Management 646
Anne L. Schafer and Dolores M. Shoback 86 Hypoparathyroidism 654
Tamara Vokes, Mishaela R. Rubin, Karen K. Winer, Michael Mannstadt, Natalie E. Cusano, Harald Jüppner, and John P. Bilezikian 87 Pseudohypoparathyroidism 661
Agnès Linglart, Michael A. Levine, and Harald Jüppner 88 Disorders of Phosphate Homeostasis 674
Mary D. Ruppe and Suzanne M. Jan de Beur 89 Rickets and Osteomalacia 684
Michaël R. Laurent, Nathalie Bravenboer, Natasja M. Van Schoor, Roger Bouillon, John M. Pettifor, and Paul Lips 90 Pathophysiology and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder 695
Mark R. Hanudel, Sharon M. Moe, and Isidro B. Salusky 91 Disorders of Mineral Metabolism in Childhood 705
Thomas O. Carpenter and Nina S. Ma 92 Paget Disease of Bone 713
Julia F. Charles, Ethel S. Siris, and G. David Roodman 93 Epidemiology, Diagnosis, Evaluation, and Treatment of Nephrolithiasis 721
Murray J. Favus and David A. Bushinsky 94 Immobilization and Burns Other Conditions Associated with Osteoporosis 730
William A. Bauman, Christopher Cardozo, and Gordon L. Klein Section VIII Cancer and Bone 737Section Editors Theresa Guise and G. David...
John P. Bilezikian xxiv About ASBMR xxv President's Preface Michael J. Econs xxvi About the Companion Website xxvii Section I Molecular and Cellular Determinants of Bone Structure and Function 1Section Editor Karen Lyons 1 Early Skeletal Morphogenesis in Embryonic Development 3
Yingzi Yang 2 Endochondral Ossification 12
Courtney M. Karner and Matthew J. Hilton 3 Local and Circulating Osteoprogenitor Cells and Lineages 20
Naomi Dirckx and Christa Maes 4 Osteoblasts Function, Development, and Regulation 31
Elizabeth W. Bradley, Jennifer J. Westendorf, Andre J. van Wijnen, and Amel Dudakovic 5 Osteocytes 38
Lynda F. Bonewald 6 Osteoclast Biology and Bone Resorption 46
Hiroshi Takayanagi 7 Signal Transduction Cascades Controlling Osteoblast Differentiation 54
David J.J. de Gorter, Gonzalo Sánchez¿Duffhues, and Peter ten Dijke 8 The TGF¿ß Superfamily in Bone Formation and Maintenance 60
Ce Shi and Yuji Mishina 9 Recent Developments in Understanding the Role of Wnt Signaling in Skeletal Development and Disease 68
Zhendong A. Zhong, Nicole J. Ethen, and Bart O. Williams 10 Mechanotransduction in Bone Formation and Maintenance 75
Whitney A. Bullock, Lilian I. Plotkin, Alexander G. Robling, and Fredrick M. Pavalko 11 The Composition of Bone 84
Adele L. Boskey and Pamela G. Robey 12 Assessment of Bone Mass, Structure, and Quality in Rodents 93
Jeffry S. Nyman and Deepak Vashishth 13 Skeletal Healing Cellular and Molecular Determinants 101
Alayna E. Loiselle and Michael J. Zuscik 14 Biomechanics of Fracture Healing 108
Elise F. Morgan, Amira I. Hussein, and Thomas A. Einhorn Section II Skeletal Physiology 115Section Editor Ego Seeman 15 Human Fetal and Neonatal Bone Development 117
Tao Yang, Monica Grover, Kyu Sang Joeng, and Brendan Lee 16 Skeletal Growth a Major Determinant of Bone's Structural Diversity in Women and Men 123
Ego Seeman 17 Racial Differences in the Acquisition and Age¿related Loss of Bone Strength 131
Shane A. Norris, Marcella D. Walker, Kate Ward, Lisa K. Micklesfield, and John M. Pettifor 18 Calcium, Vitamin D, and Other Nutrients During Growth 135
Tania Winzenberg and Graeme Jones 19 Mechanical Loading and the Developing Skeleton 141
Mark R. Forwood 20 Pregnancy and Lactation 147
Christopher S. Kovacs and Henry M. Kronenberg 21 Menopause and Age¿related Bone Loss 155
Carlos M. Isales and Ego Seeman Section III Mineral Homeostasis 163Section Editors David Goltzman and Harald Jüppner 22 Regulation of Calcium Homeostasis 165
Line Vautour and David Goltzman 23 Magnesium Homeostasis 173
Aliya Aziz Khan, Asiya Sbayi, and Karl Peter Schlingmann 24 Fetal Calcium Metabolism 179
Christopher S. Kovacs 25 FGF23 and the Regulation of Phosphorus Metabolism 187
Kenneth E. White and Michael J. Econs 26 Gonadal Steroids 194
