Guerrilla Warfare (Spanish: La Guerra de Guerrillas) is a military handbook written by Marxist revolutionary Che Guevara following the Cuban Revolution. It became a reference for thousands of guerrilla fighters in various countries around the world. The book draws upon Guevara's personal experience as a guerrilla soldier during the Cuban Revolution.

The book identifies reasons for, prerequisites, and lessons of guerrilla warfare. The principal reason to conduct guerrilla warfare within a country is because all peaceful and legal means of recourse have been exhausted. The most important prerequisite for conducting guerrilla warfare in a country is the popular support of its people for the guerrilla army. Che asserted that the success of the Cuban Revolution provided three lessons: Popular forces can win a war against a regular army, Guerrillas can create their own favorable conditions (not needing to wait for ideal conditions to take shape), and in Underdeveloped America, the basic place of operation for a guerrilla army is the countryside.