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Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology. A proven and popular textbook for upper-level undergraduates and graduate students, this fifth edition remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology. A proven and popular textbook for upper-level undergraduates and graduate students, this fifth edition remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Tom Strachan is Emeritus Professor of Human Molecular Genetics at Newcastle University, Newcastle, UK, and is a Fellow of the Royal Society of Edinburgh and a Fellow of the Academy of Medical Sciences. He was the founding Head of Institute at Newcastle University's Institute of Human Genetics (now the Institute of Genetic Medicine) and its Scientific Director from 2001 to 2009. Tom's early research interests were in multigene family evolution and interlocus sequence exchange, notably in the HLA and 21-hydroxylase gene clusters. While pursuing the latter, he became interested in medical genetics. His most recent research has focused on developmental disorders and developmental control genes.
Andrew Read
Drs. Strachan and Read were recipients of the European Society of Human Genetics Education Award
Part 1: Basics of DNA, Chromosomes, Cells, Development and Inheritance. 1. Basic Principles of Nucleic Acid Structure and Gene Expression. 2. Fundamentals of Cells and Chromosomes. 3. Fundamentals of Cell-Cell Interactions and Immune System Biology. 4. Aspects of Early Mammalian Development, Cell Differentiation, and Stem Cells. 5. Patterns of Inheritance. Part 2: Understanding Genomes. 6. Core DNA Technologies: Amplifying DNA, Nucleic Acid Hybridization, and DNA Sequencing. 7. Analyzing the Structure and Expression of Genes and Genomes. 8. Principles of Genetic Manipulation of Mammalian Cells. 9. Uncovering the Architecture and Workings of the Human Genome. 10. Gene Regulation and the Epigenome. Part 3: Genetic Variation between Individuals and Species. 11. An Overview of Human Genetic Variation. 12. Human Population Genetics. 13. Comparative Genomics and Genome Evolution. 14. Human Evolution. Part 4: Human Genetic Disease. 15. Chromosomal Abnormalities and Structural Variants. 16. Molecular Pathology: Connecting Phenotypes to Genotypes. 17. Mapping and Identifying Genes for Monogenic Disorders. 18. Complex Disease: Identifying Susceptibility Factors and Understanding Pathogenesis. 19. Cancer Genetics and Genomics. Part 5: Applied Human Molecular Genetics. 20. Genetic Testing in Healthcare and the Law. 21. Model Organisms and Modeling Disease. 22. Genetic Approaches to Treating Disease.
Erscheinungsjahr: | 2019 |
---|---|
Fachbereich: | Gentechnologie |
Genre: | Biologie |
Rubrik: | Naturwissenschaften & Technik |
Medium: | Buch |
Seiten: | 784 |
Inhalt: | Einband - fest (Hardcover) |
ISBN-13: | 9780367002503 |
ISBN-10: | 0367002507 |
Sprache: | Englisch |
Einband: | Gebunden |
Autor: | Strachan, Tom |
Hersteller: | Taylor & Francis Ltd |
Maße: | 219 x 285 x 39 mm |
Von/Mit: | Tom Strachan |
Erscheinungsdatum: | 11.01.2019 |
Gewicht: | 2,526 kg |
Tom Strachan is Emeritus Professor of Human Molecular Genetics at Newcastle University, Newcastle, UK, and is a Fellow of the Royal Society of Edinburgh and a Fellow of the Academy of Medical Sciences. He was the founding Head of Institute at Newcastle University's Institute of Human Genetics (now the Institute of Genetic Medicine) and its Scientific Director from 2001 to 2009. Tom's early research interests were in multigene family evolution and interlocus sequence exchange, notably in the HLA and 21-hydroxylase gene clusters. While pursuing the latter, he became interested in medical genetics. His most recent research has focused on developmental disorders and developmental control genes.
Andrew Read
Drs. Strachan and Read were recipients of the European Society of Human Genetics Education Award
Part 1: Basics of DNA, Chromosomes, Cells, Development and Inheritance. 1. Basic Principles of Nucleic Acid Structure and Gene Expression. 2. Fundamentals of Cells and Chromosomes. 3. Fundamentals of Cell-Cell Interactions and Immune System Biology. 4. Aspects of Early Mammalian Development, Cell Differentiation, and Stem Cells. 5. Patterns of Inheritance. Part 2: Understanding Genomes. 6. Core DNA Technologies: Amplifying DNA, Nucleic Acid Hybridization, and DNA Sequencing. 7. Analyzing the Structure and Expression of Genes and Genomes. 8. Principles of Genetic Manipulation of Mammalian Cells. 9. Uncovering the Architecture and Workings of the Human Genome. 10. Gene Regulation and the Epigenome. Part 3: Genetic Variation between Individuals and Species. 11. An Overview of Human Genetic Variation. 12. Human Population Genetics. 13. Comparative Genomics and Genome Evolution. 14. Human Evolution. Part 4: Human Genetic Disease. 15. Chromosomal Abnormalities and Structural Variants. 16. Molecular Pathology: Connecting Phenotypes to Genotypes. 17. Mapping and Identifying Genes for Monogenic Disorders. 18. Complex Disease: Identifying Susceptibility Factors and Understanding Pathogenesis. 19. Cancer Genetics and Genomics. Part 5: Applied Human Molecular Genetics. 20. Genetic Testing in Healthcare and the Law. 21. Model Organisms and Modeling Disease. 22. Genetic Approaches to Treating Disease.
Erscheinungsjahr: | 2019 |
---|---|
Fachbereich: | Gentechnologie |
Genre: | Biologie |
Rubrik: | Naturwissenschaften & Technik |
Medium: | Buch |
Seiten: | 784 |
Inhalt: | Einband - fest (Hardcover) |
ISBN-13: | 9780367002503 |
ISBN-10: | 0367002507 |
Sprache: | Englisch |
Einband: | Gebunden |
Autor: | Strachan, Tom |
Hersteller: | Taylor & Francis Ltd |
Maße: | 219 x 285 x 39 mm |
Von/Mit: | Tom Strachan |
Erscheinungsdatum: | 11.01.2019 |
Gewicht: | 2,526 kg |