Stavros C. Manolagas and Maria Schuller Almeida 27 Parathyroid Hormone 205
Thomas J. Gardella, Robert A. Nissenson, and Harald Jüppner 28 Parathyroid Hormone¿Related Protein 212
John J. Wysolmerski and T. John Martin 29 Calcium¿Sensing Receptor 221
Geoffrey N. Hendy 30 Vitamin D Production, Metabolism, Action, and Clinical Requirements 230
Daniel D. Bikle, John S. Adams, and Sylvia Christakos Section IV Investigation of Metabolic Bone Diseases 241Section Editors Douglas C. Bauer and Klaus Engelke 31 Techniques of Bone Mass Measurement in Children with Risk Factors for Osteoporosis 243
Nicola J. Crabtree and Leanne M. Ward 32 Standard Techniques of Bone Mass Measurement in Adults 252
E. Michael Lewiecki, Paul D. Miller, and Nelson B. Watts 33 Advanced Techniques of Bone Mass Measurements and Strength in Adults 260
Kyle K. Nishiyama, Enrico Dall'Ara, and Klaus Engelke 34 Magnetic Resonance Imaging of Bone 272
Sharmila Majumdar 35 Trabecular Bone Score 277
Barbara C. Silva and William D. Leslie 36 Reference Point Indentation 287
Adolfo Diez¿Perez and Joshua N. Farr 37 Biochemical Markers of Bone Turnover in Osteoporosis 293
Pawel Szulc, Douglas C. Bauer, and Richard Eastell 38 Scintigraphy and PET in Metabolic Bone Disease 302
Lorenzo Nardo, Paola A. Erba, and Benjamin L. Franc 39 Bone Histomorphometry in Clinical Practice 310
Robert R. Recker and Carolina Aguiar Moreira 40 Diagnosis and Classification of Vertebral Fracture 319
James F. Griffith and Harry K. Genant 41 FRAX Assessment of Fracture Risk 331
John A. Kanis, Eugene V. McCloskey, Nicholas C. Harvey, and William D. Leslie Section V Genetics of Bone 341Section Editor Rajesh V. Thakker 42 Introduction to Genetics 343
Paul J. Newey, Michael P. Whyte, and Rajesh V. Thakker 43 Animal Models Genetic Manipulation 351
Karen Lyons 44 Animal Models Allelic Determinants for Bone Mineral Density 359
J. H. Duncan Bassett, Graham R. Williams, and Robert D. Blank 45 Transcriptional Profiling for Genetic Assessment 367
Aimy Sebastian and Gabriela G. Loots 46 Approaches to Genetic Testing 373
Christina Jacobsen, Yiping Shen, and Ingrid A. Holm 47 Human Genome¿Wide Association Studies 378
Douglas P. Kiel, Emma L. Duncan, and Fernando Rivadeneira 48 Translational Genetics of Osteoporosis From Population Association to Individualized Assessment 385
Bich Tran, Jacqueline R. Center, and Tuan V. Nguyen Section VI Osteoporosis 393Section Editors Paul D. Miller, Socrates E. Papapoulos, and Michael R. McClung 49 Osteoporosis an Overview 395
Michael R. McClung, Paul D. Miller, and Socrates E. Papapoulos 50 The Epidemiology of Osteoporotic Fractures 398
Nicholas C. Harvey, Elizabeth M. Curtis, Elaine M. Dennison, and Cyrus Cooper 51 Fracture Liaison Service 405
Piet Geusens, John A. Eisman, Andrea Singer, and Joop van den Bergh 52 Sex Steroids and the Pathogenesis of Osteoporosis 412
Matthew T. Drake and Sundeep Khosla 53 Juvenile Osteoporosis 419
Francis H. Glorieux and Craig Munns 54 Transplantation Osteoporosis 424
Peter R. Ebeling 55 Premenopausal Osteoporosis 436
Adi Cohen and Elizabeth Shane 56 Osteoporosis in Men 443
Eric S. Orwoll and Robert A. Adler 57 Bone Stress Injuries 450
Stuart J. Warden and David B. Burr 58 Inflammation¿Induced Bone Loss in the Rheumatic Diseases 459
Ellen M. Gravallese and Steven R. Goldring 59 Glucocorticoid¿Induced Osteoporosis 467
Kenneth Saag and Robert A. Adler 60 Human Immunodeficiency Virus and Bone 474
Michael T. Yin and Todd T. Brown 61 Effects on the Skeleton from Medications Used to Treat Nonskeletal Disorders 482
Nelson B. Watts 62 Diabetes and Fracture Risk 487
Serge Ferrari, Nicola Napoli, and Ann Schwartz 63 Obesity and Skeletal Health 492
Juliet Compston 64 Sarcopenia and Osteoporosis 498
Gustavo Duque and Neil Binkley 65 Management of Osteoporosis in Patients with Chronic Kidney Disease 505
Paul D. Miller 66 Other Secondary Causes of Osteoporosis 510
