The atomic structures of macromolecules provide the key to understanding how life works. Aaron Klug led the way in the development of methods for solving such structures and is one of the pioneers of structural molecular biology. He was awarded a Nobel Prize in 1982 for his work. Illuminating both his personal life and scientific achievements, this unique biography begins with Klug's youth in Durban and his studies at Johannesburg, Cape Town and then Trinity College, Cambridge. Holmes proceeds to explore Klug's career from his work on the structure of viruses with Rosalind Franklin at Birkbeck College, London to his time as Director of the MRC Laboratory of Molecular Biology (LMB) in Cambridge and as President of the Royal Society. Drawing on their long-term collaboration, interviews and unique access to Klug's archives, Holmes provides a fascinating account of an innovative man and his place in the history of structural molecular biology.
The atomic structures of macromolecules provide the key to understanding how life works. Aaron Klug led the way in the development of methods for solving such structures and is one of the pioneers of structural molecular biology. He was awarded a Nobel Prize in 1982 for his work. Illuminating both his personal life and scientific achievements, this unique biography begins with Klug's youth in Durban and his studies at Johannesburg, Cape Town and then Trinity College, Cambridge. Holmes proceeds to explore Klug's career from his work on the structure of viruses with Rosalind Franklin at Birkbeck College, London to his time as Director of the MRC Laboratory of Molecular Biology (LMB) in Cambridge and as President of the Royal Society. Drawing on their long-term collaboration, interviews and unique access to Klug's archives, Holmes provides a fascinating account of an innovative man and his place in the history of structural molecular biology.
Über den Autor
Kenneth C. Holmes is Emeritus Director of the Department of Biophysics at the Max Planck Institute for Medical Research (MPI), Heidelberg, Germany. He is a Fellow of the Royal Society and recipient of the Aminoff Prize, the Gabor Prize, and the European Latsis Prize. Holmes' long-term collaboration with Aaron Klug began in the late 1950s at Birkbeck College and continued at the Laboratory of Molecular Biology in Cambridge before his move to MPI in 1968.
Inhaltsverzeichnis
Foreword; Acknowledgements; Introduction; Part I. From Durban to Birkbeck College: 1. Durban and Johannesburg; 2. Cape Town; 3. Cambridge; 4. The first visit to Israel; 5. Back to Cambridge; 6. Birkbeck-1; 7. Birkbeck-2; Part II. Science at the Laboratory of Molecular Biology: 8. The Laboratory of Molecular Biology; 9. Spherical virus structure; 10. Tobacco mosaic virus; 11. From Thon rings to modern dance; 12. Tomography; 13. Transfer RNA; 14. Chromatin and nucleosomes; 15. Zinc fingers; Part III. Duties and Rewards: 16. Peterhouse; 17. Director of the Laboratory of Molecular Biology; 18. Presidency of the Royal Society; 19. Ben Gurion University; 20. Prizes; 21. Envoi; Appendicies: Appendix 1. Aaron's Birthplace - Zhelva, Lithuania Mark Gevisser; Appendix 2. Diffraction; Appendix 3. Aaron Klug's scientific publications; Index.
