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Personalized Medicine for Parkinson's Disease
New Concepts and Future of Individualized Management
Sprache: Englisch

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Beschreibung
Personalized medicine for Parkinson's disease is a growing and emerging concept in light of recent recognition that Parkinson's is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven "one size fits all" management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital "checklists" to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
Personalized medicine for Parkinson's disease is a growing and emerging concept in light of recent recognition that Parkinson's is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven "one size fits all" management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital "checklists" to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
Details
Erscheinungsjahr: 2023
Fachbereich: Allgemeine Lexika
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Seiten: 214
ISBN-13: 9783036562124
ISBN-10: 3036562125
Sprache: Englisch
Ausstattung / Beilage: HC gerader Rücken kaschiert
Einband: Gebunden
Hersteller: MDPI AG
Maße: 250 x 175 x 18 mm
Erscheinungsdatum: 09.01.2023
Gewicht: 0,737 kg
preigu-id: 126448315
Details
Erscheinungsjahr: 2023
Fachbereich: Allgemeine Lexika
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Seiten: 214
ISBN-13: 9783036562124
ISBN-10: 3036562125
Sprache: Englisch
Ausstattung / Beilage: HC gerader Rücken kaschiert
Einband: Gebunden
Hersteller: MDPI AG
Maße: 250 x 175 x 18 mm
Erscheinungsdatum: 09.01.2023
Gewicht: 0,737 kg
preigu-id: 126448315
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