Zum Hauptinhalt springen Zur Suche springen Zur Hauptnavigation springen
Beschreibung
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.
Über den Autor
Bradley Efron is Max H. Stein Professor of Statistics and Biostatistics at the Stanford University School of Humanities and Sciences, and the Department of Health Research and Policy with the School of Medicine.
Inhaltsverzeichnis
Introduction and foreword; 1. Empirical Bayes and the James-Stein estimator; 2. Large-scale hypothesis testing; 3. Significance testing algorithms; 4. False discovery rate control; 5. Local false discovery rates; 6. Theoretical, permutation and empirical null distributions; 7. Estimation accuracy; 8. Correlation questions; 9. Sets of cases (enrichment); 10. Combination, relevance, and comparability; 11. Prediction and effect size estimation; A. Exponential families; B. Programs and data sets; Bibliography; Index.
Details
Erscheinungsjahr: 2014
Fachbereich: Wahrscheinlichkeitstheorie
Genre: Importe, Mathematik
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
ISBN-13: 9781107619678
ISBN-10: 110761967X
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Efron, Bradley
Hersteller: Cambridge University Press
Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de
Maße: 229 x 152 x 15 mm
Von/Mit: Bradley Efron
Erscheinungsdatum: 28.02.2014
Gewicht: 0,404 kg
Artikel-ID: 106052270

Ähnliche Produkte

Buch
Buch