Section I. Clinical Psychological Science: An Evolving Field: 1. Trends in the evolving discipline of clinical psychology; 2. Defining and refining phenotypes: operational definitions as open concepts; 3. Building models of psychopathology spanning multiple modalities of measurements; Section II. Observational Approaches: 4. The conceptual foundations of descriptive psychopathology; 5. Survey and interview methods; 6. Psychometrics in clinical psychology research; 7. Latent variable models in clinical psychology; 8. Psychiatric epidemiology methods; Section III. Experimental and Biological Approaches: 9. Conceptual foundations of experimental psychopathology: historical context, scientific posture, and reflections on substantive and method matters; 10. A practical guide for designing and conducting cognitive studies in child psychopathology; 11. Peripheral psychophysiology; 12. Behavioral and molecular genetics; 13. Concepts and principles of clinical functional magnetic resonance imaging; 14. Reinforcement learning approaches to computational clinical neuroscience; Section IV. Developmental Psychopathology and Longitudinal Methods: 15. Studying psychopathology in early life: foundations of developmental psychopathology; 16. Adolescence and puberty: understanding the emergency of psychopathology; 17. Quantitative genetics research strategies for studying gene-environment interplay in the development of child and adolescent psychopathology; 18. Designing and managing longitudinal studies; 19. Measurement and comorbidity models for longitudinal data; Section V. Intervention Approaches: 20. The multiphase optimization strategy for developing and evaluating behavioral interventions; 21. Future directions in developing and evaluating psychological interventions; 22. Health psychology and behavioral medicine: methodological issues in the study of psychosocial influences on disease; Section VI. Intensive Longitudinal Designs: 23. Ambulatory assessment; 24. Modeling intensive longitudinal data; 25. Modeling the individual: bridging nomothetic and idiographic levels of analysis; 26. Social processes and dyadic designs; 27. Models for dyadic data; Section VII. General Analytic Considerations: 28. Reproducibility in clinical psychology; 29. Meta-analysis: integration of empirical findings through quantitative modeling; 30. Mediation, moderation, and conditional process analysis: regression-based approaches for clinical research; 31. Statistical inference for causal effects in clinical psychology: fundamental concepts and analytical approaches; 32. Analyzing nested data: multilevel modeling and alternative approaches; 33. Missing data analyses; 34. Machine learning for clinical psychology and clinical neuroscience.