Multiparticulate Drug Delivery | Buch

Cover: 9781493970100 | Multiparticulate Drug Delivery | Ali R. Rajabi-Siahboomi | Buch | xii

Dekorationsartikel gehören nicht zum Leistungsumfang.

Sprache: Englisch

192,59 €*

inkl. MwSt.

Versandkostenfrei per Post / DHL

Aktuell nicht verfügbar

Kategorien:

Der Artikel ist nicht in deutscher Sprache verfasst.
Die Sprache der Produktbeschreibung und Details kann in Englisch angegeben sein. Sollten Sie Verständnisprobleme haben, wenden Sie sich gerne an uns.

Beschreibung

Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

Über den Autor

Ali Rajabi-Siahboomi is Vice President and Chief Scientific Officer at Colorcon Inc. He obtained his PhD in Pharmacy from University of Nottingham (UK). Dr. Rajabi-Siahboomi held various academic positions in Nottingham and Liverpool JM Universities (UK), before joining Colorcon. His main research interests are in the area of solid dosage form pharmaceutics and pharmaceutical technology with emphasis on oral drug delivery systems. He has published over 150 articles, book chapters, abstracts and patents.

Zusammenfassung

Comprehensive update on new and emerging approaches in the design of multiparticulate dosage forms

Covers the opportunities and hidden challenges that arise during formulation

Scale-up and manufacture Features case studies illustrating best practices

Includes supplementary material: [...]

Inhaltsverzeichnis

Overview of multiparticulates.- Characterization of inert pellets for drug layering.- The science and practice of extrusion-spheronization.- Fluid bed technology, process robustness and scale-up.- Solution and suspension drug layering on inert pellets.- Dry powder layering on pellets Mini-tabs; versatile multiparticulate options for oral drug delivery.- Science and practice of microencapsulation technology.- Use of multiparticulate systems for fixed dose combination drug delivery.- Dissolution testing consideration of multiparticulate system.- Taste masking of multiparticulate systems.- Multiparticulate systems for pediatrics.- Application of methacrylic acid copolymers polymers for oral multiparticulate drug delivery.- Ethylcellulose applications on multiparticulate dosage forms.- Multi-unit particulate systems (MUPS).- In-line particle size characterization of multipartuclate systems.- In-vivo characterization of multiparticulatesystems.

Details

Erscheinungsjahr:	2017
Fachbereich:	Chemische Technik
Genre:	Technik
Rubrik:	Naturwissenschaften & Technik
Medium:	Buch
Reihe:	Advances in Delivery Science and Technology
Inhalt:	xii 396 S. 56 s/w Illustr. 100 farbige Illustr. 396 p. 156 illus. 100 illus. in color.
ISBN-13:	9781493970100
ISBN-10:	1493970100
Sprache:	Englisch
Ausstattung / Beilage:	HC runder Rücken kaschiert
Einband:	Gebunden
Redaktion:	Rajabi-Siahboomi, Ali R.
Herausgeber:	Ali R Rajabi-Siahboomi
Auflage:	1st ed. 2017
Hersteller:	Springer New York Springer US, New York, N.Y. Advances in Delivery Science and Technology
Maße:	241 x 160 x 28 mm
Von/Mit:	Ali R. Rajabi-Siahboomi
Erscheinungsdatum:	28.05.2017
Gewicht:	0,776 kg

Artikel-ID: 109287718