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Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data.
The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine.
Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine.
Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data.
The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine.
Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine.
| Erscheinungsjahr: | 2020 |
|---|---|
| Fachbereich: | Andere Fachgebiete |
| Genre: | Importe, Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Taschenbuch |
| ISBN-13: | 9781743057247 |
| ISBN-10: | 1743057245 |
| Sprache: | Englisch |
| Ausstattung / Beilage: | Paperback |
| Einband: | Kartoniert / Broschiert |
| Autor: |
Jureidini, Jon
Mchenry, Leemon B. |
| Hersteller: | Wakefield Press |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 234 x 156 x 18 mm |
| Von/Mit: | Jon Jureidini (u. a.) |
| Erscheinungsdatum: | 22.06.2020 |
| Gewicht: | 0,503 kg |
| Erscheinungsjahr: | 2020 |
|---|---|
| Fachbereich: | Andere Fachgebiete |
| Genre: | Importe, Medizin |
| Rubrik: | Wissenschaften |
| Medium: | Taschenbuch |
| ISBN-13: | 9781743057247 |
| ISBN-10: | 1743057245 |
| Sprache: | Englisch |
| Ausstattung / Beilage: | Paperback |
| Einband: | Kartoniert / Broschiert |
| Autor: |
Jureidini, Jon
Mchenry, Leemon B. |
| Hersteller: | Wakefield Press |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 234 x 156 x 18 mm |
| Von/Mit: | Jon Jureidini (u. a.) |
| Erscheinungsdatum: | 22.06.2020 |
| Gewicht: | 0,503 kg |
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