Neveen A. T. Hamdy and Natasha M. Appelman¿Dijkstra 67 Exercise for Osteoporotic Fracture Prevention and Management 517
Robin M. Daly and Lora Giangregorio 68 Prevention of Falls 526
Heike A. Bischoff¿Ferrari 69 Nutritional Support for Osteoporosis 534
Connie M. Weaver, Bess Dawson¿Hughes, Rene Rizzoli, and Robert P. Heaney 70 Estrogens, Selective Estrogen Receptor Modulators, and Tissue¿Selective Estrogen Complex 541
Tobias J. de Villiers 71 Bisphosphonates for Postmenopausal Osteoporosis 545
Andrea Giusti and Socrates E. Papapoulos 72 Denosumab 553
Aline Granja Costa, E. Michael Lewiecki, and John P. Bilezikian 73 Parathyroid Hormone and Abaloparatide Treatment for Osteoporosis 559
Felicia Cosman and Susan L. Greenspan 74 Combination Anabolic and Antiresorptive Therapy for Osteoporosis 567
Joy N. Tsai and Benjamin Z. Leder 75 Strontium Ranelate and Calcitonin 573
Leonardo Bandeira and E. Michael Lewiecki 76 Adverse Effects of Drugs for Osteoporosis 579
Bo Abrahamsen and Daniel PrietöAlhambra 77 Orthopedic Principles of Fracture Management 588
Manoj Ramachandran and David G. Little 78 Adherence to Osteoporosis Therapies 593
Stuart L. Silverman and Deborah T. Gold 79 Cost¿Effectiveness of Osteoporosis Treatment 597
Anna N.A. Tosteson 80 Future Therapies 603
Michael R. McClung Section VII Metabolic Bone Diseases 611Section Editors Suzanne M. Jan de Beur and Peter R. Ebeling 81 Approach to Parathyroid Disorders 613
John P. Bilezikian 82 Primary Hyperparathyroidism 619
Shonni J. Silverberg, Francisco Bandeira, Jianmin Liu, Claudio Marcocci, and Marcella D. Walker 83 Familial States of Primary Hyperparathyroidism 629
Andrew Arnold, Sunita K. Agarwal, and Rajesh V. Thakker 84 Non¿Parathyroid Hypercalcemia 639
Mara J. Horwitz 85 Hypocalcemia Definition, Etiology, Pathogenesis, Diagnosis, and Management 646
Anne L. Schafer and Dolores M. Shoback 86 Hypoparathyroidism 654
Tamara Vokes, Mishaela R. Rubin, Karen K. Winer, Michael Mannstadt, Natalie E. Cusano, Harald Jüppner, and John P. Bilezikian 87 Pseudohypoparathyroidism 661
Agnès Linglart, Michael A. Levine, and Harald Jüppner 88 Disorders of Phosphate Homeostasis 674
Mary D. Ruppe and Suzanne M. Jan de Beur 89 Rickets and Osteomalacia 684
Michaël R. Laurent, Nathalie Bravenboer, Natasja M. Van Schoor, Roger Bouillon, John M. Pettifor, and Paul Lips 90 Pathophysiology and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder 695
Mark R. Hanudel, Sharon M. Moe, and Isidro B. Salusky 91 Disorders of Mineral Metabolism in Childhood 705
Thomas O. Carpenter and Nina S. Ma 92 Paget Disease of Bone 713
Julia F. Charles, Ethel S. Siris, and G. David Roodman 93 Epidemiology, Diagnosis, Evaluation, and Treatment of Nephrolithiasis 721
Murray J. Favus and David A. Bushinsky 94 Immobilization and Burns Other Conditions Associated with Osteoporosis 730
William A. Bauman, Christopher Cardozo, and Gordon L. Klein Section VIII Cancer and Bone 737Section Editors Theresa Guise and G. David...
Details
| Erscheinungsjahr: | 2018 |
|---|---|
| Fachbereich: | Allgemeines |
| Genre: | Biologie |
| Rubrik: | Naturwissenschaften & Technik |
| Thema: | Lexika |
| Medium: | Taschenbuch |
| Inhalt: | 1136 S. |
| ISBN-13: | 9781119266563 |
| ISBN-10: | 1119266564 |
| Sprache: | Englisch |
| Einband: | Kartoniert / Broschiert |
| Redaktion: | Bilezikian, John P. |
| Herausgeber: | John P Bilezikian |
| Auflage: | 9th edition |
| Hersteller: | Wiley |
| Maße: | 280 x 221 x 47 mm |
| Von/Mit: | John P. Bilezikian |
| Erscheinungsdatum: | 06.12.2018 |
| Gewicht: | 2,795 kg |
Über den Autor
John P. Bilezikian is the Dorothy L. and Daniel H. Silberberg Professor of Medicine and Professor of Pharmacology at the College of Physicians & Surgeons, Columbia University. He is Chief Emeritus of the Division of Endocrinology and Vice-chair of the Department of Medicine for International Research and Education. He is also Director Emeritus of the Metabolic Bone Diseases Program at Columbia University Medical Center.
