Nadine Attal, MD, PhD, is a neurologist, Professor of Therapeutics and Pain Medicine at Paris Saclay University, head of The Pain Center at Hôpital Ambroise Paré, Boulogne-Billancourt, France and associate director of the U 987 INSERM research Unit. She has played a leading role in translational research in pain and has published in leading journals. She is section editor for BJA and PainReports and Councilmember of the International Association for the Study of Pain. She was appointed "chevalier de la létion d'honneur" in 2016, and received awards from the French Science Academy (2017) and the Rynd Award from the Irish Society of Anesthesiologists (2022).

Dr. Didier Bouhassira (MD, PhD) has been trained in neurology and neurophysiology in Paris. He has been involved in both basic and clinical research on pain and is currently Director of Research at the National Institut for Health and Medical Research (Inserm). He is associate attending neurologist in the Pain Clinic at Ambroise Paré hospital in Boulogne-Billancourt and director of the laboratory of "Pathophysiology and Clinical Pharmacology of Pain" (Inserm U-987). Didier Bouhassira was president of the French Pain Society (2013-2016) and is an active member of several international associations or societies. He has been field editor for the European Journal of Pain (2008-2021) and associate editor for several scientific journals including Pain. He has co-authored over 220 articles in peer reviewed journals and has written a number of book chapters devoted to the pharmacology and pathophysiology of pain.

• SECTION I: CLINICAL CASES, DIAGNOSIS AND MANAGEMENT


• 1. Is this neuropathic pain?


• 2. How do I implement therapeutic management?


• 3. Back and leg pain


• 4. Paresthesia of the hand


• 5. Itch and herpes zoster


• 6. Painful legs and diabetes, case 1


• 7. Painful legs and diabetes, case 2


• 8. Groin pain after hernia repair


• 9. Pain after surgery for hand fracture


• 10. Pain and amputation


• 11. Pain and breast cancer surgery


• 12. Cold evoked symptoms after chemotherapy


• 13. Cervicobrachial pain and cancer


• 14. My body is boiling


• 15. Pain and Covid 19


• 16. Pelvic pain


• 17. Burning mouth


• 18. Orofacial pain


• 19. A lightning in the face


• 20. Brachial plexus avulsion


• 21. Pain and paraplegia l


• 22. Pain and multiple sclerosis


• 23. Sudden onset facial pain


• 24. Pain and Parkinson


• 25. Burning hands


• 26. Neuropathic pain in a child


• SECTION II: THERAPEUTIC OPTIONS IN PRIMARY CARE


• 27. Antidepressants and antiepileptics


• 28. Topical therapy


• 29. The case of opioids


• 30. Physical therapy


• 31. Psychotherapies


• 32. Complementary medicine


• 33. Transcutaneous electrical nerve stimulation


• SECTION III: SPECIALIZED ASSESSMENT AND THERAPY


• 34. Management of high risk patients


• 35. Management of patients with comorbididies


• 36. Management of neuropathic pain: role of patient reported outcome measures


• 37. Management of neuropathic pain: role of quantitative sensory testing


• 38. Complementary investigations


• 39. The case of cannabinoids


• 40. Nerve blocks and drug infusions


• 41. Noninvasive brain stimulation


• 42. When do I refer for invasive therapies?


• 43. Peripheral nerve stimulation and radiofrequency


• 44. Spinal cord stimulation


• 45. Invasive brain stimulation and intrathecal therapy