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Cover: 9783662496497 | Molecular Radio-Oncology | Michael Baumann (u. a.) | Buch | ix | 2016
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Molecular Radio-Oncology
Buch von Michael Baumann (u. a.)
Sprache: Englisch

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Beschreibung
This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography.By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.
This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography.By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.
Über den Autor
Michael Baumann, University of Technology, Dresden, Germany.
Mechthild Krause, University of Technology, Dresden, Germany.
Nils Cordes, University of Technology, Dresden, Germany.
Zusammenfassung

Reviews our current understanding of the most important aspects of molecular radiobiology

Discusses recent efforts to identify reasonable and clinically applicable biomarkers

Describes how molecular information is being exploited for diagnostic imaging and imaging throughout treatment

Includes supplementary material: [...]

Inhaltsverzeichnis
Molecular Radiobiology: Hypoxia.- Molecular Targeting of Growth Factor Receptor Signaling.- Molecular Targeting of Cell Adhesion Molecules.- Tumor Pathophysiology.- DNA Repair.- Cancer Stem Cells.- Normal Tissue. Biomarkers/Personalized Radiation Oncology: EGFR and other RTKs.- HPV.- Hypoxia.- Study design for Biomarker research in radiation oncology.- Gene expression/system biology. Molecular Imaging in Radiation Oncology:FMISO as a biomarker for clinical radiation oncology.- FDG and beyond.- Molecular imaging techniques beyond PET.
Details
Erscheinungsjahr: 2016
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Reihe: Recent Results in Cancer Research
Inhalt: ix
201 S.
6 s/w Illustr.
24 farbige Illustr.
201 p. 30 illus.
24 illus. in color.
ISBN-13: 9783662496497
ISBN-10: 3662496496
Sprache: Englisch
Herstellernummer: 978-3-662-49649-7
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Baumann, Michael
Cordes, Nils
Krause, Mechthild
Herausgeber: Michael Baumann/Mechthild Krause/Nils Cordes
Auflage: 1st ed. 2016
Hersteller: Springer-Verlag GmbH
Springer Berlin Heidelberg
Recent Results in Cancer Research
Maße: 241 x 160 x 18 mm
Von/Mit: Michael Baumann (u. a.)
Erscheinungsdatum: 23.06.2016
Gewicht: 0,489 kg
Artikel-ID: 103980966
Über den Autor
Michael Baumann, University of Technology, Dresden, Germany.
Mechthild Krause, University of Technology, Dresden, Germany.
Nils Cordes, University of Technology, Dresden, Germany.
Zusammenfassung

Reviews our current understanding of the most important aspects of molecular radiobiology

Discusses recent efforts to identify reasonable and clinically applicable biomarkers

Describes how molecular information is being exploited for diagnostic imaging and imaging throughout treatment

Includes supplementary material: [...]

Inhaltsverzeichnis
Molecular Radiobiology: Hypoxia.- Molecular Targeting of Growth Factor Receptor Signaling.- Molecular Targeting of Cell Adhesion Molecules.- Tumor Pathophysiology.- DNA Repair.- Cancer Stem Cells.- Normal Tissue. Biomarkers/Personalized Radiation Oncology: EGFR and other RTKs.- HPV.- Hypoxia.- Study design for Biomarker research in radiation oncology.- Gene expression/system biology. Molecular Imaging in Radiation Oncology:FMISO as a biomarker for clinical radiation oncology.- FDG and beyond.- Molecular imaging techniques beyond PET.
Details
Erscheinungsjahr: 2016
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Reihe: Recent Results in Cancer Research
Inhalt: ix
201 S.
6 s/w Illustr.
24 farbige Illustr.
201 p. 30 illus.
24 illus. in color.
ISBN-13: 9783662496497
ISBN-10: 3662496496
Sprache: Englisch
Herstellernummer: 978-3-662-49649-7
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Baumann, Michael
Cordes, Nils
Krause, Mechthild
Herausgeber: Michael Baumann/Mechthild Krause/Nils Cordes
Auflage: 1st ed. 2016
Hersteller: Springer-Verlag GmbH
Springer Berlin Heidelberg
Recent Results in Cancer Research
Maße: 241 x 160 x 18 mm
Von/Mit: Michael Baumann (u. a.)
Erscheinungsdatum: 23.06.2016
Gewicht: 0,489 kg
Artikel-ID: 103980966
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