NIR BARZILAI, M.D., is the founding Director of the Institute for Aging Research at Albert Einstein College of Medicine and the Nathan Shock Center for Excellence in the Basic Biology of Aging and the Einstein Glenn Center for the Biology of Human Aging. He is also the Scientific Director of the American Federation for Aging Research (AFAR). Dr. Barzilai discovered the first longevity gene in humans and has since discovered several others, and he is the co-founder of CohBar, a clinical stage biotechnology company focused on increasing health span by developing treatments for age-related diseases. Age Later is his first publication for consumers.

Introduction
1. One Hundred Years YoungThe Mysteries of Aging
What Makes SuperAgers Stay Healthy?
Studying Centenarians
Designing a Study Without a Control Group
Meeting Our First AJ Centenarians and Their Offspring
A Perfect Genome?
Centenarians' Interactions with Their Environments
Do as I Say, Not as I Do

2. Why We Age
Recent Theories
The Search for Protection from Aging
Eating Less May Lead to More Healthy Years
Unlocking the Secrets in Fat
Caloric Restriction: A Mixed Bag of Effects
Aging Begins Before We're Born
SuperAgers' Top Secrets

3. Cholesterol: Is More Better?
Unlocking Cholesterol's Longevity Secrets
Are there Really Good Gene Mutations?
Solving the Mystery of Helpful Gene Mutations
The Benefits of CETP Personified
A Mutation That Adds Years to Life Span?

4. Growth Hormone: Less Is More
Less Growth May Lead to an Exceptionally Long Life
Growth Hormone Clues from Our Centenarians
Epigenetic Mechanisms Can Increase Longevity
Making the Most of Our Findings
Growth Hormones Don't "Grow" Life Span

5. Unraveling the Longevity Mystery Deep Inside Our Cells
A Match Made on Earth
Mitochondria's Hidden Purpose
Resilient to the End
A CohBar Is Born
Searching for Promising Peptides

6. The Quest to Prove Aging Can Be Targeted
Choosing an Existing Drug to Prove Our Point
Getting the FDA on Board
How the TAME Study Works
Who's Going to Pay for All This?
Metformin Is the Tool, Not the Goal

7. Making Eighty the New Sixty
The Price of Progress
Collaboration Is the Key to Speed
Long, Healthy Life Span Versus Immortality
The Gap Between Making Drugs and Making Drugs Available

8. Stop the Clock
How Old Is Old?
Use It or Lose It
Antioxidants and Hormesis
Thriving in the Shadow of Stress
Preventing the Loss of Muscle Mass as We Age
Exercise Plus Metformin
Feeding Our Longevity
Hydrating Wisely
Prevent Obesity
Nutraceuticals Are in the Works
The Magic Pills We've Been Wishing For
When We Eat Matters
Our DNA Has Something to Say
Stay Mentally Sharp
Other Promising Practices
How to Decide What's Good for You

9. Bright Horizons
The Unparalleled Power of Omics
Personalized Medicine
Advances in Early Detection
Pioneering Explorations
Reversing Cellular Age
Genetic Engineering

Acknowledgments
Index