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Handbook of the Biology of Aging
Taschenbuch von Nicolas Musi (u. a.)
Sprache: Englisch

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Beschreibung
"Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and metabolomics methodologies applied to aging related problems. Sections cover longevity pathways and interventions that modulate aging, innovative tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, and much more"--
"Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and metabolomics methodologies applied to aging related problems. Sections cover longevity pathways and interventions that modulate aging, innovative tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, and much more"--
Inhaltsverzeichnis

Part I: Basic mechanisms, underlying physiological changes, model organisms and interventions

1. Longevity as a complex genetic trait

2. DNA damage and repair in aging

3. Mechanisms of cell senescence in aging

4. The nature of aging and the geroscience hypothesis

5. Sirtuins, healthspan, and longevity in mammals

6. Integrative genomics of aging

7. Thermogenesis and aging

8. Yeast as a model organism for aging research

9. Model organisms (invertebrates)

10. NIA Interventions Testing Program: A collaborative approach for investigating interventions to promote healthy aging

11. Aging in nonhuman primates

Part II: Organ systems in humans and other animals, human health and longevity

12. Senotherapeutics: Experimental therapy of cellular senescence

13. The role of neurosensory systems in the modulation of aging

14. Aging of the sensory systems: hearing and vision disorders

15. Cardiac aging

16. The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention

17. Microbiome changes in aging

18. Lipidomics of aging

19. Trends in morbidity, healthy life expectancy, and the compression of morbidity

Details
Erscheinungsjahr: 2021
Fachbereich: Angewandte Psychologie
Genre: Psychologie
Rubrik: Geisteswissenschaften
Medium: Taschenbuch
Seiten: 468
Inhalt: Kartoniert / Broschiert
ISBN-13: 9780128159620
ISBN-10: 0128159626
Sprache: Englisch
Einband: Kartoniert / Broschiert
Redaktion: Musi, Nicolas
Hornsby, Peter
Hersteller: Elsevier Science Publishing Co Inc
Maße: 276 x 218 x 27 mm
Von/Mit: Nicolas Musi (u. a.)
Erscheinungsdatum: 22.01.2021
Gewicht: 1,318 kg
preigu-id: 118713039
Inhaltsverzeichnis

Part I: Basic mechanisms, underlying physiological changes, model organisms and interventions

1. Longevity as a complex genetic trait

2. DNA damage and repair in aging

3. Mechanisms of cell senescence in aging

4. The nature of aging and the geroscience hypothesis

5. Sirtuins, healthspan, and longevity in mammals

6. Integrative genomics of aging

7. Thermogenesis and aging

8. Yeast as a model organism for aging research

9. Model organisms (invertebrates)

10. NIA Interventions Testing Program: A collaborative approach for investigating interventions to promote healthy aging

11. Aging in nonhuman primates

Part II: Organ systems in humans and other animals, human health and longevity

12. Senotherapeutics: Experimental therapy of cellular senescence

13. The role of neurosensory systems in the modulation of aging

14. Aging of the sensory systems: hearing and vision disorders

15. Cardiac aging

16. The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention

17. Microbiome changes in aging

18. Lipidomics of aging

19. Trends in morbidity, healthy life expectancy, and the compression of morbidity

Details
Erscheinungsjahr: 2021
Fachbereich: Angewandte Psychologie
Genre: Psychologie
Rubrik: Geisteswissenschaften
Medium: Taschenbuch
Seiten: 468
Inhalt: Kartoniert / Broschiert
ISBN-13: 9780128159620
ISBN-10: 0128159626
Sprache: Englisch
Einband: Kartoniert / Broschiert
Redaktion: Musi, Nicolas
Hornsby, Peter
Hersteller: Elsevier Science Publishing Co Inc
Maße: 276 x 218 x 27 mm
Von/Mit: Nicolas Musi (u. a.)
Erscheinungsdatum: 22.01.2021
Gewicht: 1,318 kg
preigu-id: 118713039
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