Yasuo Hirai

Department of Obstetrics and GynecologyFaculty of Medicine

Dokkyo Medical University

Tochigi, Japan

PCL Japan Pathology and Cytology Center

PCL Inc.

Saitama

Japan

Franco Fulciniti

Clinical Cytology Service

Istituto Cantonale dì PatologiaEnte Ospedaliero CantonaleLocarno, Switzerland

Describes a method for classifying and reporting invasive endometrial malignancies via direct endometrial sampling

Provides specific diagnostic categories and cytomorphologic criteria to promote uniform and reliable diagnoses

For all researchers whose work involves gynecological cytology, oncology, pathology, and cytopathology

1 Endometrial Cytology in Historical Perspective.- 2 Overview of the Yokohama System for Reporting Endometrial Cytology.- 3 Pathogenetic Bases of the Yokohama System for Reporting Endometrial Cytology.- 4 Endometrial Cell Sampling Procedure to Obtain Cytologic Specimens.- 5 Algorithmic Interpretational and Diagnostic Approach to Endometrial Cytology for the Yokohama System.- 6 Evaluation of sample Adequacy: Cytologic criteria.- 7 Processing Methodology of Endometrial Cytology Samples.- 8 Negative for Malignant Tumors and Precursors: TYS1.- 9 Endometrial Hyperplasia without Atypia.- 10 Endometrial Atypical Hyperplasia / Endometrioid Intraepithelial Neoplasia.- 11 Malignant Neoplasms.- 12 Endometrial Glandular and Stromal Breakdown (EGBD) as Benign Mimics of Malignancy.- 13 Atypical Endometrial Cells (ATEC).- 14 Cell Block Techniques for Endometrial Cytology Technical Procedures, Role of Immunocytochemistry, Advantages, Applications.- 15 Molecular Pathology of EndometrialCarcinoma: A general appraisal.- 16 Molecular Pathology of Endometrial Carcinoma on LBC Samples and Cell Blocks.- 17 Future Challenges and Perspectives of Endometrial Cytology.- 18 The Future Direction in Endometrial Oncology Through the Liquid Biopsy.