Professor Helen M. Roche, Vice-President for Research, Innovation and Impact at University College Dublin, Ireland.

Professor Ian A. Macdonald, Professor Emeritus in Metabolic Physiology at the University of Nottingham, UK.

Professor Annemie M.W.J. Schols, Professor of Nutrition and Metabolism in Chronic Diseases at Maastricht University, the Netherlands.

Professor Susan A. Lanham-New, Professor of Human Nutrition and Head of Department at the University of Surrey, UK.

Contributors vii

Series Foreword ix

Series Editor's Preface x

About the Companion Website xii

1 Core Concepts of Nutrition 1
Ian A. Macdonald and Annemie M.W.J. Schols

2 Molecular Aspects of Nutrition 7
Herman E. Popeijus, Helen M. Roche, and Ronald P. Mensink

3 Integration of Metabolism 1: Energy 36
Jennifer L. Miles-Chan

4 Integration of Metabolism 2: Macronutrients 51
Abayomi O. Akanji and Keith N. Frayn

5 Integration of Metabolism 3: Protein and Amino Acids 76
Emily J. Ferguson, Nicholas A. Burd, Tyler A. Churchward-Venne, and Chris McGlory

6 Pregnancy and Lactation 93
Sharleen L. O'Reilly and Michelle K. McGuire

7 Growth and Ageing 110
Mark L. Wahlqvist

8 Nutrition, the Brain and the Gut Microbiota 161
Harriët Schellekens, Mara Loana Lesanu, and Siobhain M. O'Mahony

9 The Sensory Systems and Food Palatability 188
Connor M. Delahunty and Remco C. Havermans

10 The Gastrointestinal Tract 209
Mariano Mañas, Emilio Martínez de Victoria, Ángel Gil, María D. Yago, and John C. Mathers

11 The Cardiovascular System 255
Wendy L. Hall, Jayne V. Woodside, and J.A. Lovegrove

12 The Skeletal System 276
John M. Pettifor, Ann Prentice, Kate A. Ward, and Ansuyah Magan

13 The Immune and Inflammatory Systems 329
Parveen Yaqoob and Philip C. Calder

14 Phytochemicals 356
Gary Williamson and Jeremy P.E. Spencer

15 The Control of Food Intake 369
Graham Finlayson and Mark Hopkins

16 Overnutrition 378
Albert Flynn

17 Obesity 387
Gijs H. Goossens and Ellen E. Blaak

18 Undernutrition 403
Phoebe Hodges and Paul Kelly

19 Exercise Performance 414
Asker E. Jeukendrup and Louise M. Burke

About the Editors 449

Index 452