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Robustness and Evolvability in Living Systems
Taschenbuch von Andreas Wagner
Sprache: Englisch

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Beschreibung
All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness.

Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness.

Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations.
All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness.

Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness.

Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations.
Über den Autor
Andreas Wagner
Details
Erscheinungsjahr: 2007
Fachbereich: Gentechnologie
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Seiten: 384
ISBN-13: 9780691134048
ISBN-10: 0691134049
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Wagner, Andreas
Hersteller: Princeton University Press
Maße: 234 x 156 x 21 mm
Von/Mit: Andreas Wagner
Erscheinungsdatum: 22.07.2007
Gewicht: 0,582 kg
preigu-id: 102043042
Über den Autor
Andreas Wagner
Details
Erscheinungsjahr: 2007
Fachbereich: Gentechnologie
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Seiten: 384
ISBN-13: 9780691134048
ISBN-10: 0691134049
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Wagner, Andreas
Hersteller: Princeton University Press
Maße: 234 x 156 x 21 mm
Von/Mit: Andreas Wagner
Erscheinungsdatum: 22.07.2007
Gewicht: 0,582 kg
preigu-id: 102043042
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