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Cover: 9780198529965 | Gene Genealogies, Variation and Evolution | Jotun Hein (u. a.) | Buch
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Gene Genealogies, Variation and Evolution
A Primer in Coalescent Theory
Taschenbuch von Jotun Hein (u. a.)
Sprache: Englisch

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Beschreibung
Coalescent theory tells us what gene genealogies are expected to look like if populations have different demographic histories - i.e, population size, structure, etc. The aim of this book is to provide an accessible introduction to Coalescent Theory with a view towards data analysis. Coalescent Theory has in the last two decades moved from being an obscure technique that appealed to mathematical population geneticists to a central tool in data analysis of DNA sequences. The completion of the sequencing of the human genome and accompanying determination of SNPs and haplotypes will increase its importance even further. This textbook, rich in examples and illustrations, is suitable for a graduate course in statistics, population-, molecular-, and medical genetics.
Coalescent theory tells us what gene genealogies are expected to look like if populations have different demographic histories - i.e, population size, structure, etc. The aim of this book is to provide an accessible introduction to Coalescent Theory with a view towards data analysis. Coalescent Theory has in the last two decades moved from being an obscure technique that appealed to mathematical population geneticists to a central tool in data analysis of DNA sequences. The completion of the sequencing of the human genome and accompanying determination of SNPs and haplotypes will increase its importance even further. This textbook, rich in examples and illustrations, is suitable for a graduate course in statistics, population-, molecular-, and medical genetics.
Inhaltsverzeichnis
  • Preface

  • The basic coalescent

  • From genealogies to sequences

  • Trees and topologies

  • Extensions to the basic coalescent

  • The coalescent with recombination

  • Getting parameters from data

  • LD Mapping and the coalescent

  • Human evolution

  • Appendix: Web based tools

Details
Erscheinungsjahr: 2005
Fachbereich: Wahrscheinlichkeitstheorie
Genre: Mathematik
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
ISBN-13: 9780198529965
ISBN-10: 0198529961
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Hein, Jotun
Schierup, Mikkel
Wiuf, Carsten
Hersteller: OUP Oxford
Maße: 244 x 170 x 16 mm
Von/Mit: Jotun Hein (u. a.)
Erscheinungsdatum: 01.02.2005
Gewicht: 0,508 kg
Artikel-ID: 108631935
Inhaltsverzeichnis
  • Preface

  • The basic coalescent

  • From genealogies to sequences

  • Trees and topologies

  • Extensions to the basic coalescent

  • The coalescent with recombination

  • Getting parameters from data

  • LD Mapping and the coalescent

  • Human evolution

  • Appendix: Web based tools

Details
Erscheinungsjahr: 2005
Fachbereich: Wahrscheinlichkeitstheorie
Genre: Mathematik
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
ISBN-13: 9780198529965
ISBN-10: 0198529961
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Hein, Jotun
Schierup, Mikkel
Wiuf, Carsten
Hersteller: OUP Oxford
Maße: 244 x 170 x 16 mm
Von/Mit: Jotun Hein (u. a.)
Erscheinungsdatum: 01.02.2005
Gewicht: 0,508 kg
Artikel-ID: 108631935
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