Pharmaceutical Powder and Particles | Buch

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Cover: 9783319912196 | Pharmaceutical Powder and Particles | Stefano Giovagnoli (u. a.) | IX

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Sprache: Englisch

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Beschreibung

This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an essential primer for any scientists involved in powder or particle research and manufacturing. It is appropriate for those just entering the field or as a rapid reference for the experienced pharmaceutical scientist. The authors have both academic and industrial experience and the coverage includes solid state chemistry; crystallization; physical processes; particle size and distribution;particle interaction;manufacturing processes;quality by design;and a general discussion of the industry. Pharmaceutical Powder and Particles is intended to concisely review important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance.

Über den Autor

Anthony Hickey, Ph.D., is a Distinguished RTI Fellow (appointed June 2012), and a senior research pharmacologist at RTI International. Dr. Hickey has more than 30 years of academic and research experience in pulmonary biology, aerosol physics, powder dynamics, pharmacokinetics and drug disposition, formulation design, and device development. Since joining RTI in 2011, he has conducted research related to pulmonary drug and vaccine delivery for tuberculosis treatment and prevention and directed a program in nanotechnology informatics. Additionally, Dr. Hickey is an adjunct professor of biomedical engineering at the University of North Carolina at Chapel Hill School of Medicine, emeritus professor of molecular pharmaceutics at the University of North Carolina at Chapel Hill, Eshelman School of Pharmacy, and founder of Cirrus Pharmaceuticals, Inc., Oriel Therapeutics, Inc. and Astartein LLC. He has received many awards and honors and is an active member of several professional societies and committees, including the American Association for Aerosol Research, American Chemical Society, International Association of Colloid and Interface Scientists, International Society for Aerosols in Medicine, and the Society of Toxicology. He is a fellow of the American Association of Pharmaceutical Scientists, the American Association for the Advancement of Science, the Royal Society of Biology and Royal Society of Medicine. Dr. Hickey holds 25 patents and has authored numerous books, book chapters, and more than 200 journal articles.

Stefano Giovagnoli graduated in chemistry in 1997 at the University of Perugia. After being R&D researcher at the GlaxoSmithKlein, Ware, England, he completed his Ph.D. studies on micro- and nanoparticulate systems for the delivery of antioxidants and proteins at the University of Perugia, spending part of his doctoral work at the University of Kentucky,Lexington, Kentucky, in the laboratories of Professor Patrick P. DeLuca. In 2004, this work was chosen as a recipient of the 2004 AAPS Outstanding Graduate Student Research Award in Pharmaceutical Technologies by Solvay Pharmaceuticals and the American Association of Pharmaceutical Scientists (AAPS). As a postdoc he worked at the School of Pharmacy, University of Kentucky, Lexington, Kentucky and as a researcher at the Department of Chemistry and Technology of drugs, University of Perugia, Italy. He is currently Associate Professor of Pharmaceutical technology and Biotechnology at the Department of Pharmaceutical Sciences, University of Perugia. His research focuses primarily on the formulation and characterization of respirable powders for the treatment of pulmonary infections, organic and inorganic nanoparticles for targeted and local delivery and the engineering of cells as drug delivery systems and therapeutic tools. It serves as a referee for several international scientific journals and as a Board Editor of the Journal of Pharmaceutical Innovation, Review Editor of Frontiers in Pharmacology, Board of the Journal of Medicinal Chemistry and Research. He is member of the American Association of Pharmaceutical Scientists (AAPS), Italian Chemical Society (SCI), AAPS Italian University Network (AItUN), the Association of Italian Faculties of Pharmaceutical Technology and Regulation (ADRITELF) and the Italian CRS chapter. He has about 100 presentations at international congresses and conferences, more than 72 publications, 2 book chapters and 3 patents.

Zusammenfassung

Concisely reviews important aspects of powder and particle systems

Essential primer or rapid reference guide for the new scentist or experienced professional

Emphasizes quality by design

Inhaltsverzeichnis

Introduction.- Importance of Finely Divided Solids in Pharmaceutical Dosage Forms.- Solid State Chemistry.- Crystallization.- Physical Properties.- Particle Size and Size Distribution.- Particle Size Characterization.- Fundamental of Particle Interactions.- Powder and Particle Dependent Traditional Manufacturing Processes (unit operations).- Powder and Particle Dependent Biopharmaceutical Processes.- Recent and Evolving Manufacturing Processes.- Principles of Quality by Design.- General Discussion.

Details

Erscheinungsjahr:	2018
Fachbereich:	Toxikologie
Genre:	Medizin
Rubrik:	Wissenschaften
Medium:	Buch
Seiten:	116
Reihe:	AAPS Introductions in the Pharmaceutical Sciences
Inhalt:	ix 104 S. 22 s/w Illustr. 13 farbige Illustr. 104 p. 35 illus. 13 illus. in color.
ISBN-13:	9783319912196
ISBN-10:	3319912194
Sprache:	Englisch
Herstellernummer:	978-3-319-91219-6
Ausstattung / Beilage:	HC runder Rücken kaschiert
Einband:	Gebunden
Autor:	Giovagnoli, Stefano Hickey, Anthony J.
Auflage:	1st ed. 2018
Hersteller:	Springer International Publishing Springer International Publishing AG AAPS Introductions in the Pharmaceutical Sciences
Maße:	241 x 160 x 13 mm
Von/Mit:	Stefano Giovagnoli (u. a.)
Erscheinungsdatum:	23.08.2018
Gewicht:	0,348 kg

preigu-id: 113403574