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Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology
Buch von Wanda M Haschek (u. a.)
Sprache: Englisch

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Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters.

Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.¿

Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters.

Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.¿

Inhaltsverzeichnis
1. Toxicology Pathology: An Introduction Part 1 Principles of Toxicologic Pathology2. Biochemical and Molecular Basis of Toxicity
3. ADME Principles in Small Molecule Drug Discovery and Development: An Industrial Perspective
4. Biotherapeutic ADME and PK/PD Principles
5. Principles of Pharmacodynamics and Toxicodynamics
6. Morphologic Manifestations of Toxic Cell Injury
7. The Role of Pathology in Evaluation of Reproductive, Developmental, and Juvenile Toxicity
8. Carcinogenesis: Mechanisms and Evaluation Part 2 Methods in Toxicologic Pathology9. Basic Approaches to Anatomic Toxicologic Pathology
10. Clinical Pathology in Nonclinical Toxicity Testing
11. Special Techniques in Toxicologic Pathology
12. Digital Pathology and Tissue Image Analysis
13. In Vivo Small Animal Imaging: A Comparison to Gross and Histopathologic Observations in Animal Models
14. Biomarkers: Discovery, Qualification and Application
15. Toxicogenomics: A Primer for Toxicologic Pathologists
16. Experimental Design and Statistical Analysis for Toxicologic Pathologists Part 3 Animal and Alternative Models in Toxicologic Research17. Animal Models in Toxicologic Research: Rodents
18. Animal Models in Toxicologic Research: Rabbit
19. Animal Models in Toxicologic Research: Dog
20. Animal Models in Toxicologic Research: Pig
21. Animal Models in Toxicologic Research: Nonhuman Primate
22. Animal Models in Toxicologic Research: Non-mammalian
23. Genetically Engineered Animal Models in Toxicologic Research
24. Alternative Models in Biomedical Research: In Silico, In Vitro, Ex Vivo, and Non-Traditional In Vivo Approaches Part 4 Practice of Toxicologic Pathology25. Nomenclature and Diagnostic Resources in Anatomic Toxicologic Pathology
26. Pathology Peer Review
27. Pathology and GLPs, Quality Control and Quality Assurance
28. Practices to Optimize Generation, Interpretation, And Reporting of Pathology Data from Toxicity Studies
29. Issues in Laboratory Animal Science that Impact Toxicologic Pathology
Details
Erscheinungsjahr: 2022
Fachbereich: Toxikologie
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Buch
Inhalt: Gebunden
ISBN-13: 9780128210444
ISBN-10: 0128210443
Sprache: Englisch
Einband: Gebunden
Redaktion: Haschek, Wanda M
Rousseaux, Colin G
Wallig, Matthew A
Bolon, Brad
Auflage: 4th edition
Hersteller: Elsevier Science
Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de
Maße: 280 x 217 x 60 mm
Von/Mit: Wanda M Haschek (u. a.)
Erscheinungsdatum: 05.01.2022
Gewicht: 3,21 kg
Artikel-ID: 133177321
Inhaltsverzeichnis
1. Toxicology Pathology: An Introduction Part 1 Principles of Toxicologic Pathology2. Biochemical and Molecular Basis of Toxicity
3. ADME Principles in Small Molecule Drug Discovery and Development: An Industrial Perspective
4. Biotherapeutic ADME and PK/PD Principles
5. Principles of Pharmacodynamics and Toxicodynamics
6. Morphologic Manifestations of Toxic Cell Injury
7. The Role of Pathology in Evaluation of Reproductive, Developmental, and Juvenile Toxicity
8. Carcinogenesis: Mechanisms and Evaluation Part 2 Methods in Toxicologic Pathology9. Basic Approaches to Anatomic Toxicologic Pathology
10. Clinical Pathology in Nonclinical Toxicity Testing
11. Special Techniques in Toxicologic Pathology
12. Digital Pathology and Tissue Image Analysis
13. In Vivo Small Animal Imaging: A Comparison to Gross and Histopathologic Observations in Animal Models
14. Biomarkers: Discovery, Qualification and Application
15. Toxicogenomics: A Primer for Toxicologic Pathologists
16. Experimental Design and Statistical Analysis for Toxicologic Pathologists Part 3 Animal and Alternative Models in Toxicologic Research17. Animal Models in Toxicologic Research: Rodents
18. Animal Models in Toxicologic Research: Rabbit
19. Animal Models in Toxicologic Research: Dog
20. Animal Models in Toxicologic Research: Pig
21. Animal Models in Toxicologic Research: Nonhuman Primate
22. Animal Models in Toxicologic Research: Non-mammalian
23. Genetically Engineered Animal Models in Toxicologic Research
24. Alternative Models in Biomedical Research: In Silico, In Vitro, Ex Vivo, and Non-Traditional In Vivo Approaches Part 4 Practice of Toxicologic Pathology25. Nomenclature and Diagnostic Resources in Anatomic Toxicologic Pathology
26. Pathology Peer Review
27. Pathology and GLPs, Quality Control and Quality Assurance
28. Practices to Optimize Generation, Interpretation, And Reporting of Pathology Data from Toxicity Studies
29. Issues in Laboratory Animal Science that Impact Toxicologic Pathology
Details
Erscheinungsjahr: 2022
Fachbereich: Toxikologie
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Buch
Inhalt: Gebunden
ISBN-13: 9780128210444
ISBN-10: 0128210443
Sprache: Englisch
Einband: Gebunden
Redaktion: Haschek, Wanda M
Rousseaux, Colin G
Wallig, Matthew A
Bolon, Brad
Auflage: 4th edition
Hersteller: Elsevier Science
Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de
Maße: 280 x 217 x 60 mm
Von/Mit: Wanda M Haschek (u. a.)
Erscheinungsdatum: 05.01.2022
Gewicht: 3,21 kg
Artikel-ID: 133177321
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