Zu den bekanntesten Werken gehören das Pythagoras-Museum, die Neue Galleria Sabauda in Turin, der Wohnkomplex Milanofiori, das Kinderkrankenhaus in Parma, das Galliera-Krankenhaus in Genua, der Lido von Genua, das Ex Cinema Roma, die Triennale di Milano Terrace, der Lehariya Cluster in Jaipur, der Jafza Traders Market in Dubai und der Mehrzweckkomplex Ahmad Qasir in Teheran.

Die Projekte von OBR wurden auf der Architekturbiennale von Venedig, dem Royal Institute of British Architects in London, der Bienal de Arquitetura in Brasilia, dem MAXXI in Rom und der Triennale di Milano vorgestellt.

OBR wurde mit dem AR Award for Emerging Architecture der RIBA, dem Plusform under 40, dem Urbanpromo auf der 11° Biennale di Venezia, der ehrenvollen Erwähnung für die Medaglia d'Oro all'Architettura Italiana, dem Europe 40 Under 40 in Madrid, dem Leaf Award Gesamtsieger in London, dem WAN Residential Award, dem Building Healthcare Award, dem Inarch Award for Italian Architecture und dem American Architecture Prize in New York ausgezeichnet.

Paolo Brescia and Tommaso Principi, architects and founding partners of OBR Open Building Research, Milan

Among the best-known works: Pythagoras Museum, the New Galleria Sabauda in Turin, the Milanofiori Residential Complex, the Children Hospital in Parma, the Galliera Hospital in Genoa, the Lido of Genoa, the Ex Cinema Roma, the Triennale di Milano Terrace, Lehariya Cluster in Jaipur, the Jafza Traders Market in Dubai and the Multiuse Complex Ahmad Qasir in Teheran.

OBR´s projects have been featured in Venice Biennale of Architecture, Royal Institute of British Architects in London, Bienal de Arquitetura of Brasilia, MAXXI in Rome and Triennale di Milano.

OBR has been awarded the AR Award for Emerging Architecture at RIBA, the Plusform under 40, the Urbanpromo at the 11° Biennale di Venezia, the honourable mention for the Medaglia d´Oro all´Architettura Italiana, the Europe 40 Under 40 in Madrid, the Leaf Award overall winner in London, the WAN Residential Award, the Building Healthcare Award, the Inarch Award for Italian Architecture and the American Architecture Prize in New York.