Inhaltsverzeichnis
Contributors xi Preface to the Ninth Edition of the Primer:
John P. Bilezikian xxiv About ASBMR xxv President's Preface Michael J. Econs xxvi About the Companion Website xxvii Section I Molecular and Cellular Determinants of Bone Structure and Function 1Section Editor Karen Lyons 1 Early Skeletal Morphogenesis in Embryonic Development 3
Yingzi Yang 2 Endochondral Ossification 12
Courtney M. Karner and Matthew J. Hilton 3 Local and Circulating Osteoprogenitor Cells and Lineages 20
Naomi Dirckx and Christa Maes 4 Osteoblasts Function, Development, and Regulation 31
Elizabeth W. Bradley, Jennifer J. Westendorf, Andre J. van Wijnen, and Amel Dudakovic 5 Osteocytes 38
Lynda F. Bonewald 6 Osteoclast Biology and Bone Resorption 46
Hiroshi Takayanagi 7 Signal Transduction Cascades Controlling Osteoblast Differentiation 54
David J.J. de Gorter, Gonzalo Sánchez¿Duffhues, and Peter ten Dijke 8 The TGF¿ß Superfamily in Bone Formation and Maintenance 60
Ce Shi and Yuji Mishina 9 Recent Developments in Understanding the Role of Wnt Signaling in Skeletal Development and Disease 68
Zhendong A. Zhong, Nicole J. Ethen, and Bart O. Williams 10 Mechanotransduction in Bone Formation and Maintenance 75
Whitney A. Bullock, Lilian I. Plotkin, Alexander G. Robling, and Fredrick M. Pavalko 11 The Composition of Bone 84
Adele L. Boskey and Pamela G. Robey 12 Assessment of Bone Mass, Structure, and Quality in Rodents 93
Jeffry S. Nyman and Deepak Vashishth 13 Skeletal Healing Cellular and Molecular Determinants 101
Alayna E. Loiselle and Michael J. Zuscik 14 Biomechanics of Fracture Healing 108
Elise F. Morgan, Amira I. Hussein, and Thomas A. Einhorn Section II Skeletal Physiology 115Section Editor Ego Seeman 15 Human Fetal and Neonatal Bone Development 117
Tao Yang, Monica Grover, Kyu Sang Joeng, and Brendan Lee 16 Skeletal Growth a Major Determinant of Bone's Structural Diversity in Women and Men 123
Ego Seeman 17 Racial Differences in the Acquisition and Age¿related Loss of Bone Strength 131
Shane A. Norris, Marcella D. Walker, Kate Ward, Lisa K. Micklesfield, and John M. Pettifor 18 Calcium, Vitamin D, and Other Nutrients During Growth 135
Tania Winzenberg and Graeme Jones 19 Mechanical Loading and the Developing Skeleton 141
Mark R. Forwood 20 Pregnancy and Lactation 147
Christopher S. Kovacs and Henry M. Kronenberg 21 Menopause and Age¿related Bone Loss 155
Carlos M. Isales and Ego Seeman Section III Mineral Homeostasis 163Section Editors David Goltzman and Harald Jüppner 22 Regulation of Calcium Homeostasis 165
Line Vautour and David Goltzman 23 Magnesium Homeostasis 173
Aliya Aziz Khan, Asiya Sbayi, and Karl Peter Schlingmann 24 Fetal Calcium Metabolism 179
Christopher S. Kovacs 25 FGF23 and the Regulation of Phosphorus Metabolism 187
Kenneth E. White and Michael J. Econs 26 Gonadal Steroids 194
Stavros C. Manolagas and Maria Schuller Almeida 27 Parathyroid Hormone 205
Thomas J. Gardella, Robert A. Nissenson, and Harald Jüppner 28 Parathyroid Hormone¿Related Protein 212
John J. Wysolmerski and T. John Martin 29 Calcium¿Sensing Receptor 221
Geoffrey N. Hendy 30 Vitamin D Production, Metabolism, Action, and Clinical Requirements 230
Daniel D. Bikle, John S. Adams, and Sylvia Christakos Section IV Investigation of Metabolic Bone Diseases 241Section Editors Douglas C. Bauer and Klaus Engelke 31 Techniques of Bone Mass Measurement in Children with Risk Factors for Osteoporosis 243
Nicola J. Crabtree and Leanne M. Ward 32 Standard Techniques of Bone Mass Measurement in Adults 252
E. Michael Lewiecki, Paul D. Miller, and Nelson B. Watts 33 Advanced Techniques of Bone Mass Measurements and Strength in Adults 260
Kyle K. Nishiyama, Enrico Dall'Ara, and Klaus Engelke 34 Magnetic Resonance Imaging of Bone 272
Sharmila Majumdar 35 Trabecular Bone Score 277
Barbara C. Silva and William D. Leslie 36 Reference Point Indentation 287
Adolfo Diez¿Perez and Joshua N. Farr 37 Biochemical Markers of Bone Turnover in Osteoporosis 293
Pawel Szulc, Douglas C. Bauer, and Richard Eastell 38 Scintigraphy and PET in Metabolic Bone Disease 302
