Zum Hauptinhalt springen
Dekorationsartikel gehören nicht zum Leistungsumfang.
Lipids
Biochemistry, Biotechnology and Health
Taschenbuch von Denis J. Murphy (u. a.)
Sprache: Englisch

79,00 €*

inkl. MwSt.

Versandkostenfrei per Post / DHL

Aktuell nicht verfügbar

Kategorien:
Beschreibung

For the Sixth Edition of this highly regarded textbook devoted to lipids, the title has been modified from Lipid Biochemistry to Lipids to acknowledge the coming together of biological and medical sciences, the increasingly blurred boundaries between them and the growing importance of lipids in diverse aspects of science and technology. The principal aims of this new edition - to inform students and researchers about lipids, to assist teachers and encourage further research - have not changed since previous editions.

Significant advances in lipid science have demanded yet another extensive rewriting for this edition, with the addition of two new authors, to cover new knowledge of genes coding for proteins involved in lipid metabolism, the many lipids involved in cell signalling, the roles of lipids in health and disease and new developments in biotechnology in support of agriculture and industry.

An introductory chapter summarizes the types of lipids covered and their identification and provides a guide to the contents. Chapters contain boxes illustrating special topics, key point summaries and suggested further reading.

Lipids: 6th Edition provides a huge wealth of information for upper-level students of biological and clinical sciences, food science and nutrition, and for professionals working in academic and industrial research. Libraries in all universities and research establishments where biological, medical and food and nutritional sciences are studied and taught should have copies of this excellent and comprehensive new edition on their shelves.

About the authors
Michael Gurr was Visiting Professor in Human Nutrition at Reading and Oxford Brookes Universities, UK
John Harwood is a Professor of Biochemistry, School of Biosciences, Cardiff University, UK
Keith Frayn is Emeritus Professor of Human Metabolism, University of Oxford, UK
Denis Murphy is Professor of Biotechnology, School of Applied Sciences, University of South Wales, UK
Robert Michell is Professor of Biochemistry, School of Biosciences, University of Birmingham, UK

For the Sixth Edition of this highly regarded textbook devoted to lipids, the title has been modified from Lipid Biochemistry to Lipids to acknowledge the coming together of biological and medical sciences, the increasingly blurred boundaries between them and the growing importance of lipids in diverse aspects of science and technology. The principal aims of this new edition - to inform students and researchers about lipids, to assist teachers and encourage further research - have not changed since previous editions.

Significant advances in lipid science have demanded yet another extensive rewriting for this edition, with the addition of two new authors, to cover new knowledge of genes coding for proteins involved in lipid metabolism, the many lipids involved in cell signalling, the roles of lipids in health and disease and new developments in biotechnology in support of agriculture and industry.

An introductory chapter summarizes the types of lipids covered and their identification and provides a guide to the contents. Chapters contain boxes illustrating special topics, key point summaries and suggested further reading.

Lipids: 6th Edition provides a huge wealth of information for upper-level students of biological and clinical sciences, food science and nutrition, and for professionals working in academic and industrial research. Libraries in all universities and research establishments where biological, medical and food and nutritional sciences are studied and taught should have copies of this excellent and comprehensive new edition on their shelves.

About the authors
Michael Gurr was Visiting Professor in Human Nutrition at Reading and Oxford Brookes Universities, UK
John Harwood is a Professor of Biochemistry, School of Biosciences, Cardiff University, UK
Keith Frayn is Emeritus Professor of Human Metabolism, University of Oxford, UK
Denis Murphy is Professor of Biotechnology, School of Applied Sciences, University of South Wales, UK
Robert Michell is Professor of Biochemistry, School of Biosciences, University of Birmingham, UK

