Foreword by Professor Peter Slinger, vi Preface, vii

Part 1: Basic Principles

1. Functional Anatomy of the Respiratory Tract, 2
2. Elastic Forces and Lung Volumes, 14
3. Respiratory System Resistance, 27
4. Control of Breathing, 42
5. Pulmonary Ventilation, 59
6. The Pulmonary Circulation, 73
7. Distribution of Pulmonary Ventilation and Perfusion, 88
8. Diffusion of Respiratory Gases, 111
9. Carbon Dioxide, 122
10. Oxygen, 136
11. Nonrespiratory Functions of the Lung, 164

Part 2: Applied Physiology

12. Pregnancy, Neonates and Children, 175
13. Exercise, 183
14. Sleep, 191
15. Obesity, 199
16. High Altitude and Flying, 205
17. High Pressure and Diving, 218
18. Respiration in Closed Environments and Space, 225
19. Drowning, 233
20. Smoking and Air Pollution, 236
21. Anaesthesia, 244
22. Changes in the Carbon Dioxide Partial Pressure, 268
23. Hypoxia, 273
24. Anaemia, 279
25. Oxygen Toxicity and Hyperoxia, 285
26. Comparative Respiratory Physiology, 299

Part 3: Physiology of Pulmonary Disease

27. Ventilatory Failure, 316
28. Airways Disease, 324
29. Pulmonary Vascular Disease, 339
30. Diseases of the Lung Parenchyma and Pleura, 349
31. Acute Lung Injury, 365
32. Respiratory Support and Artificial Ventilation, 375
33. Pulmonary Surgery, 398

Appendix A Physical Quantities and Units of Measurement, 412
Appendix B The Gas Laws, 415
Appendix C Conversion Factors for Gas Volumes, 417
Appendix D Symbols and Abbreviations, 418
Appendix E Mathematical Functions Relevant to Respiratory Physiology, 419

Online Content

34. The Atmosphere
35. The History of Respiratory Physiology

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Index, 42