Lorenzo Nardo, Paola A. Erba, and Benjamin L. Franc 39 Bone Histomorphometry in Clinical Practice 310
Robert R. Recker and Carolina Aguiar Moreira 40 Diagnosis and Classification of Vertebral Fracture 319
James F. Griffith and Harry K. Genant 41 FRAX Assessment of Fracture Risk 331
John A. Kanis, Eugene V. McCloskey, Nicholas C. Harvey, and William D. Leslie Section V Genetics of Bone 341Section Editor Rajesh V. Thakker 42 Introduction to Genetics 343
Paul J. Newey, Michael P. Whyte, and Rajesh V. Thakker 43 Animal Models Genetic Manipulation 351
Karen Lyons 44 Animal Models Allelic Determinants for Bone Mineral Density 359
J. H. Duncan Bassett, Graham R. Williams, and Robert D. Blank 45 Transcriptional Profiling for Genetic Assessment 367
Aimy Sebastian and Gabriela G. Loots 46 Approaches to Genetic Testing 373
Christina Jacobsen, Yiping Shen, and Ingrid A. Holm 47 Human Genome¿Wide Association Studies 378
Douglas P. Kiel, Emma L. Duncan, and Fernando Rivadeneira 48 Translational Genetics of Osteoporosis From Population Association to Individualized Assessment 385
Bich Tran, Jacqueline R. Center, and Tuan V. Nguyen Section VI Osteoporosis 393Section Editors Paul D. Miller, Socrates E. Papapoulos, and Michael R. McClung 49 Osteoporosis an Overview 395
Michael R. McClung, Paul D. Miller, and Socrates E. Papapoulos 50 The Epidemiology of Osteoporotic Fractures 398
Nicholas C. Harvey, Elizabeth M. Curtis, Elaine M. Dennison, and Cyrus Cooper 51 Fracture Liaison Service 405
Piet Geusens, John A. Eisman, Andrea Singer, and Joop van den Bergh 52 Sex Steroids and the Pathogenesis of Osteoporosis 412
Matthew T. Drake and Sundeep Khosla 53 Juvenile Osteoporosis 419
Francis H. Glorieux and Craig Munns 54 Transplantation Osteoporosis 424
Peter R. Ebeling 55 Premenopausal Osteoporosis 436
Adi Cohen and Elizabeth Shane 56 Osteoporosis in Men 443
Eric S. Orwoll and Robert A. Adler 57 Bone Stress Injuries 450
Stuart J. Warden and David B. Burr 58 Inflammation¿Induced Bone Loss in the Rheumatic Diseases 459
Ellen M. Gravallese and Steven R. Goldring 59 Glucocorticoid¿Induced Osteoporosis 467
Kenneth Saag and Robert A. Adler 60 Human Immunodeficiency Virus and Bone 474
Michael T. Yin and Todd T. Brown 61 Effects on the Skeleton from Medications Used to Treat Nonskeletal Disorders 482
Nelson B. Watts 62 Diabetes and Fracture Risk 487
Serge Ferrari, Nicola Napoli, and Ann Schwartz 63 Obesity and Skeletal Health 492
Juliet Compston 64 Sarcopenia and Osteoporosis 498
Gustavo Duque and Neil Binkley 65 Management of Osteoporosis in Patients with Chronic Kidney Disease 505
Paul D. Miller 66 Other Secondary Causes of Osteoporosis 510
Neveen A. T. Hamdy and Natasha M. Appelman¿Dijkstra 67 Exercise for Osteoporotic Fracture Prevention and Management 517
Robin M. Daly and Lora Giangregorio 68 Prevention of Falls 526
Heike A. Bischoff¿Ferrari 69 Nutritional Support for Osteoporosis 534
Connie M. Weaver, Bess Dawson¿Hughes, Rene Rizzoli, and Robert P. Heaney 70 Estrogens, Selective Estrogen Receptor Modulators, and Tissue¿Selective Estrogen Complex 541
Tobias J. de Villiers 71 Bisphosphonates for Postmenopausal Osteoporosis 545
Andrea Giusti and Socrates E. Papapoulos 72 Denosumab 553
Aline Granja Costa, E. Michael Lewiecki, and John P. Bilezikian 73 Parathyroid Hormone and Abaloparatide Treatment for Osteoporosis 559
Felicia Cosman and Susan L. Greenspan 74 Combination Anabolic and Antiresorptive Therapy for Osteoporosis 567
Joy N. Tsai and Benjamin Z. Leder 75 Strontium Ranelate and Calcitonin 573
Leonardo Bandeira and E. Michael Lewiecki 76 Adverse Effects of Drugs for Osteoporosis 579
Bo Abrahamsen and Daniel PrietöAlhambra 77 Orthopedic Principles of Fracture Management 588
Manoj Ramachandran and David G. Little 78 Adherence to Osteoporosis Therapies 593
Stuart L. Silverman and Deborah T. Gold 79 Cost¿Effectiveness of Osteoporosis Treatment 597
Anna N.A. Tosteson 80 Future Therapies 603
