Handbook of Juvenile Idiopathic Arthritis

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Sprache: Englisch

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Beschreibung

This handbook is an in-depth and comprehensive guide for the treatment and management of patients with juvenile idiopathic arthritis. The handbook provides an informative review of the disease looking at the epidemiology, etiology and pathogenesis, issues of diagnosis and classification, consequences and complications, general treatment aspects, as well as both non pharmacologic and pharmacologic therapy whilst considering the future outlook for patients with juvenile idiopathic arthritis. Juvenile idiopathic arthritis is the most common type of arthritis found in children and adolescents, affecting about 1 in 1,000 children. It is a chronic disease which causes inflammation, pain and swelling of the affected joints and can affect joints in any part of the body. This Handbook provides an unbiased, informative discussion of the current and emerging treatments in this field.

Über den Autor

Angelo Ravelli is Associate Professor of Pediatrics at the School of Medicine of the University of Genoa, Italy, a position held since 2006. He is Chief of the Centre of Clinimetrics of the Istituto Giannina Gaslini of Genoa, Italy, a position he has held since 2012. Previously, he was Chief of the Interventional Rheumatology Unit at the same institution. After completion of a degree in medicine, Dr Ravelli specialized in paediatrics and allergology. His field of clinical and research activity focuses on paediatric rheumatology.

Dr Ravelli has been invited to speak in more than 200 national and international meetings and has published more than 220 full-length articles in international scientific journals, with a total impact factor of more than 1,200 and an h-index of 43. He has received numerous grants and awards, including the Gerolamo Prize for Excellence in Research in 2004. He is Associate Editor of Pediatric Rheumatology Online Journal, Assistant Editor of Clinical and Experimental Rheumatology and serves on the Editorial Board of The Journal of Rheumatology and Arthritis Care & Research. He is a member of the Executive Committee of the European Rheumatology Research Foundation and was Chairman of the Lupus Working Group of the Pediatric Rheumatology European Society (PReS) from 2004 to 2010.

Inhaltsverzeichnis

Introduction

Disease overview

Epidemiology

Etiology and pathogenesis

Environmental factors

Genetic susceptibility

Role of humoral and cell-mediated immunity

Pathogenesis of systemic arthritis

Pathophysiology of macrophage activation syndrome

Disease classification

Classification criteria

Challenges in classification

Clinical manifestations

Systemic arthritis

Rheumatoid factor-negative polyarthritis

Rheumatoid factor-positive polyarthritis

Oligoarthritis

Enthesitis-related arthritis

Psoriatic arthritis

Undifferentiated arthritis

Diagnosis

Clinical assessment

Imaging

Biomarkers

Differential diagnosis

Consequences and complications

Disease course of different subtypes

Skeletal and growth abnormalities

Ophthalmologic complications

Macrophage activation syndrome

General treatment aspects

Goals of treatment

Measuring treatment response

Treatment recommendations

A multidisciplinary approach to treatment

Special considerations in the pediatric patient

Management of patients with

juvenile idiopathic arthritis

Psychosocial factors

Physical therapy

Other non-pharmacologic interventions

Non-steroidal anti-inflammatory drugs

Intra-articular corticosteroids

Systemic corticosteroids

Conventional disease-modifying anti-rheumatic drugs

Biologic disease-modifying anti-rheumatic drugs

Safety of biologics

Other pharmacologic interventions

Management of iridocyclitis

Management of macrophage activation syndrome

Specific issues

Health-related quality of life

Vaccination

Treatment discontinuation after disease remission

Transition to adult care

Outcome, prognosis and future outlook

Long-term outcome and its prediction

Mortality

Future outlook

Details

Erscheinungsjahr:	2015
Fachbereich:	Allgemeine Lexika
Genre:	Medizin
Rubrik:	Wissenschaften
Medium:	Taschenbuch
Inhalt:	xv 124 S. 17 s/w Illustr. 6 farbige Illustr. 22 s/w Tab. 16 farbige Tab. 124 p. 23 illus. 6 illus. in color.
ISBN-13:	9783319081014
ISBN-10:	3319081012
Sprache:	Englisch
Herstellernummer:	86363869
Ausstattung / Beilage:	Paperback
Einband:	Kartoniert / Broschiert
Autor:	Ravelli, Angelo
Auflage:	1st ed. 2016
Hersteller:	Springer International Publishing Springer International Publishing AG
Maße:	203 x 127 x 8 mm
Von/Mit:	Angelo Ravelli
Erscheinungsdatum:	30.10.2015
Gewicht:	0,159 kg

Artikel-ID: 105052096