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The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg ¿Hallmarks of Cancer¿ are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book¿s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed.
The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease
The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg ¿Hallmarks of Cancer¿ are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book¿s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed.
The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease
An updated perspective on cancer with a Development and Evolutionary perspective
Hallmarks of Cancer structured in 2 main arms: tumor-autonomous vs non-autonomous traits
Easy to read language, containing appealing illustrations, respecting the scientific accuracy
PREFACE
CHAPTER 1
Molecular and Cell Biology of Cancer when cells break the rules and hijack their own planet
CHAPTER 2
Cancer as an Evolutionary Process
CHAPTER 3
Cell signaling in cancer
Chapter 4
¿The cell cycle, cytoskeleton and cancer¿
CHAPTER 5
Genomic Instability: DNA Repair and Cancer
CHAPTER 6
Cell metabolism in cancer ¿ an energetic switch
CHAPTER 7
Cancer immunoediting and hijacking of the immune system
CHAPTER 8
Angiogenesis - vessels recruitment by tumor cells
CHAPTER 9
Tumor niche disruption and metastasis: the role of epithelial-mesenchymal transition (EMT)
CHAPTER 10
Case studies - Molecular Pathology perspective and impact on oncologic patients¿ management
INDEX
| Erscheinungsjahr: | 2019 |
|---|---|
| Fachbereich: | Therapie |
| Genre: | Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Taschenbuch |
| Seiten: | 228 |
| Reihe: | Learning Materials in Biosciences |
| Inhalt: |
ix
216 S. 71 farbige Illustr. 216 p. 71 illus. in color. |
| ISBN-13: | 9783030118112 |
| ISBN-10: | 3030118118 |
| Sprache: | Englisch |
| Herstellernummer: | 978-3-030-11811-2 |
| Ausstattung / Beilage: | Paperback |
| Einband: | Kartoniert / Broschiert |
| Redaktion: |
Zilhão, Rita
Fior, Rita |
| Herausgeber: | Rita Fior/Rita Zilhão |
| Auflage: | 1st ed. 2019 |
| Hersteller: |
Springer International Publishing
Springer International Publishing AG Learning Materials in Biosciences |
| Maße: | 240 x 168 x 12 mm |
| Von/Mit: | Rita Zilhão (u. a.) |
| Erscheinungsdatum: | 08.07.2019 |
| Gewicht: | 0,443 kg |
An updated perspective on cancer with a Development and Evolutionary perspective
Hallmarks of Cancer structured in 2 main arms: tumor-autonomous vs non-autonomous traits
Easy to read language, containing appealing illustrations, respecting the scientific accuracy
PREFACE
CHAPTER 1
Molecular and Cell Biology of Cancer when cells break the rules and hijack their own planet
CHAPTER 2
Cancer as an Evolutionary Process
CHAPTER 3
Cell signaling in cancer
Chapter 4
¿The cell cycle, cytoskeleton and cancer¿
CHAPTER 5
Genomic Instability: DNA Repair and Cancer
CHAPTER 6
Cell metabolism in cancer ¿ an energetic switch
CHAPTER 7
Cancer immunoediting and hijacking of the immune system
CHAPTER 8
Angiogenesis - vessels recruitment by tumor cells
CHAPTER 9
Tumor niche disruption and metastasis: the role of epithelial-mesenchymal transition (EMT)
CHAPTER 10
Case studies - Molecular Pathology perspective and impact on oncologic patients¿ management
INDEX
| Erscheinungsjahr: | 2019 |
|---|---|
| Fachbereich: | Therapie |
| Genre: | Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Taschenbuch |
| Seiten: | 228 |
| Reihe: | Learning Materials in Biosciences |
| Inhalt: |
ix
216 S. 71 farbige Illustr. 216 p. 71 illus. in color. |
| ISBN-13: | 9783030118112 |
| ISBN-10: | 3030118118 |
| Sprache: | Englisch |
| Herstellernummer: | 978-3-030-11811-2 |
| Ausstattung / Beilage: | Paperback |
| Einband: | Kartoniert / Broschiert |
| Redaktion: |
Zilhão, Rita
Fior, Rita |
| Herausgeber: | Rita Fior/Rita Zilhão |
| Auflage: | 1st ed. 2019 |
| Hersteller: |
Springer International Publishing
Springer International Publishing AG Learning Materials in Biosciences |
| Maße: | 240 x 168 x 12 mm |
| Von/Mit: | Rita Zilhão (u. a.) |
| Erscheinungsdatum: | 08.07.2019 |
| Gewicht: | 0,443 kg |
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