Recently, monitoring of cerebral blood flow and cerebral oxygenation, both regionally and globally, has become feasible. Methods like thermodiffusion techniques, measurements of tissue pO2, laser-doppler-spectroscopy, near infrared spectroscopy and monitoring of oxygen saturation in the jugular bulb have successfully been used. This book discusses indications and results of CBF and cerebral oxygenation monitoring in critically ill patients.

Physiology and Pathophysiology of Cerebral Blood Flow and Metabolism.- Regulation of Cerebral Blood Flow - A Brief Review.- Relationship of Cerebral Blood Flow Disturbances with Brain Oedema Formation.- Measurement of Vascular Reactivity in Head Injured Patients.- Intermittent Measurements of Cerebral Blood Flow and Metabolism in Intensive Care.- Measurements of Cerebral Blood Flow and Metabolism in Severe Head Injury Using the Kety-Schmidt-Technique.- Xenon 133 - CBF Measurements in Severe Head Injury and Subarachnoid Haemorrhage.- Evaluation of Regional Cerebral Blood Flow in Acute Head Injury by Stable Xenon-Enhanced Computerized Tomography.- Continuous Monitoring of Cerebral Blood Flow and Metabolism in Intensive Care.- Thermodiffusion.- Cerebral Blood Flow (CBF) Monitoring in Intensive Care by Thermal Diffusion.- Monitoring of Regional Cerebral Blood Flow (CBF) in Acute Head Injury by Thermal Diffusion.- Tissue pO2.- Monitoring Cerebral Oxygenation: Experimental Studies and Preliminary Clinical Results of Continuous Monitoring of Cerebrospinal Fluid and Brain Tissue Oxygen Tension.- Studies of Tissue PO2 in Normal and Pathological Human Brain Cortex.- Laser-Doppler Flowmetry.- Applicability of Laser-Doppler Flowmetry for Cerebral Blood Flow Monitoring in Neurological Intensive Care.- Assessment of Cerebral Haemodynamics in Comatose Patients by Laser-Doppler Flowmetry - Preliminary Observations.- Near Infrared Spectroscopy.- Measurement of Adult Cerebral Haemodynamics Using Near Infrared Spectroscopy.- Transcranial Doppler Sonography.- Transcranial Doppler-Sonography in Severe Head Injury.- Jugular-Venous Oximetry.- Cerebral Oxygenation. Monitoring and Management.- Technical Considerations in Continuous Jugular Venous Oxygen Saturation Measurement.-Desaturation Episodes after Severe Head Injury: Influence on Outcome.- Monitoring of Jugular Oxygen Saturation in Comatose Patients with Subarachnoid Haemorrhage and Intracerebral Haematomas.- Influence of Body Position on Jugular Venous Oxygen Saturation, Intracranial Pressure and Cerebral Perfusion Pressure.- Continuous Monitoring of Jugular Bulb Oxygen Saturation and the Effect of Drugs Acting on Cerebral Metabolism.- Consequences for Clinical Management.- Early and Late Systemic Hypotension as a Frequent and Fundamental Source of Cerebral Ischemia Following Severe Brain Injury in the Traumatic Coma Data Bank.