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Medicinal Chemistry
Taschenbuch von Donna M Huryn (u. a.)
Sprache: Englisch

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Beschreibung

Medicinal Chemistry teaches the essential concepts of medicinal chemistry from the perspective of practicing chemists, starting with a synthetic organic chemistry and structural biology foundation and interweaving coverage of therapeutics, case studies, historical context, and modern techniques. It is intended for advanced undergraduates and first-year graduate students in biology, chemistry, and biochemistry taking a one-semester survey course in medicinal chemistry.

Medicinal Chemistry teaches the essential concepts of medicinal chemistry from the perspective of practicing chemists, starting with a synthetic organic chemistry and structural biology foundation and interweaving coverage of therapeutics, case studies, historical context, and modern techniques. It is intended for advanced undergraduates and first-year graduate students in biology, chemistry, and biochemistry taking a one-semester survey course in medicinal chemistry.

Über den Autor
Norma Dunlap is Professor of Chemistry at Middle Tennessee State University, where she specializes in synthetic organic chemistry and medicinal chemistry. Her research interests include the design and synthesis of bioactive compounds, as well as isolation, identification, and synthesis of bioactive natural products. She holds a PhD in Organic Chemistry from the University of Wyoming and was an NIH Postdoctoral Fellow at the University of Pennsylvania. Prior to an academic career, she was a Senior Research Scientist in drug discovery at Hoffmann-LaRoche.Donna M. Huryn is Research Professor in the Department of Pharmaceutical Sciences at the University of Pittsburgh and Adjunct Professor of Chemistry at the University of Pennsylvania and. Her research focuses on identi_cation, characterization, and optimization of small molecule probes and drugs to treat cancer, neurodegeneration and infectious diseases. She holds a PhD from the University of Pennsylvania and started her career as a medicinal chemist in the pharmaceutical industry. She is the Principal Investigator of the University of Pittsburgh Chemical Diversity Center and is a Fellow of the American Chemical Society.
Inhaltsverzeichnis

PART I: Drug Discovery and Development 1. Historical Perspective and Overview of Drug Discovery 2. Drug discovery: Hit and Lead Discovery 3. Drug Discovery: Optimization of Lead Properties PART II: Classes of Drug Targets 4. Medicinal Chemistry Strategies Used in Lead Optimization 5. The Process of Developing a Drug from an Optimized Lead 6. Receptors as Drug Targets 7. Enzymes as Drug Targets 8. Protein-Protein Interactions and Lipids as Drug Targets 9. DNA and RNA as Drug Targets PART III: Selected Therapeutic Areas 10. Anti-Cancer Drugs 11. Infectious Diseases I: Antiviral and Antifungal Drugs 12. Infectious Diseases II: Antibacterial and Antiparasitic Drugs 13. Drugs Acting on the CNS

Details
Erscheinungsjahr: 2018
Fachbereich: Toxikologie
Genre: Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
Seiten: 508
Inhalt: Einband - flex.(Paperback)
ISBN-13: 9780815345565
ISBN-10: 0815345569
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Huryn, Donna M
Dunlap, Norma K
Hersteller: Taylor & Francis Inc
Maße: 213 x 275 x 30 mm
Von/Mit: Donna M Huryn (u. a.)
Erscheinungsdatum: 17.04.2018
Gewicht: 1,162 kg
preigu-id: 113982651
Über den Autor
Norma Dunlap is Professor of Chemistry at Middle Tennessee State University, where she specializes in synthetic organic chemistry and medicinal chemistry. Her research interests include the design and synthesis of bioactive compounds, as well as isolation, identification, and synthesis of bioactive natural products. She holds a PhD in Organic Chemistry from the University of Wyoming and was an NIH Postdoctoral Fellow at the University of Pennsylvania. Prior to an academic career, she was a Senior Research Scientist in drug discovery at Hoffmann-LaRoche.Donna M. Huryn is Research Professor in the Department of Pharmaceutical Sciences at the University of Pittsburgh and Adjunct Professor of Chemistry at the University of Pennsylvania and. Her research focuses on identi_cation, characterization, and optimization of small molecule probes and drugs to treat cancer, neurodegeneration and infectious diseases. She holds a PhD from the University of Pennsylvania and started her career as a medicinal chemist in the pharmaceutical industry. She is the Principal Investigator of the University of Pittsburgh Chemical Diversity Center and is a Fellow of the American Chemical Society.
Inhaltsverzeichnis

PART I: Drug Discovery and Development 1. Historical Perspective and Overview of Drug Discovery 2. Drug discovery: Hit and Lead Discovery 3. Drug Discovery: Optimization of Lead Properties PART II: Classes of Drug Targets 4. Medicinal Chemistry Strategies Used in Lead Optimization 5. The Process of Developing a Drug from an Optimized Lead 6. Receptors as Drug Targets 7. Enzymes as Drug Targets 8. Protein-Protein Interactions and Lipids as Drug Targets 9. DNA and RNA as Drug Targets PART III: Selected Therapeutic Areas 10. Anti-Cancer Drugs 11. Infectious Diseases I: Antiviral and Antifungal Drugs 12. Infectious Diseases II: Antibacterial and Antiparasitic Drugs 13. Drugs Acting on the CNS

Details
Erscheinungsjahr: 2018
Fachbereich: Toxikologie
Genre: Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
Seiten: 508
Inhalt: Einband - flex.(Paperback)
ISBN-13: 9780815345565
ISBN-10: 0815345569
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Huryn, Donna M
Dunlap, Norma K
Hersteller: Taylor & Francis Inc
Maße: 213 x 275 x 30 mm
Von/Mit: Donna M Huryn (u. a.)
Erscheinungsdatum: 17.04.2018
Gewicht: 1,162 kg
preigu-id: 113982651
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