Inhaltsverzeichnis

Preface xv

Acknowledgements xvii

About the authors xix

About the companion website xxi

1 Lipids: definitions naming methods and a guide to the contents of this book 1

1.1 Introduction 1

1.2 Definitions 1

1.3 Structural chemistry and nomenclature 1

1.4 Lipidomics 4

1.5 A guide to the contents of this book 8

Key points 11

Further reading 12

2 Important biological lipids and their structures 13

2.1 Structure and properties of fatty acids 13

2.2 Storage lipids - triacylglycerols and wax esters 20

2.3 Membrane lipids 26

Key points 42

Further reading 42

3 Fatty acid metabolism 44

3.1 The biosynthesis of fatty acids 44

3.2 Degradation of fatty acids 85

3.3 Chemical peroxidation is an important reaction particularly of polyunsaturated fatty acids 95

3.4 Peroxidation catalysed by lipoxygenase enzymes 96

3.5 Essential fatty acids and the biosynthesis of eicosanoids 100

Key points 120

Further reading 121

4 The metabolism of complex lipids 124

4.1 The biosynthesis of triacylglycerols 124

4.2 The catabolism of acylglycerols 133

4.3 The integration and control of animal acylglycerol metabolism 136

4.4 Wax esters 143

4.5 Phosphoglyceride biosynthesis 146

4.6 Degradation of phospholipids 157

4.7 Metabolism of glycosylglycerides 163

4.8 Metabolism of sphingolipids 165

4.9 Cholesterol biosynthesis 173

Key points 182

Further reading 183

5 Roles of lipids in cellular structures 187

5.1 Lipid assemblies 187

5.2 Role of lipids in cellular evolution 193

5.3 Membrane structure 201

5.4 Membrane function 206

5.5 Intracellular lipid droplets 215

5.6 Extracellular lipid assemblies 222

Key points 226

Further reading 227

6 Dietary lipids and their biological roles 229

6.1 Lipids in food 229

6.2 Roles of dietary lipids 233

Key points 251

Further reading 251

7 Lipid assimilation and transport 253

7.1 Lipid digestion and absorption 253

7.2 Transport of lipids in the blood: plasma lipoproteins 261

7.3 The coordination of lipid metabolism in the body 275

Key points 284

Further reading 285

8 Lipids in transmembrane signalling and cell regulation 287

8.1 Phosphoinositides have diverse roles in cell signalling and cell compartmentation 288

8.2 Endocannabinoid signalling 299

8.3 Lysophosphatidate and sphingosine 1-phosphate in the circulation regulate cell motility and proliferation 299

8.4 Signalling by phospholipase D at least partly through phosphatidate 300

8.5 Ceramide regulates apoptosis and other cell responses 301

Key points 302

Further reading 303

9 The storage of triacylglycerols in animals and plants 304

9.1 White adipose tissue depots and triacylglycerol storage in animals 304

9.2 Brown adipose tissue and its role in thermogenesis 310

9.3 Lipid storage in plants 313

Key points 314

Further reading 315

10 Lipids in health and disease 317

10.1 Inborn errors of lipid metabolism 317

10.2 Lipids and cancer 323

10.3 Lipids and immune function 328

10.4 Effects of too much or too little adipose tissue: obesity and lipodystrophies 338

10.5 Disorders of lipoprotein metabolism 349

Key points 364

Further reading 365

11 Lipid technology and biotechnology 367

11.1 Introduction 367

11.2 Lipid technologies: from surfactants to biofuels 367

11.3 Lipids in foods 375

11.4 Modifiying lipids in foods 379

11.5 Modifying lipids in nonedible products 383

11.6 Lipids and genetically modified organisms 385

Key points 390

Further reading 390

Index and list of abbreviations 391

Details
Erscheinungsjahr: 2016
Fachbereich: Biophysik
Genre: Biologie, Importe
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Inhalt: Kartoniert / Broschiert
ISBN-13: 9781118501139
ISBN-10: 1118501136
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Murphy, Denis J.
Harwood, John L.
Frayn, Keith N.
Gurr, Michael I.
Michell, Robert H.
Auflage: 6. Auflage
Hersteller: John Wiley and Sons Ltd
Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de
Maße: 246 x 189 x 24 mm
Von/Mit: Denis J. Murphy (u. a.)
Erscheinungsdatum: 26.08.2016
Gewicht: 0,86 kg
Artikel-ID: 129723054
Inhaltsverzeichnis

