Two Photon Optogenetic Stimulation

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Sprache: Englisch

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Beschreibung

Stimulation of cells, especially neurons is of significant interest both for basic understanding of neuronal circuitry as well as clinical treatment. Existing electrode-based methods of stimulation is invasive and non-specific to single cells. Recently, optical stimulation of targeted neurons expressing light-sensitive proteins (opsins) has surfaced as an emerging and a powerful technique (Optogenetics) in neuroscience. Due to scattering and absorbance of light, optogenetic-based stimulation is also limited to the superficial regions. In order to achieve in-depth stimulation and efficient delivery of light, fiber-optic two photon optogenetics is helpful. The basic mechanism of two photon excitation and its analogous to channelrhodpsin-2 excitation has been discussed in this book. Fiber-optic two photon will allow in-depth localized stimulation for probing and manipulation of neural circuitry with high spatial resolution. Therefore, this book will shed some light on two photon optogenetic stimulation of cells and tissues and may be useful to anyone interested in this field.

Über den Autor

Dr.Dhakal received [...], [...].(Physics) from The Tribhuvan Univeristy Kathmandu Nepal, and MS, Ph.D. in Physics from The University of Texas at Arlington, USA. Dr. Dhakal has been involved in Teaching and research in various institutions.

Details

Erscheinungsjahr:	2016
Fachbereich:	Biophysik
Genre:	Biologie , Mathematik , Medizin , Naturwissenschaften , Technik
Rubrik:	Naturwissenschaften & Technik
Medium:	Taschenbuch
Inhalt:	72 S.
ISBN-13:	9783659895982
ISBN-10:	3659895989
Sprache:	Englisch
Ausstattung / Beilage:	Paperback
Einband:	Kartoniert / Broschiert
Autor:	Dhakal, Kamal
Hersteller:	LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU:	BoD - Books on Demand, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße:	220 x 150 x 5 mm
Von/Mit:	Kamal Dhakal
Erscheinungsdatum:	07.06.2016
Gewicht:	0,125 kg