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Stella Pelengaris Ph.D is Director of Pharmalogos and previous Researcher at the Imperial Cancer Research Fund, and Senior Research Fellow at the University of Warwick and Warwick Medical School.
Mike Khan Ph.D FRCP is Associate Professor of Medicine at University Hospitals of Coventry and Warwickshire and previous Head of Molecular Medicine at the University of Warwick.
Preface to the Second Edition, ix
Reviews of the First Edition, x
Acknowledgments and Dedication, xi
About the Companion Website, xii
Introduction, 1
1 Overview of Cancer Biology, 3
Michael Khan and Stella Pelengaris
2 The Burden of Cancer, 43
William P. Steward and Anne L. Thomas
3 Nature and Nurture in Oncogenesis, 67
Michael Khan and Stella Pelengaris
4 DNA Replication and the Cell Cycle, 111
Stella Pelengaris and Michael Khan
5 Growth Signaling Pathways and the New Era of Targeted Treatment of Cancer, 146
Stella Pelengaris and Michael Khan
6 Oncogenes, 188
Stella Pelengaris and Michael Khan
7 Tumor Suppressors, 239
Martine F. Roussel
8 Cell Death, 266
Stella Pelengaris and Michael Khan
9 Senescence, Telomeres, and Cancer Stem Cells, 295
Maria A. Blasco and Michael Khan
10 Genetic Instability, Chromosomes, and Repair, 314
Michael Khan
11 There Is More to Cancer than Genetics: Regulation of Gene and Protein Expression by Epigenetic Factors, Small Regulatory RNAs, and Protein Stability, 350
Stella Pelengaris and Michael Khan
12 Cell Adhesion in Cancer, 383
Charles H. Streuli
13 Tumor Immunity and Immunotherapy, 410
Cassian Yee
14 Tumor Angiogenesis, 429
Christiana Ruhrberg
15 Cancer Chemistry: Designing New Drugs for Cancer Treatment, 438
Ana M. Pizarro and Peter J. Sadler
16 Biologically Targeted Agents from Bench to Bedside, 461
Michael Khan, Peter Sadler, Ana M. Pizarro, and Stella Pelengaris
17 The Diagnosis of Cancer, 509
Anne L. Thomas, Bruno Morgan, and William P. Steward
18 Treatment of Cancer: Chemotherapy and Radiotherapy, 526
Anne L. Thomas, J.P. Sage, and William P. Steward
19 Caring for the Cancer Patient, 544
Nicky Rudd and Esther Waterhouse
20 Systems Biology of Cancer, 554
Walter Schubert, Norbert C.J. de Wit, and Peter Walden
Glossary, 585
Answers to Questions, 597
Index, 603
| Erscheinungsjahr: | 2013 |
|---|---|
| Fachbereich: | Allgemeines |
| Genre: | Biologie |
| Rubrik: | Naturwissenschaften & Technik |
| Thema: | Lexika |
| Medium: | Taschenbuch |
| Seiten: | 640 |
| Inhalt: | 640 S. |
| ISBN-13: | 9781118008812 |
| ISBN-10: | 1118008812 |
| Sprache: | Englisch |
| Herstellernummer: | 1W118008810 |
| Einband: | Kartoniert / Broschiert |
| Redaktion: |
Pelengaris, Stella
Khan, Michael |
| Herausgeber: | Stella Pelengaris/Mike Khan |
| Auflage: | 2nd edition |
| Hersteller: |
Wiley
John Wiley & Sons |
| Maße: | 280 x 216 x 34 mm |
| Von/Mit: | Stella Pelengaris (u. a.) |
| Erscheinungsdatum: | 28.05.2013 |
| Gewicht: | 1,57 kg |
Stella Pelengaris Ph.D is Director of Pharmalogos and previous Researcher at the Imperial Cancer Research Fund, and Senior Research Fellow at the University of Warwick and Warwick Medical School.
Mike Khan Ph.D FRCP is Associate Professor of Medicine at University Hospitals of Coventry and Warwickshire and previous Head of Molecular Medicine at the University of Warwick.
Preface to the Second Edition, ix
Reviews of the First Edition, x
Acknowledgments and Dedication, xi
About the Companion Website, xii
Introduction, 1
1 Overview of Cancer Biology, 3
Michael Khan and Stella Pelengaris
2 The Burden of Cancer, 43
William P. Steward and Anne L. Thomas
3 Nature and Nurture in Oncogenesis, 67
Michael Khan and Stella Pelengaris
4 DNA Replication and the Cell Cycle, 111
Stella Pelengaris and Michael Khan
5 Growth Signaling Pathways and the New Era of Targeted Treatment of Cancer, 146
Stella Pelengaris and Michael Khan
6 Oncogenes, 188
Stella Pelengaris and Michael Khan
7 Tumor Suppressors, 239
Martine F. Roussel
8 Cell Death, 266
Stella Pelengaris and Michael Khan
9 Senescence, Telomeres, and Cancer Stem Cells, 295
Maria A. Blasco and Michael Khan
10 Genetic Instability, Chromosomes, and Repair, 314
Michael Khan
11 There Is More to Cancer than Genetics: Regulation of Gene and Protein Expression by Epigenetic Factors, Small Regulatory RNAs, and Protein Stability, 350
Stella Pelengaris and Michael Khan
12 Cell Adhesion in Cancer, 383
Charles H. Streuli
13 Tumor Immunity and Immunotherapy, 410
Cassian Yee
14 Tumor Angiogenesis, 429
Christiana Ruhrberg
15 Cancer Chemistry: Designing New Drugs for Cancer Treatment, 438
Ana M. Pizarro and Peter J. Sadler
16 Biologically Targeted Agents from Bench to Bedside, 461
Michael Khan, Peter Sadler, Ana M. Pizarro, and Stella Pelengaris
17 The Diagnosis of Cancer, 509
Anne L. Thomas, Bruno Morgan, and William P. Steward
18 Treatment of Cancer: Chemotherapy and Radiotherapy, 526
Anne L. Thomas, J.P. Sage, and William P. Steward
19 Caring for the Cancer Patient, 544
Nicky Rudd and Esther Waterhouse
20 Systems Biology of Cancer, 554
Walter Schubert, Norbert C.J. de Wit, and Peter Walden
Glossary, 585
Answers to Questions, 597
Index, 603
| Erscheinungsjahr: | 2013 |
|---|---|
| Fachbereich: | Allgemeines |
| Genre: | Biologie |
| Rubrik: | Naturwissenschaften & Technik |
| Thema: | Lexika |
| Medium: | Taschenbuch |
| Seiten: | 640 |
| Inhalt: | 640 S. |
| ISBN-13: | 9781118008812 |
| ISBN-10: | 1118008812 |
| Sprache: | Englisch |
| Herstellernummer: | 1W118008810 |
| Einband: | Kartoniert / Broschiert |
| Redaktion: |
Pelengaris, Stella
Khan, Michael |
| Herausgeber: | Stella Pelengaris/Mike Khan |
| Auflage: | 2nd edition |
| Hersteller: |
Wiley
John Wiley & Sons |
| Maße: | 280 x 216 x 34 mm |
| Von/Mit: | Stella Pelengaris (u. a.) |
| Erscheinungsdatum: | 28.05.2013 |
| Gewicht: | 1,57 kg |
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