Professor?Charles Brook is one of the UK and Europe's most prominent endocrinologists. He is Emeritus Professor of Paediatric Endocrinology at University College London and honorary consulting paediatric endocrinologist to Great Ormond Street and University College London Hospitals. He has had over?300 articles published.

Professor Mehul Dattani is Academic and Clinical Lead in Endocrinology at Great Ormond Street Hospital for Children (GOSH) and ICH. His?research has led to publications in a number of high impact journals, with 74 articles appearing on PubMed.

List of Abbreviations, ix

1 The Relevance of Molecular Biology to Clinical Practice , 1

2 Hormones: their Nature, Action and Measurement , 15

3 The Hypothalamo-Pituitary Axis , 31

4 Endocrine Problems of Infancy , 48

5 The Management of Growth Disorders , 70

6 The Management of Puberty Disorders , 99

7 The Thyroid Gland , 129

8 The Adrenal Gland , 151

9 Disorders of Calcium and Bone Metabolism , 175

10 Water Balance , 210

11 Hypoglycemia , 230

12 Obesity and Type 2 Diabetes Mellitus , 248

13 Type 1 Diabetes Mellitus , 267

14 Endocrine Neoplasia, 296

15 Tests and Normal Values in Pediatric Endocrinology , 309

Appendix 1: Syndrome-Specific Growth Charts , 325

Appendix 2: Normal Values , 337

Index, 343