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Genome-Scale Algorithm Design
Bioinformatics in the Era of High-Throughput Sequencing
Buch von Veli Mäkinen (u. a.)
Sprache: Englisch

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Beschreibung
"Guided by standard bioscience workflows in high-throughput sequencing analysis, this book for graduate students, researchers, and professionals in bioinformatics and computer science offers a unified presentation of genome-scale algorithms. This new edition covers the use of minimizers and other advanced data structures in pangenomics approaches"--
"Guided by standard bioscience workflows in high-throughput sequencing analysis, this book for graduate students, researchers, and professionals in bioinformatics and computer science offers a unified presentation of genome-scale algorithms. This new edition covers the use of minimizers and other advanced data structures in pangenomics approaches"--
Über den Autor
Veli Mäkinen is Professor of Computer Science at the University of Helsinki, where he leads a research team on genome-scale algorithmics. He has taught advanced courses on algorithm design and analysis, string processing, data compression, and algorithmic genome analysis, as well as introductory courses on bioinformatics.
Inhaltsverzeichnis
Part I. Preliminaries: 1. Molecular biology and high-throughput sequencing; 2. Algorithm design; 3. Data structures; 4. Graphs; 5. Network flows; Part II. Fundamentals of Biological Sequence Analysis: 6. Alignments; 7. Hidden Markov models; Part III. Genome-Scale Index Structures: 8. Classical indexes; 9. Burrows¿Wheeler indexes; Part IV. Genome-Scale Algorithms: 10. Alignment-based genome analysis; 11. Alignment-free genome analysis and comparison; 12. Compression of genome collections; 13. Fragment assembly; Part V. Applications: 14. Haplotype analysis; 15. Pangenomics; 16. Transcriptomics; 17. Metagenomics; References; Index.
Details
Erscheinungsjahr: 2023
Genre: Informatik
Rubrik: Naturwissenschaften & Technik
Medium: Buch
ISBN-13: 9781009341233
ISBN-10: 1009341235
Sprache: Englisch
Einband: Gebunden
Autor: Mäkinen, Veli
Belazzougui, Djamal
Cunial, Fabio
Tomescu, Alexandru I
Auflage: 2nd edition
Hersteller: Greenwich Medical Media
Maße: 250 x 171 x 31 mm
Von/Mit: Veli Mäkinen (u. a.)
Erscheinungsdatum: 12.10.2023
Gewicht: 0,98 kg
Artikel-ID: 126944900
Über den Autor
Veli Mäkinen is Professor of Computer Science at the University of Helsinki, where he leads a research team on genome-scale algorithmics. He has taught advanced courses on algorithm design and analysis, string processing, data compression, and algorithmic genome analysis, as well as introductory courses on bioinformatics.
Inhaltsverzeichnis
Part I. Preliminaries: 1. Molecular biology and high-throughput sequencing; 2. Algorithm design; 3. Data structures; 4. Graphs; 5. Network flows; Part II. Fundamentals of Biological Sequence Analysis: 6. Alignments; 7. Hidden Markov models; Part III. Genome-Scale Index Structures: 8. Classical indexes; 9. Burrows¿Wheeler indexes; Part IV. Genome-Scale Algorithms: 10. Alignment-based genome analysis; 11. Alignment-free genome analysis and comparison; 12. Compression of genome collections; 13. Fragment assembly; Part V. Applications: 14. Haplotype analysis; 15. Pangenomics; 16. Transcriptomics; 17. Metagenomics; References; Index.
Details
Erscheinungsjahr: 2023
Genre: Informatik
Rubrik: Naturwissenschaften & Technik
Medium: Buch
ISBN-13: 9781009341233
ISBN-10: 1009341235
Sprache: Englisch
Einband: Gebunden
Autor: Mäkinen, Veli
Belazzougui, Djamal
Cunial, Fabio
Tomescu, Alexandru I
Auflage: 2nd edition
Hersteller: Greenwich Medical Media
Maße: 250 x 171 x 31 mm
Von/Mit: Veli Mäkinen (u. a.)
Erscheinungsdatum: 12.10.2023
Gewicht: 0,98 kg
Artikel-ID: 126944900
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