New to this Second Edition are extensive updates to key chapters on the digestive system, heart, and breast, entirely new chapters on sentinel lymph nodes, transplantation, and preparation of tissues for molecular analysis to reflect emerging trends in surgical pathology practice. The authors have revised each chapter to conform to the recently published College of American Pathologists (CAP) and Association of Directors of Anatomic Pathologists (ADAP) guidelines.

I. General Approach and Techniques: 1. General Approach to Surgical Pathology Specimens, 2. Laboratory Techniques, 3. Preparation of Tissues for Molecular Analysis, 4. Photography. II. Lymph Nodes for Metastatic Tumors. 5. Lymph Nodes. III. The Head & Neck: 6. Larynx, 7. Salivary Glands, 8. Complex Specimens, 9. Craniofacial Bones, 10. Radical Neck Dissection. IV. The Digestive System: 11. Esophagus, 12. Stomach, 13. Non-neoplastic Intestinal Disease, 14. Neoplastic Instetinal Disease, 15. Appendix, 16. Liver, 17. Gallbladder, 18. Pancreas. V. The Cardiovascular/Respiratory System: 19. Heart, Heart Valves and Vessels, 20. Lungs, 21. Transplant Specimens. VI. Bone, Soft Tissue, and Skin: 22. Bone, 23. Soft Tissue, nerves, and Muscle, 24. Skin, 25. VII. Breast: 25. Breast. VIII. The Femal Genital System: 26. Vulva, 27. Uterus, Cervix, and Vagina. 28. Ovary and Fallopian Tube, 29. Products of Conception and Placentas. IX. The Urinary Tract and Male Genital System: 30. Penis, 31. Prostate, 32. Testis, 33. Kidney, 34. Bladder. X. The Ocular System: 35. Eye. XI. The Endocrine System: 36. Thyroid, 37. Parathyroid Glands, 38. Adrenal Glands. XII. Pediatric Tumors: 39. Pediatric Tumors. XIII. The Central Nervous System: 40. Brain and Spinal Cord. XIV. The Hemaopoietic and Lymphatic System: 41. Lymph Nodes, 42. Spleen, 43. Thymus, 44. Bone Marrow. XIV. Odds and Ends: 45. Common Uncomplicated Specimens.