John E. Bennett, MD, Adjunct Professor of Medicine, Uniformed Services University of the Health Sciences, F. Edward Hebert School of Medicine; Bethesda, Maryland

I Basic Principles in the Diagnosis and Management of Infectious Diseases
A MICROBIAL PATHOGENESIS
1 A Molecular Perspective of Microbial Pathogenicity
2 The Human Microbiome of Local Body Sites and Their Unique Biology
3 Prebiotics, Probiotics, and Synbiotics
B HOST DEFENSE MECHANISMS
4 Innate (General or Nonspecific) Host Defense Mechanisms
5 Adaptive Immunity: Antibodies and Immunodeficiencies
6 Cell-Mediated Defense Against Infection
7 Mucosal Immunity
8 Granulocytic Phagocytes
9 Complement and Deficiencies
10 Human Genetics and Infection
11 Nutrition, Immunity, and Infection
12 Evaluation of the Patient With Suspected Immunodeficiency
C EPIDEMIOLOGY OF INFECTIOUS DISEASE
13 Applied Epidemiology for the Infectious Diseases Physician
14 Emerging and Reemerging Infectious Disease Threats
15 Bioterrorism: An Overview
D CLINICAL MICROBIOLOGY
16 The Clinician and the Microbiology Laboratory: Test Ordering, Specimen Collection, and Result Interpretation
E ANTIINFECTIVE THERAPY
17 Principles of Antiinfective Therapy
18 Molecular Mechanisms of Antibiotic Resistance in Bacteria
19 Pharmacokinetics and Pharmacodynamics of Antiinfective Agents
20 Penicillins and ß-Lactamase Inhibitors
21 Cephalosporins
22 Ertapenem, Imipenem, Meropenem, Doripenem, and Aztreonam
23 Antibiotic Allergy
24 Fusidic Acid
25 Aminoglycosides
26 Tetracyclines, Glycylcyclines, and Chloramphenicol
27 Rifamycins
28 Metronidazole
29 Macrolides and Clindamycin
30 Glycopeptides (Vancomycin and Teicoplanin) and Lipoglycopeptides (Telavancin, Oritavancin, and Dalbavancin)
31 Daptomycin and Quinupristin-Dalfopristin
32 Polymyxins (Polymyxin B and Colistin)
33 Linezolid, Tedizolid, and Other Oxazolidinones
34 Sulfonamides and Trimethoprim; Trimethoprim-Sulfamethoxazole
35 Quinolones
36 Unique Antibacterial Agents
37 Urinary Tract Agents: Nitrofurantoin, Fosfomycin, and Methenamine
38 Topical Antibacterials
39 Antimycobacterial Agents
40A Antifungal Agents: Amphotericin B
40B Antifungal Drugs: Azoles
40C Antifungal Drugs: Echinocandins
40D Antifungal Drugs: Flucytosine
41 Antimalarial Drugs
42 Drugs for Protozoal Infections Other Than Malaria
43 Drugs for Helminths
44 Antiviral Agents: General Principles
45 Antiviral Drugs for Influenza and Other Respiratory Virus Infections
46 Antivirals Against Herpesviruses
47 Antiviral Drugs Against Hepatitis Viruses
48 Miscellaneous Antiviral Agents (Interferons, Tecovirimat, Imiquimod, Pocapavir, Pleconaril)
49 Immunomodulators
50 Hyperbaric Oxygen
51 Antimicrobial Stewardship
52 Designing and Interpreting Clinical Studies in Infectious Diseases
53 Outpatient Parenteral Antimicrobial Therapy
54 Tables of Antiinfective Agent Pharmacology
II Major Clinical SyndromesA FEVER
55 Temperature Regulation and the Pathogenesis of Fever
56 Fever of Unknown Origin
57 The Acutely Ill Patient With Fever and Rash
B UPPER RESPIRATORY TRACT INFECTIONS
58 The Common Cold
59 Pharyngitis
60 Acute Laryngitis
61 Otitis Externa, Otitis Media, and Mastoiditis
62 Sinusitis
