ANITA THAPAR, MBBCh, PhD, FRCPsych, FMedSci, CBE, Professor of Child and Adolescent Psychiatry, Child and Adolescent Psychiatry Section, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK.

DANIEL S. PINE, MD, Chief, Section on Development and Affective Neuroscience, National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda, MD, USA.

SAMUELE CORTESE, MD, PhD, NIHR Research Professor and Professor of Child and Adolescent Psychiatry, University of Southampton, UK.

CATHY CRESWELL, BA (Ox Hons), DClinPsy, PhD, Professor of Developmental Clinical Psychology, Departments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.

TAMSIN J. FORD, PhD, FRCPsych, FMedSci, CBE, Professor of Child and Adolescent Psychiatry, Department of Psychiatry, University of Cambridge, Cambridge, UK.

JAMES F. LECKMAN, MD, PhD, Neison Harris Professor of Child Psychiatry, Child Study Center, Yale University, New Haven, CT, USA.

ARGYRIS STRINGARIS, MD, PhD, FRCPsych, Professor of Child and Adolescent Psychiatry, Faculty of Brain Sciences, University College London, London, UK.

List of Contributors viii

Foreword xiv

Preface xv

About the companion website xvi

Part I: Conceptual issues and research approaches

A: Developmental psychopathology

1 Development and psychopathology: a life course perspective 5
Stephan Collishaw and Frances Rice

2 Diagnosis, diagnostic formulation, and classification 19
Daniel S. Pine

3 Neurodevelopmental disorders 31
Anita Thapar and Francesca Happé

4 Conceptual issues and empirical challenges in relation to disruptive and challenging behavior 42
Essi Viding and Stephane De Brito

5 Emotion, emotion regulation and disorder: conceptual issues for clinicians and neuroscientists 55
Argyris Stringaris

6 Attachment: normal development, individual differences, and associations with experience 68
Kristin Bernard and Mary Dozier

7 Infant and early childhood mental health 81
Brittnie Fowler and Charles H. Zeanah

8 Temperament mechanisms in developmental psychopathology 94
Kristin A. Buss and Koraly Pérez-Edgar

9 Transdiagnostic perspectives 107
Giovanni Abrahão Salum and Mauricio Scopel Hoffmann

B: Neurobiology

10 Neurobiological perspectives on the developing human brain 123
Mark H. Johnson and Duncan E. Astle

11 Neuroimaging in child and adolescent psychiatry: the key elements 137
Tonya White

12 Systems neuroscience 151
Daniel S. Pine

C: Research approaches and service planning

13 Identifying causal effects using natural experiments and other designs 165
Anita Thapar and Kate Tilling

14 The role of epidemiology and youth voice in planning, organizing, and improving mental health services 178
Tamsin J. Ford and Tamsin Newlove-Delgado

15 Establishing the clinical effectiveness of interventions and implementations 191
Helena Chmura Kraemer

16 What clinicians need to know about statistical methods 203
Rachael Bedford and Daniel Stahl

17 How can economics help decision-makers to improve child and adolescent mental health equitably and efficiently? 218
Martin Knapp and Sara Evans-Lacko

18 Public health challenges in child and adolescent mental health: dealing with global and local threats 231
Lucie Cluver, Isang Awah and Andrea Danese

19 Legal issues in the care and treatment of children with mental health problems 242
Brenda Hale and Jonathan Herring Copyrighted Material

Part II: Influences on psychopathology

20 Biological mechanisms linking childhood adversity to mental health problems 255
Andrea Danese and Eamon McCrory

21 Genetics 268
Anita Thapar and Matthew W. State

22 Psychosocial adversity 283
Jennifer Jenkins, Sheri Madigan and Louise Arseneault

23 Resilience: a multilevel developmental psychopathology perspective 295
Dante Cicchetti

24 Impact of parental psychiatric disorder on children's psychological outcomes 307
Alan Stein, Rebecca M. Pearson and Gordon Harold

