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Genome Data Analysis
Taschenbuch von Ju Han Kim
Sprache: Englisch

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Beschreibung
This textbook describes recent advances in genomics and bioinformatics and provides numerous examples of genome data analysis that illustrate its relevance to real world problems and will improve the reader¿s bioinformatics skills. Basic data preprocessing with normalization and filtering, primary pattern analysis, and machine learning algorithms using R and Python are demonstrated for gene-expression microarrays, genotyping microarrays, next-generation sequencing data, epigenomic data, and biological network and semantic analyses. In addition, detailed attention is devoted to integrative genomic data analysis, including multivariate data projection, gene-metabolic pathway mapping, automated biomolecular annotation, text mining of factual and literature databases, and integrated management of biomolecular databases.

The textbook is primarily intended for life scientists, medical scientists, statisticians, data processing researchers, engineers, and other beginners in bioinformatics who are experiencing difficulty in approaching the field. However, it will also serve as a simple guideline for experts unfamiliar with the new, developing subfield of genomic analysis within bioinformatics.
This textbook describes recent advances in genomics and bioinformatics and provides numerous examples of genome data analysis that illustrate its relevance to real world problems and will improve the reader¿s bioinformatics skills. Basic data preprocessing with normalization and filtering, primary pattern analysis, and machine learning algorithms using R and Python are demonstrated for gene-expression microarrays, genotyping microarrays, next-generation sequencing data, epigenomic data, and biological network and semantic analyses. In addition, detailed attention is devoted to integrative genomic data analysis, including multivariate data projection, gene-metabolic pathway mapping, automated biomolecular annotation, text mining of factual and literature databases, and integrated management of biomolecular databases.

The textbook is primarily intended for life scientists, medical scientists, statisticians, data processing researchers, engineers, and other beginners in bioinformatics who are experiencing difficulty in approaching the field. However, it will also serve as a simple guideline for experts unfamiliar with the new, developing subfield of genomic analysis within bioinformatics.
Über den Autor

Professor. Ju Han Kim, Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul , South Korea.

Inhaltsverzeichnis
Part 1. BIOINFORMATICS FOR LIFE AND PERSONAL GENOME INTERPRETATION.- Chapter 1. Bioinformatics For Life.- Chapter 2. Next Generation Sequencing and Personal Genome Data Analysis.- Chapter 3. Personal Genome Data Analysis.- Chapter 4. Personal Genome Interpretation and Disease Risk Prediction.- Part 2. ADVANCED MICROARRAY DATA ANALYSIS.- Chapter 5. Advanced Microarray Data Analysis.- Chapter 6. Gene Expression Data Analysis.- Chapter 7. Gene Ontology and Biological Pathway-based Analysis.- Chapter 8. Gene-set Approaches and Prognostic Subgroup Prediction.- Chapter 9. MicroRNA Data Analysis.- Part 3. NETWORK BIOLOGY, SEQUENCE, PATHWAY AND ONTOLOGY INFORMATICS.- Chapter 10. Network Biology, Sequence, Pathway and Ontology Informatics.- Chapter 11. Motif and Regulatory Sequence Analysis.- Chapter 12. Molecular Pathways and Gene Ontology.- Chapter 13. Biological Network Analysis.- Part 4. SNPS, GWAS AND CNVS, INFORMATICS FOR GENOME VARIANTS.- Chapter 14. SNPs, GWAS, CNVs: Informatics for Human Genome Variations.- Chapter 15. SNP Data Analysis.- Chapter 16. GWAS Data Analysis.- Chapter 17. CNV Data Analysis.- Part 5. METAGENOME AND EPIGENOME, BASIC DATA ANALYSIS.- Chapter 18. Metagenome and Epigenome Data Analysis.- Chapter 19. Metagenome Data Analysis.- Chapter 20. Epigenome Databases and Tools.- Chapter 21. Epigenome Data Analysis.- Appendix A. BASIC PRACTICE USING R FOR DATA ANALYSIS.- Appendix B. APPLICATION PROGRAM FOR GENOME DATA ANALYSIS INSTALL GUIDE.
Details
Erscheinungsjahr: 2019
Fachbereich: Allgemeines
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Seiten: 384
Reihe: Learning Materials in Biosciences
Inhalt: xvi
367 S.
409 s/w Illustr.
236 farbige Illustr.
367 p. 645 illus.
236 illus. in color.
ISBN-13: 9789811319419
ISBN-10: 9811319413
Sprache: Englisch
Herstellernummer: 978-981-13-1941-9
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Kim, Ju Han
Auflage: 1st ed. 2019
Hersteller: Springer Singapore
Springer Nature Singapore
Learning Materials in Biosciences
Maße: 240 x 168 x 20 mm
Von/Mit: Ju Han Kim
Erscheinungsdatum: 10.05.2019
Gewicht: 0,72 kg
preigu-id: 114052546
Über den Autor

