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Genetics of Melanoma
Buch von Jonathan L. Curry (u. a.)
Sprache: Englisch

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Beschreibung
This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.
This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.
Über den Autor
Carlos A. Torres-Cabala, MD, Associate Professor of Pathology and Dermatology, Chief of Dermatopathology Section, The University of Texas MD Anderson Cancer Center, Houston, TX
Jonathan L. Curry, MD, Associate Professor of Pathology and Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX
Inhaltsverzeichnis

Biology of Melanoma.- The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma.- Epidemiology and Clinical Characteristics of Melanoma.- Pathology of Melanoma.- Inherited Gene Mutations in Melanoma.- The MAPK Pathway in Melanoma.- The PI3K-AKT Pathway in Melanoma.- Biomarker Analysis for BRAF, NRAS, KIT, and BAP-1 Expression in Melanoma.- Molecular Platforms in Melanoma Mutation Analysis.- Immunotherapy in Melanoma.- Molecular Targeted Therapy in Melanoma.- Dermatologic Toxicities to Melanoma Targeted Therapy.

Details
Erscheinungsjahr: 2016
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Reihe: Cancer Genetics
Inhalt: xv
288 S.
1 s/w Illustr.
53 farbige Illustr.
288 p. 54 illus.
53 illus. in color.
ISBN-13: 9781493935529
ISBN-10: 1493935526
Sprache: Englisch
Herstellernummer: 978-1-4939-3552-9
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Curry, Jonathan L.
Torres-Cabala, Carlos A.
Herausgeber: Carlos A Torres-Cabala/Jonathan L Curry
Auflage: 1st ed. 2016
Hersteller: Springer US
Springer New York
Springer US, New York, N.Y.
Cancer Genetics
Maße: 241 x 160 x 22 mm
Von/Mit: Jonathan L. Curry (u. a.)
Erscheinungsdatum: 12.05.2016
Gewicht: 0,623 kg
Artikel-ID: 104085689
Über den Autor
Carlos A. Torres-Cabala, MD, Associate Professor of Pathology and Dermatology, Chief of Dermatopathology Section, The University of Texas MD Anderson Cancer Center, Houston, TX
Jonathan L. Curry, MD, Associate Professor of Pathology and Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX
Inhaltsverzeichnis

Biology of Melanoma.- The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma.- Epidemiology and Clinical Characteristics of Melanoma.- Pathology of Melanoma.- Inherited Gene Mutations in Melanoma.- The MAPK Pathway in Melanoma.- The PI3K-AKT Pathway in Melanoma.- Biomarker Analysis for BRAF, NRAS, KIT, and BAP-1 Expression in Melanoma.- Molecular Platforms in Melanoma Mutation Analysis.- Immunotherapy in Melanoma.- Molecular Targeted Therapy in Melanoma.- Dermatologic Toxicities to Melanoma Targeted Therapy.

Details
Erscheinungsjahr: 2016
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Reihe: Cancer Genetics
Inhalt: xv
288 S.
1 s/w Illustr.
53 farbige Illustr.
288 p. 54 illus.
53 illus. in color.
ISBN-13: 9781493935529
ISBN-10: 1493935526
Sprache: Englisch
Herstellernummer: 978-1-4939-3552-9
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Curry, Jonathan L.
Torres-Cabala, Carlos A.
Herausgeber: Carlos A Torres-Cabala/Jonathan L Curry
Auflage: 1st ed. 2016
Hersteller: Springer US
Springer New York
Springer US, New York, N.Y.
Cancer Genetics
Maße: 241 x 160 x 22 mm
Von/Mit: Jonathan L. Curry (u. a.)
Erscheinungsdatum: 12.05.2016
Gewicht: 0,623 kg
Artikel-ID: 104085689
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