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Pharmaceutical Biotechnology
Fundamentals and Applications
Buch von Daan J. A. Crommelin (u. a.)
Sprache: Englisch

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Beschreibung

This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry. The Fifth Edition completely updates the previous edition, and also includes additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech and enzyme replacement therapy.

This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry. The Fifth Edition completely updates the previous edition, and also includes additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech and enzyme replacement therapy.

Inhaltsverzeichnis
Molecular Biotechnology.- Biophysical and biochemical analysis of recombinant proteins.- Production and downstream processing of biotech products.- Formulation of biotech products, including biopharmaceutical considerations.- Pharmacokinetics and pharmacodynamics of peptide and protein drugs.- Immunogenicity of pharmaceutical proteins.- General considerations of monoclonal antibodies from structure to therapeutic application.- Genomics, Other "Omics" Technologies, Personalized Medicine and Additional Biotechnology-Related Techniques.- Dispensing biotechnology products: handling, professional education and product information.- Economic considerations in medical biotechnology.- Regulatory framework for biosimilars.- Vaccines.- Oligonucleotides and siRNA.- Gene therapy.- Stem cell technology.- Therapeutic Applications.-Endocrinology.- Insulin.- Follicle-stimulating hormone.- Growth hormone.- Cardiovascular and Respiratory Applications.- Recombinant coagulation factors and thrombolytics.- Recombinant human deoxyribonuclease.- Oncology.- Monoclonal antibodies in oncology .- Hematopoetic growth factors.- Inflammation and Immunemodulation.- Monoclonal antibodies in transplantation.- Monoclonal antibodies and antibody-based therapeutics in anti-inflammatory therapy.- Interferons and interleukins.- Anti-infectious diseases.- Monoclonal antibodies.- Enzyme replacement therapy.
Details
Fachbereich: Chemische Technik
Genre: Technik
Rubrik: Naturwissenschaften & Technik
Medium: Buch
ISBN-13: 9783030007096
ISBN-10: 303000709X
Sprache: Englisch
Herstellernummer: 978-3-030-00709-6
Redaktion: Crommelin, Daan J. A.
Sindelar, Robert D.
Meibohm, Bernd
Auflage: 5. Aufl.
Hersteller: Springer
Springer, Berlin
Springer International Publishing
Abbildungen: XXIII, 653 p. 246 illus., 227 illus. in color. With 5th edition.
Maße: 284 x 216 x 44 mm
Von/Mit: Daan J. A. Crommelin (u. a.)
Erscheinungsdatum: 30.04.2019
Gewicht: 1,86 kg
Artikel-ID: 114177722
Inhaltsverzeichnis
Molecular Biotechnology.- Biophysical and biochemical analysis of recombinant proteins.- Production and downstream processing of biotech products.- Formulation of biotech products, including biopharmaceutical considerations.- Pharmacokinetics and pharmacodynamics of peptide and protein drugs.- Immunogenicity of pharmaceutical proteins.- General considerations of monoclonal antibodies from structure to therapeutic application.- Genomics, Other "Omics" Technologies, Personalized Medicine and Additional Biotechnology-Related Techniques.- Dispensing biotechnology products: handling, professional education and product information.- Economic considerations in medical biotechnology.- Regulatory framework for biosimilars.- Vaccines.- Oligonucleotides and siRNA.- Gene therapy.- Stem cell technology.- Therapeutic Applications.-Endocrinology.- Insulin.- Follicle-stimulating hormone.- Growth hormone.- Cardiovascular and Respiratory Applications.- Recombinant coagulation factors and thrombolytics.- Recombinant human deoxyribonuclease.- Oncology.- Monoclonal antibodies in oncology .- Hematopoetic growth factors.- Inflammation and Immunemodulation.- Monoclonal antibodies in transplantation.- Monoclonal antibodies and antibody-based therapeutics in anti-inflammatory therapy.- Interferons and interleukins.- Anti-infectious diseases.- Monoclonal antibodies.- Enzyme replacement therapy.
Details
Fachbereich: Chemische Technik
Genre: Technik
Rubrik: Naturwissenschaften & Technik
Medium: Buch
ISBN-13: 9783030007096
ISBN-10: 303000709X
Sprache: Englisch
Herstellernummer: 978-3-030-00709-6
Redaktion: Crommelin, Daan J. A.
Sindelar, Robert D.
Meibohm, Bernd
Auflage: 5. Aufl.
Hersteller: Springer
Springer, Berlin
Springer International Publishing
Abbildungen: XXIII, 653 p. 246 illus., 227 illus. in color. With 5th edition.
Maße: 284 x 216 x 44 mm
Von/Mit: Daan J. A. Crommelin (u. a.)
Erscheinungsdatum: 30.04.2019
Gewicht: 1,86 kg
Artikel-ID: 114177722
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