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Molecular Evolution and Phylogenetics
Taschenbuch von Masatoshi Nei (u. a.)
Sprache: Englisch

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Beschreibung
During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis
of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth.
Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees,
statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical
examples using the computer program MEGA2 that is provided.
During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis
of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth.
Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees,
statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical
examples using the computer program MEGA2 that is provided.
Inhaltsverzeichnis
  • 1: Molecular basis of evolution

  • 2: Evolutionary changes of amino acid sequences

  • 3: Evolutionary changes of DNA sequences

  • 4: Synonymous and nonsynonymous nucleotide substitutions

  • 5: Phylogenetic trees

  • 6: Phylogenetic inference: Distance methods

  • 7: Phylogenetic inference: Maximum parsimony methods

  • 8: Phylogenetic inference: Maximum likelihood methods

  • 9: Accuracies and statistical tests of phylogenetic trees

  • 10: Molecular clocks and linearized trees

  • 11: Ancestral nucleotide and amino acid sequences

  • 12: Genetic polymorphism and evolution

  • 13: Population trees from genetic markers

  • 14: Perspectives

  • Appendices

  • A. Mathematical sumbols and notations

  • B. Geological timescale

  • C. Geological events in the Cenozoic and Meszoic eras

  • D. Evolution of organisms based on the fossil record

Details
Erscheinungsjahr: 2000
Genre: Technik allg.
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
ISBN-13: 9780195135855
ISBN-10: 0195135857
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Nei, Masatoshi
Kumar, Sudhir
Hersteller: Oxford University Press, USA
Maße: 254 x 178 x 19 mm
Von/Mit: Masatoshi Nei (u. a.)
Erscheinungsdatum: 01.01.2000
Gewicht: 0,663 kg
Artikel-ID: 130036828
Inhaltsverzeichnis
  • 1: Molecular basis of evolution

  • 2: Evolutionary changes of amino acid sequences

  • 3: Evolutionary changes of DNA sequences

  • 4: Synonymous and nonsynonymous nucleotide substitutions

  • 5: Phylogenetic trees

  • 6: Phylogenetic inference: Distance methods

  • 7: Phylogenetic inference: Maximum parsimony methods

  • 8: Phylogenetic inference: Maximum likelihood methods

  • 9: Accuracies and statistical tests of phylogenetic trees

  • 10: Molecular clocks and linearized trees

  • 11: Ancestral nucleotide and amino acid sequences

  • 12: Genetic polymorphism and evolution

  • 13: Population trees from genetic markers

  • 14: Perspectives

  • Appendices

  • A. Mathematical sumbols and notations

  • B. Geological timescale

  • C. Geological events in the Cenozoic and Meszoic eras

  • D. Evolution of organisms based on the fossil record

Details
Erscheinungsjahr: 2000
Genre: Technik allg.
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
ISBN-13: 9780195135855
ISBN-10: 0195135857
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Nei, Masatoshi
Kumar, Sudhir
Hersteller: Oxford University Press, USA
Maße: 254 x 178 x 19 mm
Von/Mit: Masatoshi Nei (u. a.)
Erscheinungsdatum: 01.01.2000
Gewicht: 0,663 kg
Artikel-ID: 130036828
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