Michael R. McClung Section VII Metabolic Bone Diseases 611Section Editors Suzanne M. Jan de Beur and Peter R. Ebeling 81 Approach to Parathyroid Disorders 613
John P. Bilezikian 82 Primary Hyperparathyroidism 619
Shonni J. Silverberg, Francisco Bandeira, Jianmin Liu, Claudio Marcocci, and Marcella D. Walker 83 Familial States of Primary Hyperparathyroidism 629
Andrew Arnold, Sunita K. Agarwal, and Rajesh V. Thakker 84 Non¿Parathyroid Hypercalcemia 639
Mara J. Horwitz 85 Hypocalcemia Definition, Etiology, Pathogenesis, Diagnosis, and Management 646
Anne L. Schafer and Dolores M. Shoback 86 Hypoparathyroidism 654
Tamara Vokes, Mishaela R. Rubin, Karen K. Winer, Michael Mannstadt, Natalie E. Cusano, Harald Jüppner, and John P. Bilezikian 87 Pseudohypoparathyroidism 661
Agnès Linglart, Michael A. Levine, and Harald Jüppner 88 Disorders of Phosphate Homeostasis 674
Mary D. Ruppe and Suzanne M. Jan de Beur 89 Rickets and Osteomalacia 684
Michaël R. Laurent, Nathalie Bravenboer, Natasja M. Van Schoor, Roger Bouillon, John M. Pettifor, and Paul Lips 90 Pathophysiology and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder 695
Mark R. Hanudel, Sharon M. Moe, and Isidro B. Salusky 91 Disorders of Mineral Metabolism in Childhood 705
Thomas O. Carpenter and Nina S. Ma 92 Paget Disease of Bone 713
Julia F. Charles, Ethel S. Siris, and G. David Roodman 93 Epidemiology, Diagnosis, Evaluation, and Treatment of Nephrolithiasis 721
Murray J. Favus and David A. Bushinsky 94 Immobilization and Burns Other Conditions Associated with Osteoporosis 730
William A. Bauman, Christopher Cardozo, and Gordon L. Klein Section VIII Cancer and Bone 737Section Editors Theresa Guise and G. David...
John P. Bilezikian xxiv About ASBMR xxv President's Preface Michael J. Econs xxvi About the Companion Website xxvii Section I Molecular and Cellular Determinants of Bone Structure and Function 1Section Editor Karen Lyons 1 Early Skeletal Morphogenesis in Embryonic Development 3
Yingzi Yang 2 Endochondral Ossification 12
Courtney M. Karner and Matthew J. Hilton 3 Local and Circulating Osteoprogenitor Cells and Lineages 20
Naomi Dirckx and Christa Maes 4 Osteoblasts Function, Development, and Regulation 31
Elizabeth W. Bradley, Jennifer J. Westendorf, Andre J. van Wijnen, and Amel Dudakovic 5 Osteocytes 38
Lynda F. Bonewald 6 Osteoclast Biology and Bone Resorption 46
Hiroshi Takayanagi 7 Signal Transduction Cascades Controlling Osteoblast Differentiation 54
David J.J. de Gorter, Gonzalo Sánchez¿Duffhues, and Peter ten Dijke 8 The TGF¿ß Superfamily in Bone Formation and Maintenance 60
Ce Shi and Yuji Mishina 9 Recent Developments in Understanding the Role of Wnt Signaling in Skeletal Development and Disease 68
Zhendong A. Zhong, Nicole J. Ethen, and Bart O. Williams 10 Mechanotransduction in Bone Formation and Maintenance 75
Whitney A. Bullock, Lilian I. Plotkin, Alexander G. Robling, and Fredrick M. Pavalko 11 The Composition of Bone 84
Adele L. Boskey and Pamela G. Robey 12 Assessment of Bone Mass, Structure, and Quality in Rodents 93
Jeffry S. Nyman and Deepak Vashishth 13 Skeletal Healing Cellular and Molecular Determinants 101
Alayna E. Loiselle and Michael J. Zuscik 14 Biomechanics of Fracture Healing 108
Elise F. Morgan, Amira I. Hussein, and Thomas A. Einhorn Section II Skeletal Physiology 115Section Editor Ego Seeman 15 Human Fetal and Neonatal Bone Development 117
Tao Yang, Monica Grover, Kyu Sang Joeng, and Brendan Lee 16 Skeletal Growth a Major Determinant of Bone's Structural Diversity in Women and Men 123
Ego Seeman 17 Racial Differences in the Acquisition and Age¿related Loss of Bone Strength 131
Shane A. Norris, Marcella D. Walker, Kate Ward, Lisa K. Micklesfield, and John M. Pettifor 18 Calcium, Vitamin D, and Other Nutrients During Growth 135
Tania Winzenberg and Graeme Jones 19 Mechanical Loading and the Developing Skeleton 141
Mark R. Forwood 20 Pregnancy and Lactation 147
Christopher S. Kovacs and Henry M. Kronenberg 21 Menopause and Age¿related Bone Loss 155
Carlos M. Isales and Ego Seeman Section III Mineral Homeostasis 163Section Editors David Goltzman and Harald Jüppner 22 Regulation of Calcium Homeostasis 165
