Presents in a single volume an up-to-date summary of both basic science and clinical research with actual practical consequences.

Provides population-based strategies for H. pylori-associated disease management including European, Latin American, and Asian perspectives.

Covers the roles of all reported virulence factors of H. pylori on pathogenesis

PART 1 BACTERIOLOGY AND MOLECULAR BIOLOGY.- 1 Helicobacter pylori: genetics, recombination, population structure and human migrations.- 2 Adaptation of Helicobacter pylori metabolism to persistent gastric colonization.- 3 Virulence mechanisms of Helicobacter pylori: an overview.- 4 Roles of the cagPAI and CagA on gastroduodenal diseases.- 5 Helicobacter pylori vacuolating toxin.- 6 Roles of the BabA and the SabA adhesins in gastroduodenal diseases.- 7 Emerging novel virulence factors of Helicobacter pylori.- 8 The primary transcriptome and non-coding RNA repertoire of Helicobacter pylori.- 9 Genome evolution: Helicobacter pylori as an extreme model.- 10 Non-Helicobacter pylori Helicobacter infections in humans and animals.- PART 2 IMMUNE RESPONSES AND HOST FACTORS.- 11 Animal Models of Helicobacter pylori Infection.- 12 Helicobacter pylori and the host immune response.- 13 The role of inflammatory responses in mouse gastric tumorigenesis.- 14 Influence of host gene polymorphisms ondevelopment of gastroduodenal diseases.- PART 3 HELICOBACTER PYLORI-ASSOCIATED DISEASES.- 15 Helicobacter pylori and Nonmalignant Diseases.- 16 Helicobacter pylori and gastrointestinal polyps.- 17 Helicobacter pylori infection and gastric cancer.- 18 Helicobacter pylori infection and MALT lymphoma.- 19 Helicobacter pylori infection in children.- PART 4 TREATMENT OF HELICOBACTER PYLORI.- 20 Helicobacter pylori therapy.- 21 Management of H. pylori infection in Europe.- 22 Population-based strategies for Helicobacter pylori-associated disease management: Latin American perspective.- 23 Population-based strategies for Helicobacter pylori-associated disease management: Asian perspective.- 24 Probiotics as an alternative therapy for Helicobacter pylori-associated diseases.- 25 Vaccination against Helicobacter pylori infection.