Water, soil, plants, and animals are the main pillars that support global food security. Plants grow using nutrients from water and soil resources and then used by animals which affects them consequently. Water is the essential condition of life for all living beings, and soil is its support and a crucial reservoir. The interactions between the Water-Soil-Plant-Animal nexus and climate change are of increasing concern to scholars, decision-makers, and researchers. The impacts of climate change on these resources include water and soil quality degradation, infectious disease, shortage, desertification, and erosion. These impacts are accelerated due to human pressure through over-use and pollution. Water-Soil-Plant-Animal Nexus in the Era of Climate Change includes relevant theoretical approaches, empirical research, and bibliometric and bibliographic methods to bring together affordable methods and techniques to optimize the use of the nexus in the context of climate change. It presents an inventory of techniques and practices in the field, and introduces an opportunity to discuss the strengths and weaknesses of these techniques, making it ideal for scholars, researchers, planners, and decision-makers.