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current understanding about the biology and patho-biology of cardiomyocytes and
depicts common techniques for the study of these cells. The
book is divided into two parts; the first part provides insight into role and
function of cardiomyocytes under normal conditions and describes embryogenesis
and differentiation, in the second part the role of cardiomyocytes in aging and
disease is discussed and cellular responses under stress conditions illustrated.
Cardiomyocytes represent
the main mass of the heart, and cellular malfunction directly modifies heart
function leading to subsequent heart failure. As such, cardiomyocytes are
causative involved in the main reasons of heart failure, such as post-infarct
remodeling, hypertensive heart disease, idiopathic heart failure, and
interactions with other co-morbidities such as diabetes. On the other hand,
cardiomyocytes are necessarily target of therapy. Therefore, a precise
understanding of cardiomyocytes biology is a pre-requisite for proper disease
treatment and evidence based medicine.
The book is written for
cell biologists, pharmacologists and biomedical researchers specialized in
cardiac and vascular biology.
current understanding about the biology and patho-biology of cardiomyocytes and
depicts common techniques for the study of these cells. The
book is divided into two parts; the first part provides insight into role and
function of cardiomyocytes under normal conditions and describes embryogenesis
and differentiation, in the second part the role of cardiomyocytes in aging and
disease is discussed and cellular responses under stress conditions illustrated.
Cardiomyocytes represent
the main mass of the heart, and cellular malfunction directly modifies heart
function leading to subsequent heart failure. As such, cardiomyocytes are
causative involved in the main reasons of heart failure, such as post-infarct
remodeling, hypertensive heart disease, idiopathic heart failure, and
interactions with other co-morbidities such as diabetes. On the other hand,
cardiomyocytes are necessarily target of therapy. Therefore, a precise
understanding of cardiomyocytes biology is a pre-requisite for proper disease
treatment and evidence based medicine.
The book is written for
cell biologists, pharmacologists and biomedical researchers specialized in
cardiac and vascular biology.
Institute of Physiology
JLU Giessen
Giessen, Germany
Provides a comprehensive insight into cardiomyocyte function and dysfunction
Readers will learn about common techniques and analysis
Experts depict regeneration capacities and possibilities of cardiac protection
Gives a broad overview on cardiomyocyte biology
Cardiomyocytes: Function and Regeneration.- [...] to study the biology of cardiomyocytes.-
2.Cardiomyocytes: Function and Regeneration.- 3.Excitation-contraction coupling
of cardiomyocytes.- 4.Cardiac metabolism and energetic control.- 5.Endogenous
mechanisms for regulating myocardial contractility.- Cardiomyocytes in ageing,
disease, and protection.- 6.Growth regulation of cardiomyocytes: Control of
cell size and its role in cardiac hypertrophy.- 7.Protein Degradation in
Cardiomyocytes - Target Proteins and clinical consequences.- 8.Ischemia and
Reperfusion.- 9.Mechanisms of cardiac cell death.- 10.Oxidative stress and
nitrosative stress.
| Erscheinungsjahr: | 2018 |
|---|---|
| Fachbereich: | Allgemeines |
| Genre: | Biologie, Mathematik, Medizin, Naturwissenschaften, Technik |
| Rubrik: | Naturwissenschaften & Technik |
| Thema: | Lexika |
| Medium: | Taschenbuch |
| Inhalt: |
xv
278 S. 27 s/w Illustr. 13 farbige Illustr. 278 p. 40 illus. 13 illus. in color. |
| ISBN-13: | 9783319809991 |
| ISBN-10: | 3319809997 |
| Sprache: | Englisch |
| Einband: | Kartoniert / Broschiert |
| Redaktion: | Schlüter, Klaus-Dieter |
| Herausgeber: | Klaus-Dieter Schlüter |
| Auflage: | Softcover reprint of the original 1st edition 2016 |
| Hersteller: |
Springer International Publishing
Springer International Publishing AG |
| Verantwortliche Person für die EU: | Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com |
| Maße: | 235 x 155 x 16 mm |
| Von/Mit: | Klaus-Dieter Schlüter |
| Erscheinungsdatum: | 30.05.2018 |
| Gewicht: | 0,506 kg |
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