25 Child abuse and neglect 319
Danya Glaser

26 Neurological disorders and psychopathology 332
Isobel Heyman, David Skuse and Ashley Liew

Part III: Approaching the clinical encounter

A: The clinical assessment

27 Clinical assessment and formulation 349
James F. Leckman

28 Use of structured interviews, rating scales, and observational methods in clinical settings 361
Argyris Stringaris

29 Psychological assessment in the clinical context 374
William Mandy, Jennifer L. Hudson and Tara Murphy

30 Physical examination and medical investigation 386
Kenneth E. Towbin

B: Interventions

31 Psychological interventions: overview and critical issues for the field 401
V. Robin Weersing and Michelle Rozenman

32 Prevention of mental, emotional, and behavioral disorders and promotion of well-being 414
Nathaniel R. Riggs and Brittany Rhoades Cooper

33 Parenting programs 428
Stephen Scott and Frances Gardner

34 Cognitive and behavioral therapies for children and young people 441
Cathy Creswell and Eleanor Leigh

35 Systemic family therapy 453
Mark Rivett, Hannah Sherbersky and Rick Miller

36 Relationship-based treatments 465
Jonathan Green and Nick Midgley

37 Educational interventions for children's learning difficulties 477
Charles Hulme, Enrica Donolato and Monica Melby-Lervåg

38 School-based mental health interventions 490
Hiran Thabrew and Sally Merry

39 Pharmacological treatments, dietary-based interventions, and neuromodulation therapies 502
Samuele Cortese and David Coghill

C: Contexts of the clinical encounter and specific clinical situations

40 Diversity: gender identity and sexual orientation 519
Tomer Shechner and Aron Janssen

41 Refugee, asylum-seeking, and internally displaced children 532
Mina Fazel

42 Residential care, foster care, and adoption 547
Helen Minnis and Rachel Hiller

43 Pediatric consultation and psychiatric aspects of somatic disease 558
Eric P. Hazen and Jessica E. Becker

44 Children with specific sensory impairments 570
Naomi Dale and Fionna Bathgate

45 Child and youth mental health services in community health care settings 584
J.L. Henderson and Skye Barbic

46 Working in low-resource settings 593
Dan J. Stein and Lauren Franz

47 Forensic child and adolescent psychiatry 605
Alexandra Lewis, Seena Fazel and Rohan Borschmann

48 Intensive community services, day units, and inpatient services 619
Andy Cotgrove, Bernadka Dubicka and Gabrielle A. Carlson

49 Digital technology: assessment and treatment 633
Chris Hollis, Maria Loades and Charlotte L. Hall

Part IV: Clinical syndromes: neurodevelopment, emotional, behavior, somatic/body- brain

A: Neurodevelopment

50 Autism 651
Peter Szatmari, Stephanie H. Ameis and Meng-Chuan Lai

51 Developmental language disorders 674
Courtenay Norbury

52 Specific learning disorders 692
Margaret J. Snowling and Charles Hulme

53 Intellectual disability 712
Emily Simonoff and Maria Rogdaki

54 Attention deficit hyperactivity disorder 732
Samuele Cortese and Luis Augusto Rohde

55 Tic disorders 752
James F. Leckman and Michael H. Bloch

56 Schizophrenia and psychosis 771
Marinos Kyriakopoulos

B: Emotional

57 Disorders of attachment and social engagement related to deprivation 793
Julianna Finelli and Charles H. Zeanah

58 Post-traumatic stress disorder 807
Richard Meiser-Stedman, Patrick Smith and William Yule

59 Anxiety disorders 824
Daniel S. Pine

60 Obsessive- compulsive disorder 842
Philip Shaw and Judith L. Rapoport

61 Body dysmorphic disorder 860
Georgina Krebs and David Mataix-Cols

62 Bipolar disorder in childhood and adolescence 880
Daniel P. Dickstein and Danella M. Hafeman

63 Depressive disorders in children and adolescents 898
John T. Walkup and Jeffrey R. Strawn

64 Self-harm in young people 915
Dennis Ougrin and Michael Kaess

C: Behavior

65 Oppositional defiant and conduct disorders 937
Stephen Scott and Christian Bachmann

66 Substance use and substance use disorder 956
Eilish Gilvarry

67 Personality disorders 975
Jonathan Hill and Carla Sharp

D: Somatic/body- brain

68 Sleep and sleep disorders in children and adolescents 995
Eleanor L. McGlinchey and Judith A. Owens

69 Feeding and eating disorders 1016
Rachel Bryant-Waugh and Julian Baudinet

70 Somatic symptom and related disorders 1035
Charlotte Ulrikka Rask, Laura Markley and Eva Szigethy

Index 1054