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Cover: 9783319127651 | Molecular Mechanisms Underpinning the Development of Obesity | Buch
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Molecular Mechanisms Underpinning the Development of Obesity
Buch von Raquel Rodriguez-López (u. a.)
Sprache: Englisch

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Beschreibung
Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.
Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.
Zusammenfassung

Offers a comprehensive review of efforts aimed at uncovering genetic variants associated with obesity

Reviews genome-wide association studies, along with studies on monogenic and polygenic obesity

Identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health, including nutrigenomics

Includes supplementary material: [...]

Inhaltsverzeichnis
Challenges in understanding development of obesity.- Monogenic forms of obesity.- Heterogeneous obesity syndromes: new strategies for diagnosis.- Genetic contribution: common forms of obesity.- The role of the GWAS identified FTO locus in regulating body size and composition.- Neural vulnerability factors that increase risk for weight gain: prevention and treatment implications.- Molecular mechanisms involved in the regulation of food intake.- Epigenetics of human obesity: a link between genetics and nutrition.- MicroRNAs in obesity and metabolism.- Obesity study: animal models.- From Homo obesus to Homo diabesus: neuroadipology insight.- Obesity and type 2 diabetes. ¿
Details
Erscheinungsjahr: 2014
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Seiten: 208
Inhalt: xii
194 S.
9 s/w Illustr.
15 farbige Illustr.
194 p. 24 illus.
15 illus. in color.
ISBN-13: 9783319127651
ISBN-10: 3319127659
Sprache: Englisch
Herstellernummer: 86260270
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Rodriguez-López, Raquel
Nóbrega, Clévio
Herausgeber: Clévio Nóbrega/Raquel Rodriguez-López
Auflage: 2014
Hersteller: Springer International Publishing
Springer International Publishing AG
Maße: 241 x 160 x 17 mm
Von/Mit: Raquel Rodriguez-López (u. a.)
Erscheinungsdatum: 30.12.2014
Gewicht: 0,483 kg
preigu-id: 105038870
Zusammenfassung

Offers a comprehensive review of efforts aimed at uncovering genetic variants associated with obesity

Reviews genome-wide association studies, along with studies on monogenic and polygenic obesity

Identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health, including nutrigenomics

Includes supplementary material: [...]

Inhaltsverzeichnis
Challenges in understanding development of obesity.- Monogenic forms of obesity.- Heterogeneous obesity syndromes: new strategies for diagnosis.- Genetic contribution: common forms of obesity.- The role of the GWAS identified FTO locus in regulating body size and composition.- Neural vulnerability factors that increase risk for weight gain: prevention and treatment implications.- Molecular mechanisms involved in the regulation of food intake.- Epigenetics of human obesity: a link between genetics and nutrition.- MicroRNAs in obesity and metabolism.- Obesity study: animal models.- From Homo obesus to Homo diabesus: neuroadipology insight.- Obesity and type 2 diabetes. ¿
Details
Erscheinungsjahr: 2014
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Seiten: 208
Inhalt: xii
194 S.
9 s/w Illustr.
15 farbige Illustr.
194 p. 24 illus.
15 illus. in color.
ISBN-13: 9783319127651
ISBN-10: 3319127659
Sprache: Englisch
Herstellernummer: 86260270
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Rodriguez-López, Raquel
Nóbrega, Clévio
Herausgeber: Clévio Nóbrega/Raquel Rodriguez-López
Auflage: 2014
Hersteller: Springer International Publishing
Springer International Publishing AG
Maße: 241 x 160 x 17 mm
Von/Mit: Raquel Rodriguez-López (u. a.)
Erscheinungsdatum: 30.12.2014
Gewicht: 0,483 kg
preigu-id: 105038870
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