Line Vautour and David Goltzman 23 Magnesium Homeostasis 173
Aliya Aziz Khan, Asiya Sbayi, and Karl Peter Schlingmann 24 Fetal Calcium Metabolism 179
Christopher S. Kovacs 25 FGF23 and the Regulation of Phosphorus Metabolism 187
Kenneth E. White and Michael J. Econs 26 Gonadal Steroids 194
Stavros C. Manolagas and Maria Schuller Almeida 27 Parathyroid Hormone 205
Thomas J. Gardella, Robert A. Nissenson, and Harald Jüppner 28 Parathyroid Hormone¿Related Protein 212
John J. Wysolmerski and T. John Martin 29 Calcium¿Sensing Receptor 221
Geoffrey N. Hendy 30 Vitamin D Production, Metabolism, Action, and Clinical Requirements 230
Daniel D. Bikle, John S. Adams, and Sylvia Christakos Section IV Investigation of Metabolic Bone Diseases 241Section Editors Douglas C. Bauer and Klaus Engelke 31 Techniques of Bone Mass Measurement in Children with Risk Factors for Osteoporosis 243
Nicola J. Crabtree and Leanne M. Ward 32 Standard Techniques of Bone Mass Measurement in Adults 252
E. Michael Lewiecki, Paul D. Miller, and Nelson B. Watts 33 Advanced Techniques of Bone Mass Measurements and Strength in Adults 260
Kyle K. Nishiyama, Enrico Dall'Ara, and Klaus Engelke 34 Magnetic Resonance Imaging of Bone 272
Sharmila Majumdar 35 Trabecular Bone Score 277
Barbara C. Silva and William D. Leslie 36 Reference Point Indentation 287
Adolfo Diez¿Perez and Joshua N. Farr 37 Biochemical Markers of Bone Turnover in Osteoporosis 293
Pawel Szulc, Douglas C. Bauer, and Richard Eastell 38 Scintigraphy and PET in Metabolic Bone Disease 302
Lorenzo Nardo, Paola A. Erba, and Benjamin L. Franc 39 Bone Histomorphometry in Clinical Practice 310
Robert R. Recker and Carolina Aguiar Moreira 40 Diagnosis and Classification of Vertebral Fracture 319
James F. Griffith and Harry K. Genant 41 FRAX Assessment of Fracture Risk 331
John A. Kanis, Eugene V. McCloskey, Nicholas C. Harvey, and William D. Leslie Section V Genetics of Bone 341Section Editor Rajesh V. Thakker 42 Introduction to Genetics 343
Paul J. Newey, Michael P. Whyte, and Rajesh V. Thakker 43 Animal Models Genetic Manipulation 351
Karen Lyons 44 Animal Models Allelic Determinants for Bone Mineral Density 359
J. H. Duncan Bassett, Graham R. Williams, and Robert D. Blank 45 Transcriptional Profiling for Genetic Assessment 367
Aimy Sebastian and Gabriela G. Loots 46 Approaches to Genetic Testing 373
Christina Jacobsen, Yiping Shen, and Ingrid A. Holm 47 Human Genome¿Wide Association Studies 378
Douglas P. Kiel, Emma L. Duncan, and Fernando Rivadeneira 48 Translational Genetics of Osteoporosis From Population Association to Individualized Assessment 385
Bich Tran, Jacqueline R. Center, and Tuan V. Nguyen Section VI Osteoporosis 393Section Editors Paul D. Miller, Socrates E. Papapoulos, and Michael R. McClung 49 Osteoporosis an Overview 395
Michael R. McClung, Paul D. Miller, and Socrates E. Papapoulos 50 The Epidemiology of Osteoporotic Fractures 398
Nicholas C. Harvey, Elizabeth M. Curtis, Elaine M. Dennison, and Cyrus Cooper 51 Fracture Liaison Service 405
Piet Geusens, John A. Eisman, Andrea Singer, and Joop van den Bergh 52 Sex Steroids and the Pathogenesis of Osteoporosis 412
Matthew T. Drake and Sundeep Khosla 53 Juvenile Osteoporosis 419
Francis H. Glorieux and Craig Munns 54 Transplantation Osteoporosis 424
Peter R. Ebeling 55 Premenopausal Osteoporosis 436
Adi Cohen and Elizabeth Shane 56 Osteoporosis in Men 443
Eric S. Orwoll and Robert A. Adler 57 Bone Stress Injuries 450
Stuart J. Warden and David B. Burr 58 Inflammation¿Induced Bone Loss in the Rheumatic Diseases 459
Ellen M. Gravallese and Steven R. Goldring 59 Glucocorticoid¿Induced Osteoporosis 467
Kenneth Saag and Robert A. Adler 60 Human Immunodeficiency Virus and Bone 474
Michael T. Yin and Todd T. Brown 61 Effects on the Skeleton from Medications Used to Treat Nonskeletal Disorders 482
Nelson B. Watts 62 Diabetes and Fracture Risk 487
Serge Ferrari, Nicola Napoli, and Ann Schwartz 63 Obesity and Skeletal Health 492