63 Epiglottitis
64 Infections of the Oral Cavity, Neck, and Head
C PLEUROPULMONARY AND BRONCHIAL INFECTIONS
65 Acute Bronchitis
66 Acute Exacerbations of Chronic Obstructive Pulmonary Disease
67 Acute Pneumonia
68 Pleural Effusion and Empyema
69 Bacterial Lung Abscess
70 Chronic Pneumonia
71 Cystic Fibrosis
D URINARY TRACT INFECTIONS
72 Urinary Tract Infections
E SEPSIS
73 Sepsis and Septic Shock
F INTRAABDOMINAL INFECTIONS
74 Peritonitis and Intraperitoneal Abscesses
75 Infections of the Liver and Biliary System (Liver Abscess, Cholangitis, Cholecystitis)
76 Pancreatic Infection
77 Splenic Abscess
78 Appendicitis
79 Diverticulitis and Neutropenic Enterocolitis
G CARDIOVASCULAR INFECTIONS
80 Endocarditis and Intravascular Infections
81 Prosthetic Valve Endocarditis
82 Infections of Nonvalvular Cardiovascular Devices
83 Prevention of Infective Endocarditis
84 Myocarditis and Pericarditis
85 Mediastinitis
H CENTRAL NERVOUS SYSTEM INFECTIONS
86 Approach to the Patient With Central Nervous System Infection
87 Acute Meningitis
88 Chronic Meningitis
89 Encephalitis
90 Brain Abscess
91 Subdural Empyema, Epidural Abscess, and Suppurative Intracranial Thrombophlebitis
92 Cerebrospinal Fluid Shunt and Drain Infections
I SKIN AND SOFT TISSUE INFECTIONS
93 Cellulitis, Necrotizing Fasciitis, and Subcutaneous Tissue Infections
94 Myositis and Myonecrosis
95 Lymphadenitis and Lymphangitis
J GASTROINTESTINAL INFECTIONS AND FOOD POISONING
96 Syndromes of Enteric Infection
97 Esophagitis
98 Diarrhea With Little or No Fever
99 Acute Dysentery Syndromes (Diarrhea With Fever)
100 Typhoid Fever, Paratyphoid Fever, and Typhoidal Fevers
101 Foodborne Disease
102 Tropical Sprue and Environmental Enteric Dysfunction
K BONE AND JOINT INFECTIONS
103 Infectious Arthritis of Native Joints
104 Osteomyelitis
105 Orthopedic Implant-Associated Infections
L DISEASES OF THE REPRODUCTIVE ORGANS AND SEXUALLY TRANSMITTED DISEASES
106 Genital Skin and Mucous Membrane Lesions
107 Urethritis
108 Vulvovaginitis and Cervicitis
109 Infections of the Female Pelvis
110 Prostatitis, Epididymitis, and Orchitis
M EYE INFECTIONS
111 Introduction to Eye Infections
112 Microbial Conjunctivitis
113 Microbial Keratitis
114 Endophthalmitis
115 Infectious Causes of Uveitis
116 Periocular Infections
N HEPATITIS
117 Viral Hepatitis
O ACQUIRED IMMUNODEFICIENCY SYNDROME
118 Global Perspectives on Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome
119 Epidemiology and Prevention of AIDS and HIV Infection, Including Preexposure Prophylaxis and HIV Vaccine Development
120 Diagnosis of Human Immunodeficiency Virus Infection
121 The Immunology of Human Immunodeficiency Virus Infection
122 General Clinical Manifestations of Human Immunodeficiency Virus Infection (Including Acute Retroviral Syndrome and Oral, Cutaneous, Renal, Ocular, Metabolic, and Cardiac Diseases)
123 Pulmonary Manifestations of Human Immunodeficiency Virus Infection
124 Gastrointestinal, Hepatobiliary, and Pancreatic Manifestations of Human Immunodeficiency Virus Infection
125 Neurologic Diseases Caused by Human Immunodeficiency Virus Type 1 and Opportunistic Infections
