B Cells in Immunity and Tolerance

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Sprache: Englisch

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Beschreibung

This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.

Über den Autor

Dr. Ji-Yang Wang is a professor at Department of Immunology, School of Basic Medical Sciences, Fudan University, China. He was recruited to the 1000Talents Program of Shanghai in 2013. Prof. Wang's research focuses on B cell development, activation and differentiation, and B cell-related diseases. He has published more than 100 articles on international journals in these fields.

Zusammenfassung

Providing with the cutting-edge developments in all aspects of B cell biology

Covering human B cell related diseases

Serving as a routine and standard reference for both basic researchers and clinicians

Inhaltsverzeichnis

B cell development and maturation.- B cell receptor signalling.- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger.- Germinal center reaction.- Memory B cells in local and systemic sites.- Regulation of plasma cell differentiation.- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor.- Regulatory B cells.- Diversified IgA-bacteria interaction in gut homeostasis.- Primary antibody deficiencies.- B cell-mediated autoimmune diseases.- B cell lymphomas.

Details

Erscheinungsjahr:	2021
Fachbereich:	Therapie
Genre:	Medizin
Rubrik:	Wissenschaften
Medium:	Taschenbuch
Reihe:	Advances in Experimental Medicine and Biology
Inhalt:	xii 181 S. 5 s/w Illustr. 30 farbige Illustr. 181 p. 35 illus. 30 illus. in color.
ISBN-13:	9789811535345
ISBN-10:	9811535345
Sprache:	Englisch
Ausstattung / Beilage:	Paperback
Einband:	Kartoniert / Broschiert
Redaktion:	Wang, Ji-Yang
Herausgeber:	Ji-Yang Wang
Auflage:	1st ed. 2020
Hersteller:	Springer Nature Singapore Springer Malaysia Representative Office Advances in Experimental Medicine and Biology
Maße:	254 x 178 x 11 mm
Von/Mit:	Ji-Yang Wang
Erscheinungsdatum:	23.04.2021
Gewicht:	0,38 kg

Artikel-ID: 119749812