Genome-Wide Association Studies | Taschenbuch

Cover: 9789811381799 | Genome-Wide Association Studies | Tatsuhiko Tsunoda (u. a.) | Buch

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Sprache: Englisch

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Beschreibung

This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS on genomic research into a variety of common diseases, including cardiovascular, autoimmune, diabetic, cancer, and infectious diseases. The book will equip readers with a sound understanding both of the types of disease and phenotypes that are suited for GWAS and of the ways in which a road map resulting from GWAS can lead to the realization of personalized/precision medicine: functional analysis, drug seeds, pathway analysis, disease mechanism, risk prediction, and diagnosis.

Über den Autor

Tatsuhiko Tsunoda, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, 113-8510 Tokyo, Japan

Toshihiro Tanaka, BioResource Research Center, Tokyo Medical and Dental University, 1-5-45 Yushima, 113-8510 Tokyo, 13 Japan

Yusuke Nakamura, Dept. of Medicine, University of Chicago, 900 E. 57th Street, 6240G, 60637 Chicago, IL, USA

Zusammenfassung

Examines the utility of GWAS in a range of common diseases

Identifies limitations and means of overcoming them

Offers guidance on recruitment of samples and data analysis

Looks to the future of GWAS and what lies beyond

Inhaltsverzeichnis

Genotyping and Statistical Analysis.- Genetics of coronary artery disease.- Genetic and Functional Genetics of Autoimmune Diseases.- Genome-Wide Association Study for Type 2 diabetes.- The association of single nucleotide polymorphisms with cancer risk.- Genetics of Infectious Diseases.- Pharmacogenomics.- The Future of and Beyond GWAS.

Details

Erscheinungsjahr:	2020
Fachbereich:	Andere Fachgebiete
Genre:	Importe , Medizin
Rubrik:	Wissenschaften
Medium:	Taschenbuch
Inhalt:	ix 209 S. 2 s/w Illustr. 7 farbige Illustr. 209 p. 9 illus. 7 illus. in color.
ISBN-13:	9789811381799
ISBN-10:	9811381798
Sprache:	Englisch
Einband:	Kartoniert / Broschiert
Redaktion:	Tsunoda, Tatsuhiko Tanaka, Toshihiro Nakamura, Yusuke
Herausgeber:	Tatsuhiko Tsunoda/Toshihiro Tanaka/Yusuke Nakamura
Hersteller:	Springer Springer Singapore
Verantwortliche Person für die EU:	Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße:	235 x 155 x 12 mm
Von/Mit:	Tatsuhiko Tsunoda (u. a.)
Erscheinungsdatum:	14.11.2020
Gewicht:	0,388 kg