126 Human Immunodeficiency Virus Infection in Women
127 Pediatric Human Immunodeficiency Virus Infection
128 Antiretroviral Therapy for Human Immunodeficiency Virus Infection
129 Management of Opportunistic Infections Associated With Human Immunodeficiency Virus Infection
P MISCELLANEOUS SYNDROMES
130 Chronic Fatigue Syndrome (Systemic Exertion Intolerance Disease)
III Infectious Diseases and Their Etiologic Agents
A VIRAL DISEASES
131 Biology of Viruses and Viral Diseases
132 Orthopoxviruses Vaccinia (Smallpox Vaccine), Variola (Smallpox), Monkeypox, and Cowpox
133 Other Poxviruses That Infect Humans: Parapoxviruses (Including Orf Virus), Molluscum Contagiosum, and Yatapoxviruses
134 Introduction to Herpesviridae
135 Herpes Simplex Virus
136 Chickenpox and Herpes Zoster (Varicella-Zoster Virus)
137 Cytomegalovirus
138 Epstein-Barr Virus (Infectious Mononucleosis, Epstein-Barr Virus-Associated Malignant Diseases, and Other Diseases)
139 Human Herpesvirus Types 6 and 7 (Exanthem Subitum)
140 Kaposi Sarcoma-Associated Herpesvirus (Human Herpesvirus 8)
141 Herpes B Virus
142 Adenoviruses
143 Papillomaviruses
144 JC, BK, and Other Polyomaviruses: Progressive Multifocal Leukoencephalopathy (PML)
145 Hepatitis B Virus
146 Hepatitis Delta Virus
147 Human Parvoviruses, Including Parvovirus B19V and Human Bocaparvoviruses
148 Orthoreoviruses and Orbiviruses
149 Coltiviruses (Colorado Tick Fever Virus) and Seadornaviruses
150 Rotaviruses
151 Alphaviruses (Chikungunya, Eastern Equine Encephalitis)
152 Rubella Virus (German Measles)
153 Flaviviruses (Dengue, Yellow Fever, Japanese Encephalitis, West Nile Encephalitis, Usutu Encephalitis, St. Louis Encephalitis, Tick-Borne Encephalitis, Kyasanur Forest Disease, Alkhurma Hemorrhagic Fever, Zika)
154 Hepatitis C
155 Coronaviruses, Including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS)
156 Parainfluenza Viruses
157 Mumps Virus
158 Respiratory Syncytial Virus
159 Human Metapneumovirus
160 Measles Virus (Rubeola)
161 Zoonotic Paramyxoviruses: Nipah, Hendra, and Menangle Viruses
162 Vesicular Stomatitis Virus and Related Vesiculoviruses (Chandipura Virus)
163 Rabies (Rhabdoviruses)
164 Marburg and Ebola Virus Hemorrhagic Fevers
165 Influenza Viruses, Including Avian Influenza and Swine Influenza
166 California Encephalitis, Hantavirus Pulmonary Syndrome, Hantavirus Hemorrhagic Fever With Renal Syndrome, and Bunyavirus Hemorrhagic Fevers
167 Lymphocytic Choriomeningitis Virus, Lassa Virus, and the South American Hemorrhagic Fevers (Arenaviruses)
168 Human T-Cell Leukemia Viruses (HTLV-1, HTLV-2)
169 Human Immunodeficiency Viruses
170 Introduction to the Human Enteroviruses and Parechoviruses
171 Poliovirus
172 Coxsackieviruses, Echoviruses, and Numbered Enteroviruses (EV-A71, EVD-68, EVD-70)
173 Parechoviruses
174 Hepatitis A Virus
175 Rhinovirus
176 Noroviruses and Sapoviruses (Caliciviruses)
177 Astroviruses and Picobirnaviruses
178 Hepatitis E Virus
B PRION DISEASES
179 Prions and Prion Disease of the Central Nervous System (Transmissible Neurodegenerative Diseases)
C CHLAMYDIAL DISEASES
180 Chlamydia trachomatis (Trachoma and Urogenital Infections)
181 Psittacosis (Due to Chlamydia...