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of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth.
Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees,
statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical
examples using the computer program MEGA2 that is provided.
of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth.
Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees,
statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical
examples using the computer program MEGA2 that is provided.
- 1: Molecular basis of evolution
- 2: Evolutionary changes of amino acid sequences
- 3: Evolutionary changes of DNA sequences
- 4: Synonymous and nonsynonymous nucleotide substitutions
- 5: Phylogenetic trees
- 6: Phylogenetic inference: Distance methods
- 7: Phylogenetic inference: Maximum parsimony methods
- 8: Phylogenetic inference: Maximum likelihood methods
- 9: Accuracies and statistical tests of phylogenetic trees
- 10: Molecular clocks and linearized trees
- 11: Ancestral nucleotide and amino acid sequences
- 12: Genetic polymorphism and evolution
- 13: Population trees from genetic markers
- 14: Perspectives
- Appendices
- A. Mathematical sumbols and notations
- B. Geological timescale
- C. Geological events in the Cenozoic and Meszoic eras
- D. Evolution of organisms based on the fossil record
| Erscheinungsjahr: | 2000 |
|---|---|
| Genre: | Technik allg. |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Taschenbuch |
| ISBN-13: | 9780195135855 |
| ISBN-10: | 0195135857 |
| Sprache: | Englisch |
| Ausstattung / Beilage: | Paperback |
| Einband: | Kartoniert / Broschiert |
| Autor: |
Nei, Masatoshi
Kumar, Sudhir |
| Hersteller: | Oxford University Press, USA |
| Maße: | 254 x 178 x 19 mm |
| Von/Mit: | Masatoshi Nei (u. a.) |
| Erscheinungsdatum: | 01.01.2000 |
| Gewicht: | 0,663 kg |
- 1: Molecular basis of evolution
- 2: Evolutionary changes of amino acid sequences
- 3: Evolutionary changes of DNA sequences
- 4: Synonymous and nonsynonymous nucleotide substitutions
- 5: Phylogenetic trees
- 6: Phylogenetic inference: Distance methods
- 7: Phylogenetic inference: Maximum parsimony methods
- 8: Phylogenetic inference: Maximum likelihood methods
- 9: Accuracies and statistical tests of phylogenetic trees
- 10: Molecular clocks and linearized trees
- 11: Ancestral nucleotide and amino acid sequences
- 12: Genetic polymorphism and evolution
- 13: Population trees from genetic markers
- 14: Perspectives
- Appendices
- A. Mathematical sumbols and notations
- B. Geological timescale
- C. Geological events in the Cenozoic and Meszoic eras
- D. Evolution of organisms based on the fossil record
| Erscheinungsjahr: | 2000 |
|---|---|
| Genre: | Technik allg. |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Taschenbuch |
| ISBN-13: | 9780195135855 |
| ISBN-10: | 0195135857 |
| Sprache: | Englisch |
| Ausstattung / Beilage: | Paperback |
| Einband: | Kartoniert / Broschiert |
| Autor: |
Nei, Masatoshi
Kumar, Sudhir |
| Hersteller: | Oxford University Press, USA |
| Maße: | 254 x 178 x 19 mm |
| Von/Mit: | Masatoshi Nei (u. a.) |
| Erscheinungsdatum: | 01.01.2000 |
| Gewicht: | 0,663 kg |
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