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Cover: 9781402071447 | The Neurology of Neuroblastoma | Nina Felice Schor | Buch | VII | 2002
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The Neurology of Neuroblastoma
Neuroblastoma as a Neurobiological Disease
Buch von Nina Felice Schor
Sprache: Englisch

105,95 €*

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Versandkostenfrei per Post / DHL

Lieferzeit 2-3 Wochen

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Beschreibung
Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these children, the 5-year survival rate is only somewhere between 5% and 20% with therapies including surgery, radiation, chemotherapy, and bone marrow transplantation. Dr Schor outlines a new approach to these tumors in order to make a difference for these children. There is much information to support the notion that neuroblastomas represent a developmental aberration of the nervous system, rather than a de novo abnormality in a previously normal cell. While the remote, paraneoplastic effects of neuroblastoma are often the purview of the child neurologist, the neoplasm itself has been viewed and approached therapeutically in much the same manner as all other solid tumors, as the purview of the pediatric oncologist. This work takes the view that approaching neuroblastoma rather as a disorder of nervous system development offers new therapeutic possibilities for this common tumor of childhood.
Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these children, the 5-year survival rate is only somewhere between 5% and 20% with therapies including surgery, radiation, chemotherapy, and bone marrow transplantation. Dr Schor outlines a new approach to these tumors in order to make a difference for these children. There is much information to support the notion that neuroblastomas represent a developmental aberration of the nervous system, rather than a de novo abnormality in a previously normal cell. While the remote, paraneoplastic effects of neuroblastoma are often the purview of the child neurologist, the neoplasm itself has been viewed and approached therapeutically in much the same manner as all other solid tumors, as the purview of the pediatric oncologist. This work takes the view that approaching neuroblastoma rather as a disorder of nervous system development offers new therapeutic possibilities for this common tumor of childhood.
Inhaltsverzeichnis
1. Neural Crest Development.- 2. Apoptosis in the Nervous System.- 3. Neuroblastoma as a Clinical Entity.- 4. Paraneoplastic Syndromes and Neuroblastoma.- References.
Details
Erscheinungsjahr: 2002
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Seiten: 104
Inhalt: vii
90 S.
ISBN-13: 9781402071447
ISBN-10: 1402071442
Sprache: Englisch
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Autor: Schor, Nina Felice
Auflage: 2002
Hersteller: Springer US
Maße: 241 x 160 x 12 mm
Von/Mit: Nina Felice Schor
Erscheinungsdatum: 31.08.2002
Gewicht: 0,33 kg
preigu-id: 102922627
Inhaltsverzeichnis
1. Neural Crest Development.- 2. Apoptosis in the Nervous System.- 3. Neuroblastoma as a Clinical Entity.- 4. Paraneoplastic Syndromes and Neuroblastoma.- References.
Details
Erscheinungsjahr: 2002
Fachbereich: Andere Fachgebiete
Genre: Medizin
Rubrik: Wissenschaften
Medium: Buch
Seiten: 104
Inhalt: vii
90 S.
ISBN-13: 9781402071447
ISBN-10: 1402071442
Sprache: Englisch
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Autor: Schor, Nina Felice
Auflage: 2002
Hersteller: Springer US
Maße: 241 x 160 x 12 mm
Von/Mit: Nina Felice Schor
Erscheinungsdatum: 31.08.2002
Gewicht: 0,33 kg
preigu-id: 102922627
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