Eduardo Anitua, MD, DDS, PhD is Director of the Instituto Eduardo Anitua, Vitoria, Spain. He has lectured at more than 500 courses and conferences on implants, prosthesis, dental aesthetics and tissue regeneration in Spain and abroad in Europe, United States, South America and Asia. In addition to lecturing, he has authored and co-authored more than 10 books and book chapters and more than 100 research and review articles in National and International journals including TRENDS, PPAD, JOMI, JOI, Clinic, Oral Implant Research, Thrombosis and Haemostasis.

Mikel Sanchez, MD is scientific director and medical Unit Arthroscopic Surgery (UCA) of Vithas Hospital San José, Vitoria-Gasteiz. In addition to the UCA, he was the founder of the first unit Biological Therapy (UTB) in Vitoria-Gasteiz. His scientific merits include his pioneering work in the advancement of arthroscopic surgery in Spain and Europe, and being the first physician to understand the therapeutic potential of growth factors in the different diseases of the locomotor system, along with developing protocols for its application in traumatology.

Part 1. Basic science.- Platelets: at the interface between inflammation and repair process.- Characterization of plasma rich in growth factor: content and formulation.- Effects of PRGF on cells and tissues of musculoskeletal system: from muscle to articular cartilage.- Regeneration: connecting the dots among hemostasis and clotting, immune system, and fibrogenesis.- PRGF molecular intervention to enhance muscle perfusion and tissue remodeling.- Part 2. Oral and Maxillofacial surgery.- The use of plasma rich in growth factor in the treatment of post-extraction defects.- Efficacy and safety of PRGF versus platelet rich fibrin in post-extraction defects.- An autologous treatment to a challenging pathology medication-related osteonecrosis of the jaw. Part 3. Orthopaedics & Sports Medicine.- A biological approach to apply plasma rich in growth factors on joint tissues.- Scientific evidence of the effects of PRGF on musculoskeletal tissues in animal model.- A new approach to treat jointand cartilage injuries: intraosseous infiltrations of PRGF.- Knee Osteoarthritis: one versus two cycles of PRGF infiltrations treatment.- Application of PRGF on Sports-related injuries.- Why to use Plasma rich in growth factors on the repair of damaged tendons.- Infiltrations of PRGF to treat ligament injuries.- Treatment of injured peripheral nerves with PRGF: from bench to patient.- Treatment of tendinopathies with Plasma rich in growth factors.- Intradiscal and intra-articular facet infiltrations with plasma rich in growth factors to treat chronic low back pain.