Preface xv

Acknowledgements xvii

About the authors xix

About the companion website xxi

1 Lipids: definitions naming methods and a guide to the contents of this book 1

1.1 Introduction 1

1.2 Definitions 1

1.3 Structural chemistry and nomenclature 1

1.4 Lipidomics 4

1.5 A guide to the contents of this book 8

Key points 11

Further reading 12

2 Important biological lipids and their structures 13

2.1 Structure and properties of fatty acids 13

2.2 Storage lipids - triacylglycerols and wax esters 20

2.3 Membrane lipids 26

Key points 42

Further reading 42

3 Fatty acid metabolism 44

3.1 The biosynthesis of fatty acids 44

3.2 Degradation of fatty acids 85

3.3 Chemical peroxidation is an important reaction particularly of polyunsaturated fatty acids 95

3.4 Peroxidation catalysed by lipoxygenase enzymes 96

3.5 Essential fatty acids and the biosynthesis of eicosanoids 100

Key points 120

Further reading 121

4 The metabolism of complex lipids 124

4.1 The biosynthesis of triacylglycerols 124

4.2 The catabolism of acylglycerols 133

4.3 The integration and control of animal acylglycerol metabolism 136

4.4 Wax esters 143

4.5 Phosphoglyceride biosynthesis 146

4.6 Degradation of phospholipids 157

4.7 Metabolism of glycosylglycerides 163

4.8 Metabolism of sphingolipids 165

4.9 Cholesterol biosynthesis 173

Key points 182

Further reading 183

5 Roles of lipids in cellular structures 187

5.1 Lipid assemblies 187

5.2 Role of lipids in cellular evolution 193

5.3 Membrane structure 201

5.4 Membrane function 206

5.5 Intracellular lipid droplets 215

5.6 Extracellular lipid assemblies 222

Key points 226

Further reading 227

6 Dietary lipids and their biological roles 229

6.1 Lipids in food 229

6.2 Roles of dietary lipids 233

Key points 251

Further reading 251

7 Lipid assimilation and transport 253

7.1 Lipid digestion and absorption 253

7.2 Transport of lipids in the blood: plasma lipoproteins 261

7.3 The coordination of lipid metabolism in the body 275

Key points 284

Further reading 285

8 Lipids in transmembrane signalling and cell regulation 287

8.1 Phosphoinositides have diverse roles in cell signalling and cell compartmentation 288

8.2 Endocannabinoid signalling 299

8.3 Lysophosphatidate and sphingosine 1-phosphate in the circulation regulate cell motility and proliferation 299

8.4 Signalling by phospholipase D at least partly through phosphatidate 300

8.5 Ceramide regulates apoptosis and other cell responses 301

Key points 302

Further reading 303

9 The storage of triacylglycerols in animals and plants 304

9.1 White adipose tissue depots and triacylglycerol storage in animals 304

9.2 Brown adipose tissue and its role in thermogenesis 310

9.3 Lipid storage in plants 313

Key points 314

Further reading 315

10 Lipids in health and disease 317

10.1 Inborn errors of lipid metabolism 317

10.2 Lipids and cancer 323

10.3 Lipids and immune function 328

10.4 Effects of too much or too little adipose tissue: obesity and lipodystrophies 338

10.5 Disorders of lipoprotein metabolism 349

Key points 364

Further reading 365

11 Lipid technology and biotechnology 367

11.1 Introduction 367

11.2 Lipid technologies: from surfactants to biofuels 367

11.3 Lipids in foods 375

11.4 Modifiying lipids in foods 379

11.5 Modifying lipids in nonedible products 383

11.6 Lipids and genetically modified organisms 385

Key points 390

Further reading 390

Index and list of abbreviations 391

Details
Erscheinungsjahr: 2016
Fachbereich: Biophysik
Genre: Biologie, Importe
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Inhalt: Kartoniert / Broschiert
ISBN-13: 9781118501139
ISBN-10: 1118501136
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Murphy, Denis J.
Harwood, John L.
Frayn, Keith N.
Gurr, Michael I.
Michell, Robert H.
Auflage: 6. Auflage
Hersteller: John Wiley and Sons Ltd
Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de
Maße: 246 x 189 x 24 mm
Von/Mit: Denis J. Murphy (u. a.)
Erscheinungsdatum: 26.08.2016
Gewicht: 0,86 kg
Artikel-ID: 129723054
Sicherheitshinweis