Professor. Ju Han Kim, Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul , South Korea.

Inhaltsverzeichnis
Part 1. BIOINFORMATICS FOR LIFE AND PERSONAL GENOME INTERPRETATION.- Chapter 1. Bioinformatics For Life.- Chapter 2. Next Generation Sequencing and Personal Genome Data Analysis.- Chapter 3. Personal Genome Data Analysis.- Chapter 4. Personal Genome Interpretation and Disease Risk Prediction.- Part 2. ADVANCED MICROARRAY DATA ANALYSIS.- Chapter 5. Advanced Microarray Data Analysis.- Chapter 6. Gene Expression Data Analysis.- Chapter 7. Gene Ontology and Biological Pathway-based Analysis.- Chapter 8. Gene-set Approaches and Prognostic Subgroup Prediction.- Chapter 9. MicroRNA Data Analysis.- Part 3. NETWORK BIOLOGY, SEQUENCE, PATHWAY AND ONTOLOGY INFORMATICS.- Chapter 10. Network Biology, Sequence, Pathway and Ontology Informatics.- Chapter 11. Motif and Regulatory Sequence Analysis.- Chapter 12. Molecular Pathways and Gene Ontology.- Chapter 13. Biological Network Analysis.- Part 4. SNPS, GWAS AND CNVS, INFORMATICS FOR GENOME VARIANTS.- Chapter 14. SNPs, GWAS, CNVs: Informatics for Human Genome Variations.- Chapter 15. SNP Data Analysis.- Chapter 16. GWAS Data Analysis.- Chapter 17. CNV Data Analysis.- Part 5. METAGENOME AND EPIGENOME, BASIC DATA ANALYSIS.- Chapter 18. Metagenome and Epigenome Data Analysis.- Chapter 19. Metagenome Data Analysis.- Chapter 20. Epigenome Databases and Tools.- Chapter 21. Epigenome Data Analysis.- Appendix A. BASIC PRACTICE USING R FOR DATA ANALYSIS.- Appendix B. APPLICATION PROGRAM FOR GENOME DATA ANALYSIS INSTALL GUIDE.
Details
Erscheinungsjahr: 2019
Fachbereich: Allgemeines
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Seiten: 384
Reihe: Learning Materials in Biosciences
Inhalt: xvi
367 S.
409 s/w Illustr.
236 farbige Illustr.
367 p. 645 illus.
236 illus. in color.
ISBN-13: 9789811319419
ISBN-10: 9811319413
Sprache: Englisch
Herstellernummer: 978-981-13-1941-9
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Kim, Ju Han
Auflage: 1st ed. 2019
Hersteller: Springer Singapore
Springer Nature Singapore
Learning Materials in Biosciences
Maße: 240 x 168 x 20 mm
Von/Mit: Ju Han Kim
Erscheinungsdatum: 10.05.2019
Gewicht: 0,72 kg
preigu-id: 114052546
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