A comprehensive investigation into the regulation of Ca2+-ATPases, F-type ATPases, and V-type ATPases

Explores the specific inhibitors and molecular probes for membrane ATPases to improve the therapy of various diseases

An informative resource to improve diverse ATPase therapeutic approaches of life threatening diseases

Includes supplementary material: [...]

Part A.- 1 Historical Perspectives of Ca2+ ATPase.- 2 The Plasma Membrane Ca2+ATPases: Isoforms Specificity and


Functional Versatility.- 3 PMCA2 w/a Splice Variant: A Key Regulator of Hair Cell Mechanotransduction Machinery.-


4 PMCA-3, A Mysterious Isoform of Calcium Pump.- 5 The ATP2B Plasma Membrane Ca2+ ATPase Family: Regulation in


Response to Changing Demands of Cellular Calcium Transport.- 6 The Plasma Membrane Ca2+-ATPase and the Na/Ca


exchanger in ß-cell Function and Diabetes.- 7 Long-range Allosteric Regulation of Pumps and Transporters: What Can


We Learn From Mammalian NCX Antiporters?.- 8 Regulation of Ca2+/Mg2+ecto-ATPase in the Heart.- Part B.- 9 The


Ca2+-ATPase of the Sarco/endoplasmic Reticulum(SERCA):Structure and Control.- 10 Functional and Structural


Insights into Sarcolipin, a Regulator of the Sarco-Endoplasmic Reticulum Ca2+-ATPases.- 11 Regulation of Sarco


(endo)plasmic Reticulum Calcium ATPase (SERCA) in Response to Exercise.- 12 Calcium Handling in Pulmonary


Vasculature Under Oxidative Stress: Focus on SERCA.- 13 Plant Type 2B Ca2+-ATPases: The Diversity of Isoforms of


the Model PlantArabidopsis Thaliana.- 14 Regulation of Ca2+ transport ATPase by Amino-and Carboxy Terminal


Extensions: Mechanisms and (Patho)Physiological Implications.- Part A.- 15 Function and Regulation of Mammalian


V-ATPase Isoforms.- 16 Eucaryotic V-type ATPase and its Super Complexes: From Structure and Function to Disease


and Drug Targeting.- 17 Vacuolar ATPase in Physiology and Pathology: Roles in Neurobiology, Infectious Disease and


Cancer.- 18 Vacular H+-ATPase Signaling in Cancer.- 19 V-ATPases and their Implication in Oral Cancer.- 20 The


Vacular Proton ATPase (V-ATPase): Regulation and Therapeutic Targeting.- Part D.- 21 Thiol-related Regulation of


the Mitochondrial F1Fo-ATPase Activity.- 22 F1Fo-ATPase Functions Under Markedly Acidic Conditions in Bacteria.-


23 Tuning the ATPase Activity of Hsp 90.- 24 Role of ATPase in Disease Processes.- 25 Renal H+-ATPase Function,


Regulation, and Role in Distal Renal Tubular Acidosis.- 26 Plasma Membrane ATPase: Potential Target for Antifungal


Drug Therapy.- 27 The Yeast Ca2+-ATPases and Ca2+/H+ Exchangers of the Secretory Pathway and Their Regulation.- 28


Role of P5A-type ATPase in Ion Homeostasis and Signalling: Shedding Light on obscure Pump.