Juliet Compston 64 Sarcopenia and Osteoporosis 498
Gustavo Duque and Neil Binkley 65 Management of Osteoporosis in Patients with Chronic Kidney Disease 505
Paul D. Miller 66 Other Secondary Causes of Osteoporosis 510
Neveen A. T. Hamdy and Natasha M. Appelman¿Dijkstra 67 Exercise for Osteoporotic Fracture Prevention and Management 517
Robin M. Daly and Lora Giangregorio 68 Prevention of Falls 526
Heike A. Bischoff¿Ferrari 69 Nutritional Support for Osteoporosis 534
Connie M. Weaver, Bess Dawson¿Hughes, Rene Rizzoli, and Robert P. Heaney 70 Estrogens, Selective Estrogen Receptor Modulators, and Tissue¿Selective Estrogen Complex 541
Tobias J. de Villiers 71 Bisphosphonates for Postmenopausal Osteoporosis 545
Andrea Giusti and Socrates E. Papapoulos 72 Denosumab 553
Aline Granja Costa, E. Michael Lewiecki, and John P. Bilezikian 73 Parathyroid Hormone and Abaloparatide Treatment for Osteoporosis 559
Felicia Cosman and Susan L. Greenspan 74 Combination Anabolic and Antiresorptive Therapy for Osteoporosis 567
Joy N. Tsai and Benjamin Z. Leder 75 Strontium Ranelate and Calcitonin 573
Leonardo Bandeira and E. Michael Lewiecki 76 Adverse Effects of Drugs for Osteoporosis 579
Bo Abrahamsen and Daniel PrietöAlhambra 77 Orthopedic Principles of Fracture Management 588
Manoj Ramachandran and David G. Little 78 Adherence to Osteoporosis Therapies 593
Stuart L. Silverman and Deborah T. Gold 79 Cost¿Effectiveness of Osteoporosis Treatment 597
Anna N.A. Tosteson 80 Future Therapies 603
Michael R. McClung Section VII Metabolic Bone Diseases 611Section Editors Suzanne M. Jan de Beur and Peter R. Ebeling 81 Approach to Parathyroid Disorders 613
John P. Bilezikian 82 Primary Hyperparathyroidism 619
Shonni J. Silverberg, Francisco Bandeira, Jianmin Liu, Claudio Marcocci, and Marcella D. Walker 83 Familial States of Primary Hyperparathyroidism 629
Andrew Arnold, Sunita K. Agarwal, and Rajesh V. Thakker 84 Non¿Parathyroid Hypercalcemia 639
Mara J. Horwitz 85 Hypocalcemia Definition, Etiology, Pathogenesis, Diagnosis, and Management 646
Anne L. Schafer and Dolores M. Shoback 86 Hypoparathyroidism 654
Tamara Vokes, Mishaela R. Rubin, Karen K. Winer, Michael Mannstadt, Natalie E. Cusano, Harald Jüppner, and John P. Bilezikian 87 Pseudohypoparathyroidism 661
Agnès Linglart, Michael A. Levine, and Harald Jüppner 88 Disorders of Phosphate Homeostasis 674
Mary D. Ruppe and Suzanne M. Jan de Beur 89 Rickets and Osteomalacia 684
Michaël R. Laurent, Nathalie Bravenboer, Natasja M. Van Schoor, Roger Bouillon, John M. Pettifor, and Paul Lips 90 Pathophysiology and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder 695
Mark R. Hanudel, Sharon M. Moe, and Isidro B. Salusky 91 Disorders of Mineral Metabolism in Childhood 705
Thomas O. Carpenter and Nina S. Ma 92 Paget Disease of Bone 713
Julia F. Charles, Ethel S. Siris, and G. David Roodman 93 Epidemiology, Diagnosis, Evaluation, and Treatment of Nephrolithiasis 721
Murray J. Favus and David A. Bushinsky 94 Immobilization and Burns Other Conditions Associated with Osteoporosis 730
William A. Bauman, Christopher Cardozo, and Gordon L. Klein Section VIII Cancer and Bone 737Section Editors Theresa Guise and G. David...
Details
| Erscheinungsjahr: | 2018 |
|---|---|
| Fachbereich: | Allgemeines |
| Genre: | Biologie |
| Rubrik: | Naturwissenschaften & Technik |
| Thema: | Lexika |
| Medium: | Taschenbuch |
| Inhalt: | 1136 S. |
| ISBN-13: | 9781119266563 |
| ISBN-10: | 1119266564 |
| Sprache: | Englisch |
| Einband: | Kartoniert / Broschiert |
| Redaktion: | Bilezikian, John P. |
| Herausgeber: | John P Bilezikian |
| Auflage: | 9th edition |
| Hersteller: | Wiley |
| Maße: | 280 x 221 x 47 mm |
| Von/Mit: | John P. Bilezikian |
| Erscheinungsdatum: | 06.12.2018 |
| Gewicht: | 2,795 kg |
Warnhinweis
Ähnliche Produkte
Buch
Aktuell nicht verfügbar
Taschenbuch
Lieferzeit 1-2 Wochen
Taschenbuch
Lieferzeit 4-7 Werktage
Taschenbuch
Aktuell nicht verfügbar
Buch
Aktuell nicht verfügbar
Taschenbuch
Lieferzeit 1-2 Wochen
Taschenbuch
Lieferzeit 1-2 Wochen
Taschenbuch
Lieferzeit 1-2 Wochen